Regulation of Ras p21 and RalA GTPases activity by quinine in mammary epithelial cells.

Autor: Bhatia V; Manitoba Chemosensory Biology Research Group and Department of Oral Biology, Dr. Gerald Niznick College of Dentistry, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada.; Children's Hospital Research Institute of Manitoba (CHRIM), Winnipeg, MB, R3E 3P4, Canada., Esmati L; Manitoba Chemosensory Biology Research Group and Department of Oral Biology, Dr. Gerald Niznick College of Dentistry, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada., Bhullar RP; Manitoba Chemosensory Biology Research Group and Department of Oral Biology, Dr. Gerald Niznick College of Dentistry, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada. Rajinder.Bhullar@umanitoba.ca.; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada. Rajinder.Bhullar@umanitoba.ca.

Publikováno v: Molecular and cellular biochemistry [Mol Cell Biochem] 2024 Mar; Vol. 479 (3), pp. 567-577. Date of Electronic Publication: 2023 May 02.

Low expression of RGL4 is associated with a poor prognosis and immune infiltration in lung adenocarcinoma patients.

Autor: Sun Y; Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China; Department of Oncology, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China., Zhang Y; Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China., Ren S; Department of Clinical Biobank, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226000, PR China; Department of Medicine, Nantong University Xinling College, Nantong, Jiangsu 226001, PR China., Li X; Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China., Yang P; Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China., Zhu J; Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China., Lin L; Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China., Wang Z; Department of Clinical Biobank, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226000, PR China. Electronic address: 1517073031@xlxy.ntu.edu.cn., Jia Y; Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China. Electronic address: jiayingjie1616@sina.com.

Publikováno v: International immunopharmacology [Int Immunopharmacol] 2020 Jun; Vol. 83, pp. 106454. Date of Electronic Publication: 2020 Apr 04.

RILP suppresses invasion of breast cancer cells by modulating the activity of RalA through interaction with RalGDS.

Autor: Wang Z; School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian, China., Zhou Y; School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian, China., Hu X; School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian, China., Chen W; School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian, China., Lin X; School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian, China., Sun L; School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian, China., Xu X; School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian, China., Hong W; School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian, China.; Institute of Molecular and Cell Biology, A*STAR (Agency for Science, Technology and Research), Singapore., Wang T; School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian, China.

Publikováno v: Cell death & disease [Cell Death Dis] 2015 Oct 15; Vol. 6, pp. e1923. Date of Electronic Publication: 2015 Oct 15.

Conserved electrostatic fields at the Ras-effector interface measured through vibrational Stark effect spectroscopy explain the difference in tilt angle in the Ras binding domains of Raf and RalGDS.

Autor: Walker DM; Department of Chemistry, Center for Nano- and Molecular Science and Technology, and Institute for Cell and Molecular Biology, The University of Texas at Austin, 1 University Station, A5300, Austin, TX 78712, USA. lwebb@cm.utexas.edu., Wang R, Webb LJ

Publikováno v: Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2014 Oct 07; Vol. 16 (37), pp. 20047-60.

Vibrational Stark effect spectroscopy at the interface of Ras and Rap1A bound to the Ras binding domain of RalGDS reveals an electrostatic mechanism for protein-protein interaction.

Autor: Stafford AJ; Department of Chemistry and Biochemistry and Institute for Cell and Molecular Biology, The University of Texas at Austin, 1 University Station, A5300, Austin, Texas 78712, USA., Ensign DL, Webb LJ

Publikováno v: The journal of physical chemistry. B [J Phys Chem B] 2010 Nov 25; Vol. 114 (46), pp. 15331-44. Date of Electronic Publication: 2010 Oct 22.