Inhibition of HBV Transcription From cccDNA With Nitazoxanide by Targeting the HBx–DDB1 Interaction

Autor: Rei Ishibashi, Motoyuki Otsuka, Eri Tanaka, Motoko Ohno, Mari Yamagami, Takahiro Kishikawa, Takahiro Seimiya, Kazuhiko Koike, Tatsunori Suzuki, Kazuma Sekiba

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 297-312 (2019)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Hepatitis B virus (HBV) infection is a major health concern worldwide. Although currently used nucleos(t)ide analogs efficiently inhibit viral replication, viral proteins transcribed from the episomal viral covalently closed circula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c7677e529575b879027fb0f0ac4368
https://doi.org/10.1016/j.jcmgh.2018.10.010