Zobrazeno 1 - 10
of 60
pro vyhledávání: '"NRTN"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Pia Runeberg-Roos, Elisa Piccinini, Anna-Maija Penttinen, Kert Mätlik, Hanna Heikkinen, Satu Kuure, Maxim M. Bespalov, Johan Peränen, Enrique Garea-Rodríguez, Eberhard Fuchs, Mikko Airavaara, Nisse Kalkkinen, Richard Penn, Mart Saarma
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 335-345 (2016)
In Parkinson's disease midbrain dopaminergic neurons degenerate and die. Oral medications and deep brain stimulation can relieve the initial symptoms, but the disease continues to progress. Growth factors that might support the survival, enhance the
Externí odkaz:
https://doaj.org/article/a3f501f9389e4ae69124b3f661ad8d55
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Christopher D. Herzog, Lamar Brown, Brian R. Kruegel, Alistair Wilson, Malú G. Tansey, Fred H. Gage, Eugene M. Johnson, Jr., Raymond T. Bartus
Publikováno v:
Neurobiology of Disease, Vol 58, Iss , Pp 38-48 (2013)
This paper reassesses the currently accepted viewpoint that targeting the terminal fields (i.e. striatum) of degenerating nigrostriatal dopamine neurons with neurotrophic factors in Parkinson's disease (PD) is sufficient for achieving an optimal neur
Externí odkaz:
https://doaj.org/article/4e0f8641285a4ca2a7362c915bc96d2f
Autor:
Brian K. Fiske, Simon R.W. Stott, Mart Saarma, Camille Carroll, David Eidelberg, Roger A. Barker, Richard K. Wyse, Patrik Brundin, Amber D. Van Laar, Jamie L. Eberling, David T Dexter, Henri J. Huttunen, Merja H. Voutilainen, Adrian P. Kells, Jeffrey H. Kordower, Eros Bresolin, Alasdair Coles, Leah Mursaleen, Don M. Gash, Karl Kieburtz, Alan L Whone, Howard J. Federoff, A. Jon Stoessl, Sigrid Booms, Lyndsey Isaacs, Massimo S. Fiandaca, Anthony E. Lang, Codrin Lungu, Krystof S. Bankiewicz, Helen Matthews, Anders Björklund
Publikováno v:
Journal of Parkinson's disease, vol 10, iss 3
Barker, R A, Bjorklund, A, Gash, D M, Whone, A, Van Laar, A, Kordower, J H, Bankiewicz, K, Kieburtz, K, Saarma, M, Booms, S, Huttunen, H J, Kells, A, Fiandaca, M S, Stoessl, A J, Eidelberg, D, Federoff, H, Voutilainen, M, Dexter, D T, Eberling, J, Brundin, P, Isaacs, L, Mursaleen, L, Bresolin, E, Carroll, C, Coles, A, Fiske, B, Matthews, H, Lungu, C, Wyse, R K, Stott, S & Lang, A E 2020, ' GDNF and Parkinson's Disease : Where Next? A Summary from a Recent Workshop ', Journal of Parkinson's Disease, vol. 10, no. 3, pp. 875-891 . https://doi.org/10.3233/JPD-202004
Journal of Parkinson's Disease
Barker, R A, Bjorklund, A, Gash, D M, Whone, A, Van Laar, A, Kordower, J H, Bankiewicz, K, Kieburtz, K, Saarma, M, Booms, S, Huttunen, H J, Kells, A, Fiandaca, M S, Stoessl, A J, Eidelberg, D, Federoff, H, Voutilainen, M, Dexter, D T, Eberling, J, Brundin, P, Isaacs, L, Mursaleen, L, Bresolin, E, Carroll, C, Coles, A, Fiske, B, Matthews, H, Lungu, C, Wyse, R K, Stott, S & Lang, A E 2020, ' GDNF and Parkinson's Disease : Where Next? A Summary from a Recent Workshop ', Journal of Parkinson's Disease, vol. 10, no. 3, pp. 875-891 . https://doi.org/10.3233/JPD-202004
Journal of Parkinson's Disease
The concept of repairing the brain with growth factors has been pursued for many years in a variety of neurodegenerative diseases including primarily Parkinson's disease (PD) using glial cell line-derived neurotrophic factor (GDNF). This neurotrophic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88877f6c9a7279991a0d0736af61ec6
https://doi.org/10.3233/jpd-202004
https://doi.org/10.3233/jpd-202004
Autor:
Pia Runeberg-Roos, Richard D. Penn
Publikováno v:
Cell and Tissue Research
The last decade has been a frustrating time for investigators who had envisioned major advances in the treatment of Parkinson’s disease using neurotrophic factors. The first trials of glial cell line–derived neurotrophic factor for treating Parki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79d58781bcf3c4b2155c20ef4d1542b
https://doi.org/10.1007/s00441-020-03256-z
https://doi.org/10.1007/s00441-020-03256-z
Autor:
Arun Kumar Mahato, Yulia Sidorova
Publikováno v:
Cell and Tissue Research
Rearranged during transfection (RET), in complex with glial cell line-derived (GDNF) family receptor alpha (GFRα), is the canonical signaling receptor for GDNF family ligands (GFLs) expressed in both central and peripheral parts of the nervous syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b3c3a02138f9f21fc1fca375e460f9
https://doi.org/10.1007/s00441-020-03227-4
https://doi.org/10.1007/s00441-020-03227-4
Autor:
Zankel, Martin
Die altersabhängige Makuladegeneration (AMD) ist eine komplexe Erkrankung, die zu einer Degeneration retinaler Strukturen führt. Besonders betroffen sind die Photorezeptorzellen und das retinale Pigmentepithel (RPE) der Makula (macula lutea), was z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05aa73af433acc5cfccec23da17180be
Autor:
Ratcliff, Matthew
Growth Differentiation Factor 15 (GDF15) and Neurturin (NRTN) have wide ranging roles in biology, with potential applications in diseases such as diabetes and obesity. As members of the glial cell line derived neurotrophic factor (GDNF) family, both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9695d321283fe8aaff964655a44e423
Autor:
Runeberg-Roos, Pia, Penn, Richard D.
The last decade has been a frustrating time for investigators who had envisioned major advances in the treatment of Parkinson's disease using neurotrophic factors. The first trials of glial cell line-derived neurotrophic factor for treating Parkinson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1593::30d618a138149ccfdd5abe6e302e8897
http://hdl.handle.net/10138/321075
http://hdl.handle.net/10138/321075