Zobrazeno 1 - 10
of 431
pro vyhledávání: '"NRF2/KEAP1"'
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 285-295 (2024)
Context Membranous glomerulonephritis (MGN) is a leading cause of nephrotic syndrome in adults. Diosgenin (DG) has been reported to exert antioxidative and anti-inflammatory effects.Objective To investigate the renoprotective activity of DG in a cati
Externí odkaz:
https://doaj.org/article/e4aa6ca4be49495585f6b100ed142c6d
Autor:
Mohammad Yousefi Zardak, Fatemeh Keshavarz, Ali Mahyaei, Morteza Gholami, Fatemeh Sadat Moosavi, Elham Abbasloo, Farzaneh Abdollahi, Maryam Hossein Rezaei, Elham Madadizadeh, Nasrin Soltani, Fatemeh Bejeshk, Niyan Salehi, Fahimeh Rostamabadi, Fatemeh Bagheri, Mahla Jafaraghae, Mahdiyeh Ranjbar Zeydabadi, Meraj Baghgoli, Gholamreza Sepehri, Mohammad Abbas Bejeshk
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Lung ischemia-reperfusion injury (LIRI) causes oxidative stress, inflammation, and immune system activation. The Nrf2/Keap1/HO-1 pathway is important in cellular defense against these effects. Quercetin, a flavonoid with antioxidant, anti-in
Externí odkaz:
https://doaj.org/article/0c713caf83e14acc81564c003d268a70
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionDiphenyl diselenide (DPDS) ameliorates nephropathy in streptozotocin (STZ)-induced type 1 diabetic rats by inhibiting oxidative stress and inflammatory reactions. However, it has not been clarified whether DPDS alleviates type 1 diabetic
Externí odkaz:
https://doaj.org/article/38aa70716f734640891a317ab83c5e31
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 288, Iss , Pp 117373- (2024)
This study examined how Eucommia ulmoides flavonoids (EUF) protect against intestinal oxidative stress induced by deoxynivalenol (DON) in weaned piglets. Forty weaned piglets were randomly assigned to four dietary groups for a period of 14 days. The
Externí odkaz:
https://doaj.org/article/87a60a956ee44aefa696e855e125c11b
Autor:
Wessam M. Aziz, Samia A. Ahmed, Sylvia E. Shaker, Dalia B. Fayed, Nadia S. Metwally, Heba Shawky
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background & objective : While oxidative stress is the key player driving diabetic nephropathy (DN), firm glycemic control remains the pillar prophylactic measure. Purslane was extensively described as a potent hypoglycemic and hypolipidemic
Externí odkaz:
https://doaj.org/article/1698f46adbc649e0b8d6b825e13ab752
Akademický článek
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Autor:
Xingyu Chen, Wenqian Sun, Yanting Song, Shangong Wu, Shouqi Xie, Wen Xiong, Chengdong Peng, Yu Peng, Zhengxiang Wang, Sovan Lek, Christer Hogstrand, Mette Sørensen, Lei Pan, Dong Liu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 283, Iss , Pp 116947- (2024)
The impact of cadmium (Cd) toxicity on fish liver injury has received much attention in recent years. Currently, autophagy, apoptosis and endoplasmic reticulum stress were reported in Cd exposed fish liver, and if there are other mechanisms (such as
Externí odkaz:
https://doaj.org/article/eccff84cb0b24dfab2197eb94782276d
Autor:
Ragaa SM Kawara, Fatma SM Moawed, Yakout Elsenosi, Hussein Abd Elmaksoud, Esraa S. A. Ahmed, Omayma AR Abo-Zaid
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Melissa officinalis (MO) is a well-known medicinal plant species used in the treatment of several diseases; it is widely used as a vegetable, adding flavour to dishes. This study was designed to evaluate the therapeutic effect of
Externí odkaz:
https://doaj.org/article/bc3d5a2ef225448bb6169798c57171ef
Autor:
Francesca Lazzara, Federica Conti, Pradip K. Sasmal, Shanavas Alikunju, Settimio Rossi, Filippo Drago, Chiara Bianca Maria Platania, Claudio Bucolo
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Diabetic retinopathy is a secondary microvascular complication of diabetes mellitus. This disease progresses from two stages, non-proliferative and proliferative diabetic retinopathy, the latter characterized by retinal abnormal angiogenesis. Pharmac
Externí odkaz:
https://doaj.org/article/a81b5eee337e4d13b952c91027a17ea8
Autor:
Se-Been Jeon, Pil-Soo Jeong, Min Ju Kim, Hyo-Gu Kang, Bong-Seok Song, Sun-Uk Kim, Seong-Keun Cho, Bo-Woong Sim
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Oxidative stress, caused by an imbalance in the production and elimination of intracellular reactive oxygen species (ROS), has been recognized for its detrimental effects on mammalian embryonic development. Luteolin (Lut) has been
Externí odkaz:
https://doaj.org/article/8efe24c70f364e0a8ff6737da86a8e51