Zobrazeno 1 - 10
of 3 005
pro vyhledávání: '"NQO1"'
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background Ischemic stroke (IS) is a major cause of death and disability worldwide. Genetic factors are important risk factors for the development of IS. The quinone oxidoreductase 1 gene (NQO1) has antioxidant, anti-inflammatory, and cytopr
Externí odkaz:
https://doaj.org/article/d628930c5c73409fb5a7130d4f0859b3
Publikováno v:
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 32, Iss 5, Pp 7847-7860 (2024)
Introduction: NRF2 and NQO1 proteins are very important for cell protection; Therefore, the purpose of this research was investigating the effect of resistance training with coenzyme Q10 supplementation on the content of NRF2 and NQO1 proteins in the
Externí odkaz:
https://doaj.org/article/48c748f8fab84b6ca562091cbb81ce02
Autor:
Yunjiang Zhou, Yaxin Chen, Chenyuan Xuan, Xingyan Li, Yingying Tan, Mengdi Yang, Mengran Cao, Chi Chen, Xing Huang, Rong Hu
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103292- (2024)
Chemotherapy has been the standard treatment for liver cancer. However, intrinsic or acquired drug resistance remains a major barrier to successful treatment. At present, the underlying molecular mechanisms of chemoresistance in liver cancer have not
Externí odkaz:
https://doaj.org/article/b8fea6558360431ab9080a37ebe2911e
Autor:
Xin Zhang, Yanan Yang, Hongying Zhao, Zhongqiu Tian, Qing Cao, Yunlong Li, Yajuan Gu, Qinfei Song, Xiumei Hu, Mulan Jin, Xingran Jiang
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 4, Pp n/a-n/a (2024)
Abstract Oxidative stress and the immune microenvironment both contribute to the pathogenesis of esophageal squamous cell carcinoma (ESCC). However, their interrelationships remain poorly understood. We aimed to examine the status of key molecules in
Externí odkaz:
https://doaj.org/article/ad40149acf414b3bb5c8c83d5ff1f37b
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-28 (2024)
Abstract NAD(P)H Quinone Dehydrogenase 1 (NQO1) plays a pivotal role in the regulation of neuronal function and synaptic plasticity, cellular adaptation to oxidative stress, neuroinflammatory and degenerative processes, and tumorigenesis in the centr
Externí odkaz:
https://doaj.org/article/44915be6ad9d472d9d5dd85aed6e1445
Autor:
Soumya Tumbath, Lingxiang Jiang, Xiaoguang Li, Taolan Zhang, Kashif Rafiq Zahid, Ye Zhao, Hao Zhou, Zhijun Yin, Tao Lu, Shu Jiang, Yaomin Chen, Xiang Chen, Yang-Xin Fu, Xiumei Huang
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
NAD(P)H:quinone oxidoreductase 1 (NQO1) is overexpressed in most solid cancers, emerging as a promising target for tumor-selective killing. β-Lapachone (β-Lap), an NQO1 bioactivatable drug, exhibits significant antitumor effects on NQO1-positive ca
Externí odkaz:
https://doaj.org/article/949b1bfe9fef4f57be1db5d9a66f7789
Akademický článek
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Autor:
Hideki Matsumoto, Hideo Sasai, Norio Kawamoto, Masato Katsuyama, Makoto Minamiyama, Satoshi Kuru, Toshiyuki Fukao, Hidenori Ohnishi, the SMON Research Group Members
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Background Subacute myelo‐optico‐neuropathy (SMON) is a neurological disorder associated with the administration of clioquinol, particularly at very high doses. Although clioquinol has been used worldwide, there was an outbreak of SMON i
Externí odkaz:
https://doaj.org/article/1cc8806176c84084a12e00ffc5038dc4
Autor:
Jesús Calahorra, José L. Blaya-Cánovas, Olivia Castellini-Pérez, Ernesto Aparicio-Puerta, Candela Cives-Losada, Jose J.G. Marin, Markel Rementeria, Francisca E. Cara, Araceli López-Tejada, Carmen Griñán-Lisón, Francesco Aulicino, Imre Berger, Juan A. Marchal, Violeta Delgado-Almenta, Sergio Granados-Principal
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116439- (2024)
Triple-negative breast cancer (TNBC) is characterised by its aggressiveness and resistance to chemotherapy, demanding the development of effective strategies against its unique characteristics. Derived from lapacho tree bark, β-lapachone (β-LP) sel
Externí odkaz:
https://doaj.org/article/76400c7a3a124b0abb61e19973f4cfab
Autor:
Taehun Lim, Shivani Rajoriya, Bohyeon Kim, Augustine Natasha, Hyeonjoo Im, Hyun Soo Shim, Junsang Yoo, Jong Woo Kim, Eun-Woo Lee, Hye Jin Shin, Soon Ha Kim, Won-Keun Kim
Publikováno v:
Virus Research, Vol 342, Iss , Pp 199325- (2024)
The COVID-19 pandemic caused by SARS-CoV-2 becomes a serious threat to global health and requires the development of effective antiviral therapies. Current therapies that target viral proteins have limited efficacy with side effects. In this study, w
Externí odkaz:
https://doaj.org/article/808e3e370a074b309e11d12619df0274