Zobrazeno 1 - 10
of 79
pro vyhledávání: '"NPS-2143"'
Autor:
Yu-Hang Li, Zhong-Xin Jiang, Qian Xu, Ting-Ting Jin, Jin-Fang Huang, Xiao Luan, Chong Li, Xin-Yi Chen, Ka-Hing Wong, Xiao-Li Dong, Xiang-Rong Sun
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116518- (2024)
Background: The Calcium-sensing receptor (CaSR) participates in the regulation of gastrointestinal (GI) motility under normal conditions and might be involved in the regulation of GI dysmotility in patients with Parkinson's disease (PD). Methods: CaS
Externí odkaz:
https://doaj.org/article/8f92edcbddfe40078241e842616a1b4f
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 12, Iss 2, Pp 383-388 (2022)
Purpose: Calcium-sensing receptor (CaSR) has been associated with breast cancer metastasis tothe bone. Targeting chemoattractant factors, such as calcium, that are released in response tobone resorption could prevent metastasis and induce apoptosis o
Externí odkaz:
https://doaj.org/article/c234e649324f4922a9ecf9943ddc2dd5
Akademický článek
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Autor:
Thomas B. Duguet, Anastasia Glebov, Asimah Hussain, Shashank Kulkarni, Igor Mochalkin, Timothy G. Geary, Mohammed Rashid, Thomas Spangenberg, Paula Ribeiro
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 13, Iss , Pp 73-88 (2020)
Neglected tropical diseases are of growing worldwide concern and schistosomiasis, caused by parasitic flatworms, continues to be a major threat with more than 200 million people requiring preventive treatment. As praziquantel (PZQ) remains the treatm
Externí odkaz:
https://doaj.org/article/ae57b753674642aabd8528e70e77631a
Akademický článek
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Publikováno v:
Kidney & Blood Pressure Research, Vol 43, Iss 1, Pp 276-286 (2018)
Background/Aims: Renal ischemia/reperfusion (I/R) injury (RI/RI) is a common complication of diabetes, and it may be involved in altering intracellular calcium concentrations at its onset, which can result in inflammation, abnormal lipid metabolism,
Externí odkaz:
https://doaj.org/article/0854badaf8c34d7095b80dc4847073f7
Publikováno v:
Animal Biotechnology. :1-14
This study aimed to test the hypothesis that the calcium-sensing receptor (CaSR) can protect intestinal epithelial barrier integrity and decrease inflammatory response mediated by the Ras-related C3 botulinum toxin substrate 1 (Rac1)/phospholipase C
Publikováno v:
Biochemical and Biophysical Research Communications. 530:651-657
The subversive role of Calcium sensing receptor (CaSR) in cerebral ischemia and traumatic brain injury has been recently reported. Nevertheless, the role of CaSR in early brain injury (EBI) after subarachnoid hemorrhage (SAH) remains unexplored. Usin
Autor:
Rajesh V. Thakker, Caroline M Gorvin, Theingi Aung, Tessa Homfray, Shailini Bahl, Anna K Gluck, Victoria Stokes, Treena Cranston, Brian Shine, Hannah Boon, Fadil M. Hannan, Kate E Lines
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
The Journal of Clinical Endocrinology & Metabolism
The Journal of Clinical Endocrinology & Metabolism
Context Autosomal dominant hypocalcemia types 1 and 2 (ADH1 and ADH2) are caused by germline gain-of-function mutations of the calcium-sensing receptor (CaSR) and its signaling partner, the G-protein subunit α 11 (Gα 11), respectively. More than 70
Publikováno v:
Foodfunction. 12(19)
Although soybean protein is the major component in livestock feeds, its effect on pigs' appetites is largely unknown. Recently, the importance of gut nutrient-sensing for appetite modulation by regulating anorectic gut hormone release has been recogn