Zobrazeno 1 - 10
of 69
pro vyhledávání: '"NOTCH1 mutation"'
Autor:
Thi Oanh Bui, Eurydice Angeli, Morad El Bouchtaoui, Guillaume Gapihan, Van Tu Dao, Justine Paris, Christophe Leboeuf, Michael Soussan, Patrick Villarese, Marianne Ziol, Emmanuel Van Glabeke, Thi Huong Le, Jean-Paul Feugeas, Anne Janin, Guilhem Bousquet
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-6 (2023)
Abstract Background Clear-cell renal cell carcinomas (ccRCCs) are malignant tumors with high metastatic potential and resistance to treatments occurs almost constantly. Compared to primary tumors, there are still limited genomic data that has been ob
Externí odkaz:
https://doaj.org/article/eca1bd952c984b32adee25682a00986b
Autor:
Estevão Carlos Silva Barcelos, Chiara Rompietti, Francesco Maria Adamo, Erica Dorillo, Filomena De Falco, Beatrice Del Papa, Stefano Baldoni, Manuel Nogarotto, Angela Esposito, Silvia Capoccia, Clelia Geraci, Daniele Sorcini, Arianna Stella, Roberta Arcaleni, Valentina Tini, Flávia Imbroisi Valle Errera, Emanuela Rosati, Paolo Sportoletti
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionConstitutive activation of NOTCH1-wild-type (NT1-WT) signaling is associated with poor outcomes in chronic lymphocytic leukemia (CLL), and NOTCH1 mutation (c.7541_7542delCT), which potentiates NOTCH1 signaling, worsens the prognosis. Howe
Externí odkaz:
https://doaj.org/article/42a87a28abc246f28270a9eea157bbfb
Autor:
Jennifer Yuying Chen, BS, Elizabeth Keiser, MD, Philip LeBoit, MD, Iwei Yeh, MD, PhD, Maria L. Wei, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 21, Iss , Pp 49-51 (2022)
Externí odkaz:
https://doaj.org/article/4bb11424c8b847fcbb4aa2b129154c67
Autor:
Xiao-yang Gong, Hai-bin Chen, Li-qing Zhang, Dong-sheng Chen, Wang Li, Dong-hui Chen, Jin Xu, Han Zhou, Le-le Zhao, Yun-jie Song, Ming-zhe Xiao, Wang-long Deng, Chuang Qi, Xue-rong Wang, Xi Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPatients with early-stage laryngeal cancer, even stage T1-2N0, are at considerable risk of recurrence and death. The genetic and immunologic characteristics of recurrent laryngeal cancer remain unclear.MethodsA total of 52 T1-2N0 laryngeal
Externí odkaz:
https://doaj.org/article/6ba630dd5c504c1ea8ba532fa07f7aac
Autor:
Stefano Baldoni, Beatrice Del Papa, Filomena De Falco, Erica Dorillo, Carlo Sorrentino, Chiara Rompietti, Francesco Maria Adamo, Manuel Nogarotto, Debora Cecchini, Elena Mondani, Estevao Carlos Silva Barcelos, Lorenzo Moretti, Maria Grazia Mameli, Bianca Fabi, Daniele Sorcini, Arianna Stella, Raffaella Giancola, Francesco Guardalupi, Francesca Ulbar, Sara Plebani, Valerio Guarente, Emanuela Rosati, Marta Di Nicola, Michele Marchioni, Mauro Di Ianni, Paolo Sportoletti
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
NOTCH1 mutations and deregulated signal have been commonly found in chronic lymphocytic leukemia (CLL) patients. Whereas the impact of NOTCH1 mutations on clinical course of CLL has been widely studied, the prognostic role of NOTCH1 activation in CLL
Externí odkaz:
https://doaj.org/article/bf604ad42c61485b9c589e15303f6899
Akademický článek
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Autor:
Mauro Di Ianni, Stefano Baldoni, Beatrice Del Papa, Patrizia Aureli, Erica Dorillo, Filomena De Falco, Elisa Albi, Emanuela Varasano, Ambra Di Tommaso, Raffaella Giancola, Patrizia Accorsi, Gianluca Rotta, Chiara Rompietti, Estevão Carlos Silva Barcelos, Antonio Francesco Campese, Paolo Di Bartolomeo, Isabella Screpanti, Emanuela Rosati, Franca Falzetti, Paolo Sportoletti
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
To investigate chronic lymphocytic leukemia (CLL)-initiating cells, we assessed NOTCH1 mutation/expression in hematopoietic stem cells (HSCs). In NOTCH1-mutated CLL, we detected subclonal mutations in 57% CD34+/CD38− HSCs. NOTCH1 mutation was prese
Externí odkaz:
https://doaj.org/article/22cb5b5b90a04145889dadc04b8f6e35
Publikováno v:
Romanian Journal of Laboratory Medicine, Vol 22, Iss 4, Pp 507-513 (2014)
În literatura de specialitate sunt prezentate foarte puține cazuri de leucemie limfocitară cronică (LLC), care debutează cu hiperleucocitoză extremă. Descriem cazul unei femei în vârstă de 66 ani, care se prezintă cu hiperleucocitoză extr
Externí odkaz:
https://doaj.org/article/07ede6d839fb4b6a87c456cdc903e0db
Akademický článek
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Akademický článek
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