Výsledky vyhledávání - "NORIO NAGAMOTO"

Synthesis and anti-cholinergic activity of aminoalkyl 2-cyclic amino-2-(1,2-benzisoxazol-3-yl)acetates and their quaternary ammonium salts

Autor: Haruki Nishimura, Norio Nagamoto, Shunsuke Naruto, Toshifumi Suzuki, Hitoshi Uno, Hiroyuki Mizuta

Publikováno v: European Journal of Medicinal Chemistry. 22:209-212

A series of aminoalkyl 2-cyclic amino-2-(1,2-benzisoxazol-3-yl)acetates 1 and 2 and their quaternary ammonium derivatives 3 and 4 has been prepared and tested for anti-cholinergic activity. Among these compounds, 1-alkyl-1-methyl-4-[2-cyclic amino-2-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67f03e51722f88b2842577ce5227fb03
https://doi.org/10.1016/0223-5234(87)90051-1

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3-Hydroxypyrroles. III. Synthesis and tautomerism of N-alkyl-3-hydroxypyrroles

Autor: Norio Nagamoto, Takashi Yokota, Kazuyo Yamada, Tetsuaki Tanaka, Takefumi Momose

Publikováno v: Chemical and Pharmaceutical Bulletin. 27:1448-1453

Syntheses of 3-hydroxypyrroles (4-oxo-2-pyrrolines) (1b-1d) bearing no substituents on the ring carbon and of 3-hydroxypyrrole-4-carboxylates (2-4) with no substituents at C-5 were accomplished ; the former by hydrogenolysis of the benzyl esters (6b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::015d693cbef245592f80ff7681a700a7
https://doi.org/10.1248/cpb.27.1448

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3-Hydroxypyrroles. I. A general synthetic route to 4,5-unsubstituted alkyl 3-hydroxpyrrole-2-carboxylates

Autor: Tetsuaki Tanaka, Norio Nagamoto, Takefumi Momose, Takashi Yokota, Kazuyo Yamada

Publikováno v: Chemical and Pharmaceutical Bulletin. 26:2224-2232

The synthesis of 4, 5-unsubstituted alkyl 3-hydroxypyrrole-2-carboxylates was described. An equimolar mixture of glycine esters (6) and diethyl ethoxymethylenemalonate (7) gave the condensation products (8) with liberation of ethanol. 3-Hydroxypyrrol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77d310c9b944a5ffce576c90b12f4005
https://doi.org/10.1248/cpb.26.2224

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3-Hydroxypyrroles. II. The reaction of 4,5-unsubstituted alkyl 3-hydroxypyrrole-2-carboxylates with some electrophiles

Autor: Tetsuaki Tanaka, Kazuyo Yamada, Takashi Yokota, Norio Nagamoto, Takefumi Momose

Publikováno v: Chemical and Pharmaceutical Bulletin. 26:3521-3529

The reaction of alkyl 3-hydroxypyrrole-2-carboxylates (1) with some electrophiles was investigated. The alkylation of 1c occurred at the O and C-2 position as in the case of usual β-keto esters. An N-substituted 3-hydroxypyrrole-2-carboxylate (1e) r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d65443d3a908c0635edb977c5143624
https://doi.org/10.1248/cpb.26.3521

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Photolysis of 4-oxo-4H-benzisoxazolo(2,3-a)pyridines

Autor: Hiroyuki Mizuta, T. Yoshida, Norio Nagamoto, Shunsuke Naruto, Hitoshi Uno

Publikováno v: Chemical and Pharmaceutical Bulletin. 30:3421-3423

Photolysis of 4-oxo-4H-benzisoxazolo [2, 3-a] pyridines (1a-d) and their C1-monobromides (4a-d) afforded benzofuro [3, 2-b] pyridines (2a-d) via initial N5-O6 bond fission. However, similar photolysis of 9-methoxy-4-oxo-4H-benzisoxazolo [2, 3-a] pyri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ce6966411b7f05b25b9002248272e43
https://doi.org/10.1248/cpb.30.3421

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ChemInform Abstract: 3-HYDROXYPYRROLES. I. A GENERAL SYNTHETIC ROUTE TO 4,5-UNSUBSTITUTED ALKYL 3-HYDROXYPYRROLE-2-CARBOXYLATES

Autor: Takefumi Momose, Takashi Yokota, Kazuyo Yamada, Tetsuaki Tanaka, Norio Nagamoto

Publikováno v: Chemischer Informationsdienst. 9

Die Glycinester (II) kondensieren mit dem Malonsaureester (I) zu den Enaminen (III), die zu den substituierten Pyrrolen (IV) cyclisiert werden.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ec4dd826587a6da72f4e275284b217f
https://doi.org/10.1002/chin.197848219

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