Zobrazeno 1 - 10
of 130
pro vyhledávání: '"NORIE ARAKI"'
Autor:
Takumi Yamamoto, Arisu Furukawa, Yue Zhou, Nobuaki Kono, Shojiro Kitajima, Hiroto Ohguchi, Yawara Kawano, Shingo Ito, Norie Araki, Sumio Ohtsuki, Takeshi Masuda
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111399- (2024)
Summary: Lenalidomide (LEN) is commonly used as an effective therapeutic agent for multiple myeloma (MM). However, in some patients, primary resistance to LEN is observed, the mechanisms of which remain poorly understood. In this study, we combined a
Externí odkaz:
https://doaj.org/article/591a78604d6e44db8412ba7e9e8612a2
Autor:
Chutima Talabnin, Thanawat Trasaktaweesakul, Pitchanun Jaturutthaweechot, Pundit Asavaritikrai, Dusit Kongnawakun, Atit Silsirivanit, Norie Araki, Krajang Talabnin
Publikováno v:
PeerJ, Vol 12, p e16785 (2024)
Background Changes in protein glycosylation have been reported in various diseases, including cancer; however, the consequences of altered glycosylation in meningiomas remains undefined. We established two benign meningioma cell lines—SUT-MG12 and
Externí odkaz:
https://doaj.org/article/04c3782afa0e479da4bd90f7264dc89e
Autor:
Tatsuya Yoshizawa, Yoshifumi Sato, Shihab U. Sobuz, Tomoya Mizumoto, Tomonori Tsuyama, Md. Fazlul Karim, Keishi Miyata, Masayoshi Tasaki, Masaya Yamazaki, Yuichi Kariba, Norie Araki, Eiichi Araki, Shingo Kajimura, Yuichi Oike, Thomas Braun, Eva Bober, Johan Auwerx, Kazuya Yamagata
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Sirtuins have been reported to positively regulate brown adipose tissue thermogenesis. Here the authors report that brown adipocytic SIRT7 suppresses whole-body energy expenditure and thermogenesis in mice, potentially by attenuating batokine gene ex
Externí odkaz:
https://doaj.org/article/7b51c06d17574f72b35f0b3884a3c7fe
Autor:
Takao Kitagawa, Daiki Kobayashi, Byron Baron, Hajime Okita, Tatsuo Miyamoto, Rie Takai, Durga Paudel, Tohru Ohta, Yoichi Asaoka, Masayuki Tokunaga, Koji Nakagawa, Makoto Furutani-Seiki, Norie Araki, Yasuhiro Kuramitsu, Masanobu Kobayashi
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0269077 (2022)
Ewing's sarcoma is the second most common bone malignancy in children or young adults and is caused by an oncogenic transcription factor by a chromosomal translocation between the EWSR1 gene and the ETS transcription factor family. However, the trans
Externí odkaz:
https://doaj.org/article/d512cd9250084159b5339187fcfaf8d2
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
In the endoplasmic reticulum-associated degradation system of plant and animal cells, high-mannose type free N-glycans (HMT-FNGs) are produced from misfolded glycoproteins prior to proteasomal degradation, and two enzymes, cytosolic peptide:N-glycana
Externí odkaz:
https://doaj.org/article/2bf6eb38929144498ce3437baa782ac6
Autor:
Mayumi Hirayama, Fan-Yan Wei, Takeshi Chujo, Shinya Oki, Maya Yakita, Daiki Kobayashi, Norie Araki, Nozomu Takahashi, Ryoji Yoshida, Hideki Nakayama, Kazuhito Tomizawa
Publikováno v:
Cell Reports, Vol 31, Iss 1, Pp - (2020)
Summary: N6-Methyladenosine (m6A) modification is the major chemical modification in mRNA that controls fundamental biological processes, including cell proliferation. Herein, we demonstrate that fat mass and obesity-associated (FTO) demethylates m6A
Externí odkaz:
https://doaj.org/article/b31306cd90024b878954550d4a52dce1
Autor:
Masatoshi Fukuda, Tatsuya Yoshizawa, Md. Fazlul Karim, Shihab U. Sobuz, Wataru Korogi, Daiki Kobayasi, Hiroki Okanishi, Masayoshi Tasaki, Katsuhiko Ono, Tomohiro Sawa, Yoshifumi Sato, Mami Chirifu, Takeshi Masuda, Teruya Nakamura, Hironori Tanoue, Kazuhisa Nakashima, Yoshihiro Kobashigawa, Hiroshi Morioka, Eva Bober, Sumio Ohtsuki, Yuriko Yamagata, Yukio Ando, Yuichi Oike, Norie Araki, Shu Takeda, Hiroshi Mizuta, Kazuya Yamagata
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
SP7/Osterix is a transcription factor involved in osteoblast differentiation. Here, the authors show that Sirtuin 7 activates Osterix posttranslationally by regulating its lysine acylation, and that mice lacking Sirtuin 7 in osteoblasts show reduced
Externí odkaz:
https://doaj.org/article/5d154c78ddfa43f09911b245d2d21134
Autor:
Akiko Niibori-Nambu, Uichi Midorikawa, Souhei Mizuguchi, Takuichiro Hide, Minako Nagai, Yoshihiro Komohara, Megumi Nagayama, Mio Hirayama, Daiki Kobayashi, Nobuyuki Tsubota, Tatsuya Takezaki, Keishi Makino, Hideo Nakamura, Motohiro Takeya, Junichi Kuratsu, Norie Araki
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e59558 (2013)
Glioma initiating cells (GICs) are considered responsible for the therapeutic resistance and recurrence of malignant glioma. To clarify the molecular mechanism of GIC maintenance/differentiation, we established GIC clones having the potential to diff
Externí odkaz:
https://doaj.org/article/29e00a437c104327844d8651cc075cb4
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51242 (2012)
We previously reported that protein kinase D2 (PKD2) in T cells is promptly activated after T-cell receptor (TCR) stimulation and involved in the activation of interleukin-2 promoter and T cell death, and that one of its candidate substrate is SET pr
Externí odkaz:
https://doaj.org/article/7ca1c1b72db241a88613e2e55e0aa0c6
Autor:
Orasa Panawan, Atit Silsirivanit, Chih‐Hsiang Chang, Siyaporn Putthisen, Piyanard Boonnate, Taro Yokota, Yuki Nishisyama‐Ikeda, Marutpong Detarya, Kanlayanee Sawanyawisuth, Worasak Kaewkong, Kanha Muisuk, Sukanya Luang, Kulthida Vaeteewoottacharn, Ryosho Kariya, Hiromu Yano, Yoshihiro Komohara, Kunimasa Ohta, Seiji Okada, Sopit Wongkham, Norie Araki
Publikováno v:
Cancer Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5700e655fca40aa3098804266f9dab9d
https://doi.org/10.1111/cas.15812
https://doi.org/10.1111/cas.15812