Zobrazeno 1 - 10
of 14
pro vyhledávání: '"NOESY, nuclear Overhauser enhancement spectroscopy"'
Autor:
Alain Fournier, Bruce G. Allen, Tuan Anh Hoang, Terence E. Hébert, Ryan D. Martin, Alfonso Carotenuto, Juliana C. C. Dallagnol, Myriam Létourneau, Hassan Nassour, David Chatenet, Étienne Billard, Jason C. Tanny, Ettore Novellino
Publikováno v:
The Journal of Biological Chemistry
Over the last decade, the urotensinergic system, composed of one G protein-coupled receptor and two endogenous ligands, has garnered significant attention as a promising new target for the treatment of various cardiovascular diseases. Indeed, this sy
Autor:
Magdaléna Krejčíková, Pavel Brázda, Eliška Šmiřáková, Karel Kubíček, Aiste Kasiliauskaite, Robert Vácha, Richard Štefl, Tomáš Klumpler
Publikováno v:
Journal of Molecular Biology
Transcription elongation factor Spt6 associates with RNA polymerase II (RNAP II) via a tandem SH2 (tSH2) domain. The mechanism and significance of the RNAP II–Spt6 interaction is still unclear. Recently, it was proposed that Spt6-tSH2 is recruited
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 56-63 (2015)
FEBS Open Bio
FEBS Open Bio
Highlights • Nearly complete backbone assignments for monomeric SOD1 were obtained. • Monomeric SOD1 is unstructured in 9 M urea. • Zn2+-binding to monomeric SOD1 occurs through diffuse coordination to most His residues. • The binding geometr
Autor:
Simon D. Taylor-Robinson, Asmaa Gomaa, Jin Un Kim, Elaine Holmes, Nimzing G. Ladep, Imam Waked, Mary M.E. Crossey, Mohamed I.F. Shariff, I. Jane Cox, Edith N. Okeke, Edmund Banwat, Roger Williams
BACKGROUND/AIMS: Previous studies have observed disturbances in the (1)H nuclear magnetic resonance (NMR) blood spectral profiles in malignancy. No study has metabotyped serum or plasma of hepatocellular carcinoma (HCC) patients from two diverse popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c3f0cc42df3b36fe53de2e5da25974
http://hdl.handle.net/10044/1/49572
http://hdl.handle.net/10044/1/49572
Autor:
Yu-Nan Liu, Ping-Chiang Lyu, Min-Fang Shih, Chao-Sheng Cheng, Shang-Te Danny Hsu, Dian-Jiun Chen, Tien-Sheng Tseng
Publikováno v:
Biochemical Journal
Drosophila melanogaster crammer is a novel cathepsin inhibitor that is involved in LTM (long-term memory) formation. The mechanism by which the inhibitory activity is regulated remains unclear. In the present paper we have shown that the oligomeric s
Autor:
Igor L. Barsukov, Mohamed Bouaouina, Iain D. Campbell, David A. Calderwood, David S. Harburger, Bipin Patel, Benjamin T. Goult, Nicholas J. Anthis, David R. Critchley, Gordon C. K. Roberts, Neil Bate
Publikováno v:
Journal of Molecular Biology
The integrin family of heterodimeric cell adhesion molecules exists in both low- and high-affinity states, and integrin activation requires binding of the talin FERM (four-point-one, ezrin, radixin, moesin) domain to membrane-proximal sequences in th
Autor:
P. Raj Pokkuluri, Carlos A. Salgueiro, Joana M. Dantas, Telma Simões, Yuri Y. Londer, Leonor Morgado
Publikováno v:
Bioscience Reports, Vol 33, Iss 1, p e00002 (2012)
Bioscience Reports
Bioscience Reports
The bacterium Gs (Geobacter sulfurreducens) is capable of oxidizing a large variety of compounds relaying electrons out of the cytoplasm and across the membranes in a process designated as extracellular electron transfer. The trihaem cytochrome PpcA
Autor:
Paul Rösch, Olivia Hartl-Spiegelhauer, Wilfried Schwab, Christian Seutter von Loetzen, Kristian Schweimer
Publikováno v:
Bioscience Reports, Vol 32, Iss 6 (2012)
Bioscience Reports
Bioscience Reports
The PR10 family protein Fra a 1E from strawberry (Fragaria x ananassa) is down-regulated in white strawberry mutants, and transient RNAi (RNA interference)-mediated silencing experiments confirmed that Fra a 1 is involved in fruit pigment synthesis.
Autor:
Milo B. Fasken, Murray Stewart, Anita H. Corbett, Michelle T. Harreman, David Neuhaus, Richard P. Grant, Seth M. Kelly, Ji-Chun Yang, Neil J. Marshall
Publikováno v:
Journal of Molecular Biology
Nuclear abundant poly(A) RNA-binding protein 2 (Nab2) is an essential yeast heterogeneous nuclear ribonucleoprotein that modulates both mRNA nuclear export and poly(A) tail length. The N-terminal domain of Nab2 (residues 1–97) mediates interactions
Publikováno v:
FEBS Letters. (3):293-298
The alpha-ImI conotoxin, a selective potent inhibitor of the mammalian neuronal alpha7 nicotinic acetylcholine receptor (n-AchR), was shown by point mutation or by L-alanine scanning to display two regions essential for bioactivity: the active site A