Zobrazeno 1 - 10
of 51
pro vyhledávání: '"NOD2 receptor"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
According to the WHO, cancer is the second leading cause of death in the world. This is an important global problem and a major challenge for researchers who have been trying to find an effective anticancer therapy. A large number of newly discovered
Externí odkaz:
https://doaj.org/article/5910fc9e48f94fe2b193355e8b70e4b6
Autor:
Adham Fani Maleki, Giulia Cisbani, Marie-Michèle Plante, Paul Préfontaine, Nataly Laflamme, Jean Gosselin, Serge Rivest
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background Muramyl dipeptide (MDP) is a component derived from minimal peptidoglycan motif from bacteria, and it is a ligand for the NOD2 receptor. Peripheral administration of MDP converts Ly6Chigh into Ly6Clow monocytes. Previously, we hav
Externí odkaz:
https://doaj.org/article/e20f26949cc14b939460d418c70ef07e
Autor:
Anne-Julie Lessard, Manon LeBel, Benoit Egarnes, Paul Préfontaine, Peter Thériault, Arnaud Droit, Alexandre Brunet, Serge Rivest, Jean Gosselin
Publikováno v:
Cell Reports, Vol 20, Iss 8, Pp 1830-1843 (2017)
The signals that regulate the fate of circulating monocytes remain unknown. In the present study, we demonstrate that triggering of the NOD2 receptor by muramyl dipeptide (MDP) converts inflammatory Ly6Chigh monocytes into patrolling Ly6Clow monocyte
Externí odkaz:
https://doaj.org/article/832585c9c1464d0396900875e3d1d1e7
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Sep . 112(37), 11660-11665.
Externí odkaz:
https://www.jstor.org/stable/26465074
Autor:
Marian M. J. H. P. Willems, Gijs G. Zom, Nico Meeuwenoord, Ferry A. Ossendorp, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée, Dmitri V. Filippov
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 1445-1453 (2014)
The covalent attachment of an innate immune system stimulating agent to an antigen can provide active vaccine modalities capable of eliciting a potent immune response against the incorporated antigen. Here we describe the design, automated synthesis
Externí odkaz:
https://doaj.org/article/8ba07bdc89314fe592a28a8770e53ec6
Autor:
Bizjak, Špela
Imunski sistem predstavlja glavno obrambo človeškega organizma pred patogeni, zato je hitro prepoznavanje tujkov in njihova odstranitev ključna za uspešen odziv. Imunske celice prepoznajo s patogeni povezane molekulske vzorce (PAMP) preko recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3505::143d43a4d52012344fb1684a3453b3d9
https://hdl.handle.net/20.500.12556/RUL-137214
https://hdl.handle.net/20.500.12556/RUL-137214
Autor:
Paurević, Marija
U disertaciji je opisana sinteza novih desmuramil-peptida s ugrađenim adamantanskim aminokiselinama te manoznih derivata peptida s ciljem istraživanja njihovih imunomodulacijskih svojstava i strukturnih karakteristika. Sinteza peptida i glikopeptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3908::346ff129c720a6ef417ac6d1529cb1d3
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:9778
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:9778
Publikováno v:
Organicbiomolecular chemistry. 19(32)
Nucleotide-binding oligomerization domain 2 (NOD2) is an intracellular receptor that recognizes the bacterial peptidoglycan fragment, muramyl dipeptide (MDP). Our group has synthesized and biologically evaluated desmuramyl peptides containing adamant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3582fec21fff37defc935d6dc1f72a5d
https://pubmed.ncbi.nlm.nih.gov/34095941
https://pubmed.ncbi.nlm.nih.gov/34095941
Muramyl dipeptide (MDP, N-acetylmuramyl-L-alanyl- D-isoglutamine) is the smallest peptidoglycan fragment with adjuvant activity. MDP acts as a pathogen-associated molecular pattern and activates the NOD2 receptor. We have designed and prepared MDP an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::f74883c3af7e0bec66394c0c099b1d6a
https://www.bib.irb.hr/1154960
https://www.bib.irb.hr/1154960
Muramyl dipeptide (MDP, N-acetylmuramyl-L-alanyl- D-isoglutamine) is a conserved fragment of a bacterial cell walls and the smallest peptidoglycan fragment competent to trigger the immune response. MDP binds to NOD2 (nucleotide binding and oligomeriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::e4cb034cd87c0bfad756efe35d59f200
https://www.bib.irb.hr/1154968
https://www.bib.irb.hr/1154968