Zobrazeno 1 - 10
of 1 425
pro vyhledávání: '"NOD-like receptors"'
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107411- (2024)
Despite considerable improvements in understanding the biology of glioblastoma (GB), it still remains the most lethal type of brain tumor in adults. The role of innate immune cells in the development of GB was recently described. In particular, the t
Externí odkaz:
https://doaj.org/article/74451c2136384b60bf5269783fa2a188
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116724- (2024)
Metabolic dysfunction-associated steatotic liver disease (MASLD) has become one of the most prevalent liver diseases worldwide, and its occurrence is strongly associated with obesity, insulin resistance (IR), genetics, and metabolic stress. Ranging f
Externí odkaz:
https://doaj.org/article/8f3507d9d486418a812442df83729b7d
Autor:
O. P. Lebedeva, V. M. Ivannikova, I. O. Zhukova, O. N. Kozarenko, O. B. Altukhova, S. P. Pakhomov, M. I. Churnosov
Publikováno v:
Акушерство, гинекология и репродукция, Vol 17, Iss 5, Pp 554-564 (2023)
Nucleotide-binding oligomerization domain-like receptors (NOD-like receptors) are cytosolic signaling receptors of innate immune cells recognizing ligands derived from bacteria, viruses, fungi and protozoa. They can initiate apoptosis and pro-inflamm
Externí odkaz:
https://doaj.org/article/d9cc7834f6eb474fad72e75dc3ba312c
Publikováno v:
Pathogens, Vol 13, Iss 7, p 561 (2024)
Influenza virus possesses an RNA genome of single-stranded, negative-sensed, and segmented configuration. Influenza virus causes an acute respiratory disease, commonly known as the “flu” in humans. In some individuals, flu can lead to pneumonia a
Externí odkaz:
https://doaj.org/article/77ff552fed964a83ae89c691df71f7fe
Publikováno v:
Biomedical Journal, Vol 47, Iss 1, Pp 100655- (2024)
Nod-like receptors (NLRs) are innate immune receptors that play a key role in sensing components from pathogens and from damaged cells or organelles. NLRs form signaling complexes that can lead to activation of transcription factors or effector caspa
Externí odkaz:
https://doaj.org/article/53452d5c30f945b1983c24e7f5afbddf
Publikováno v:
Biomedical Journal, Vol 47, Iss 1, Pp 100635- (2024)
NLRX1 is a member of the of the Nod-like receptor (NLR) family, and it represents a unique pattern recognition molecule (PRM) as it localizes to the mitochondrial matrix in resting conditions. Over the past fifteen years, NLRX1 has been proposed to r
Externí odkaz:
https://doaj.org/article/7b83b3daae22408cb5c490b114c21e9a
Publikováno v:
Biomedical Journal, Vol 47, Iss 1, Pp 100637- (2024)
It has long been appreciated that cues from the innate immune system orchestrate downstream adaptive immune responses. Although previous work has focused on the roles of Toll-like receptors in this regard, relatively little is known about how Nod-lik
Externí odkaz:
https://doaj.org/article/a7d006034a1e456292fb5dc39c53310c
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Inflammasomes, composed of the nucleotide-binding oligomerization domain(NOD)-like receptors (NLRs), are immune-functional protein multimers that are closely linked to the host defense mechanism. When NLRs sense pathogen-associated molecular patterns
Externí odkaz:
https://doaj.org/article/19c90f9466bd4ba28b0f17dbd4370ec0