Zobrazeno 1 - 3
of 3
pro vyhledávání: '"NOD, nucleotide oligomerisation domain"'
Autor:
Emmerich, Christoph H., Bakshi, Siddharth, Kelsall, Ian R., Ortiz-Guerrero, Juanma, Shpiro, Natalia, Cohen, Philip
Publikováno v:
Biochemical and Biophysical Research Communications
We have reported previously that activation of the MyD88-signaling network rapidly induces the formation of hybrid ubiquitin chains containing both Lys63-linked and Met1-linked ubiquitin (Ub) oligomers, some of which are attached covalently to Interl
Publikováno v:
Febs Letters
Highlights • NOD2 SNPs that cause Blau syndrome cluster in two regions of the NACHT. • The ATP/Mg2+ binding pocket cluster are likely to dysregulate ATP hydrolysis. • SNPs in helical domain 1 are predicted to influence receptor autoinhibition.
Autor:
Rhiannon, Parkhouse, Joseph P, Boyle, Sophie, Mayle, Kovilen, Sawmynaden, Katrin, Rittinger, Tom P, Monie
Publikováno v:
Febs Letters
Highlights • We have studied the interaction between NOD2 and CARD9. • The NACHT domain and CARD–NACHT linker of NOD2 are crucial for the interaction. • The CARD domains of NOD2 and CARD9 do not directly interact.
NOD2 activation by mura
NOD2 activation by mura