Výsledky vyhledávání - "NOBUJI MAEDA"

Acceleration of erythrocyte aggregation with in vivo aging

Autor: Nobuji Maeda, Masahiko Seike, Takashi Nakajima, Youji Suzuki, Takeshi Shiga

Publikováno v: Clinical Hemorheology and Microcirculation. 9:909-922

This paper presents the studies on the erythrocyte aggregation of density-fractionated human erythrocytes, and demonstrates the accelerated aggregation of aged cells at low shear rate. Furthermore, the functional, biochemical and cell geometrical cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee4f0cba4d60466a0ae28b292a110335
https://doi.org/10.3233/ch-1989-9603

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Peculiar flow patterns of RBCs suspended in viscous fluids and perfused through a narrow tube (25 μm)

Autor: Nobuji Maeda, Hiromi Sakai, Eishun Tsuchida, Shinji Takeoka, Atsushi Sato, Naoto Okuda

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 297:H583-H589

Red blood cells (RBCs) generally deform to adopt a parachute-like, torpedo-like, or other configuration to align and flow through a capillary that is narrower than their major axis. As described herein, even in a narrow tube (25 microm) with diameter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65acea772dd62ec579a10a9be0ac5aa6
https://doi.org/10.1152/ajpheart.00352.2009

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Reelin signals survival through Src-family kinases that inactivate BAD activity

Autor: Nobutaka Ohkubo, Tetsuro Miki, Atsuyuki Morishima, Yoji Suzuki, Noriaki Mitsuda, Nobuji Maeda, Michael P. Vitek

Publikováno v: Journal of Neurochemistry. 103:820-830

Reelin plays an important role in the migration of embryonic neurons, but its continuing presence suggests additional functions in the brain. We now report a novel function where reelin protects P19 embryonal cells from apoptosis during retinoic acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57b4e4599ac70a78e5704cf60227aad9
https://doi.org/10.1111/j.1471-4159.2007.04804.x

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Neutrophil-activating activity and platelet-activating factor synthesis in cytokine-stimulated endothelial cells: Reduced activity in growth-arrested cells

Autor: Haruo Shintaku, Kazuo Kobayashi, Yoshiki Nishizawa, Tatsuji Takahashi, Nagatoshi Fujiwara, Masaaki Inaba, Nobuji Maeda, Seiichi Kitagawa, Fumihiko Hato

Publikováno v: Microvascular Research. 73:29-34

The reactivity of endothelial cells (ECs) to proinflammatory cytokines is critically important for the pathogenesis of vascular diseases. Here, we studied functional alterations of human ECs during culture under a confluent condition; i.e., the alter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e198acbfcc74ace30b62afc84894963a
https://doi.org/10.1016/j.mvr.2006.08.002

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Prevention of Ischemic Neuronal Death by Intravenous Infusion of a Ginseng Saponin, Ginsenoside Rb1, That Upregulates Bcl-xL Expression

Autor: Kohji Sato, Keiichi Samukawa, Noriaki Mitsuda, Masahiro Sakanaka, Ryuji Hata, Pengxiang Zhu, Bo Zhang, Lihua Yang, Hiroko Fujita, Junya Tanaka, Nobuji Maeda, Tong Chun Wen

Publikováno v: Journal of Cerebral Blood Flow & Metabolism. 26:708-721

Almost all agents that exhibit neuroprotection when administered into the cerebral ventricles are ineffective or much less effective in rescuing damaged neurons when infused into the blood stream. Search for an intravenously infusible drug with a pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dbcce62164f677d4296f291bf25be2
https://doi.org/10.1038/sj.jcbfm.9600225

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Electrostatic Repulsion among Red Blood Cells: Observed by Macromolecule-Induced Cell Aggregation and Flow Behavior of the Cells in Microtubes

Autor: Nobuji Maeda, Yoji Suzuki

Publikováno v: Nihon Reoroji Gakkaishi. 33:125-133

Electrostatic repulsive force among human red blood cells (RBCs) was observed by macromolecules-induced RBC aggregation and RBC flow behavior in narrow tube, by reducing the sialic acid content of RBCs with neuraminidase. The electrophoretic mobility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b41a572a307b52535c9ee2acbaeaa1b
https://doi.org/10.1678/rheology.33.125

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NFκB Regulates Plasma Apolipoprotein A-I and High Density Lipoprotein Cholesterol through Inhibition of Peroxisome Proliferator-activated Receptor α

Autor: Tetsuro Miki, Atsuyuki Morishima, Noriaki Mitsuda, Nobutaka Ohkubo, Nobuji Maeda

Publikováno v: Journal of Biological Chemistry. 278:38188-38193

The levels of plasma HDL cholesterol and apoA-I in NFkappaB p50 subunit-deficient mice were significantly higher than those in wild-type mice under regular and high fat diets, without any significant difference in the level of total cholesterol. To e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae308890dd39dc51b298b7332db8ac3d
https://doi.org/10.1074/jbc.m306336200

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Changes of RBC aggregation in oxygenation-deoxygenation: pH dependency and cell morphology

Autor: Yoji Suzuki, Nobuji Maeda, Iwona Cicha, Norihiko Tateishi

Publikováno v: Scopus-Elsevier

The effects of the oxygenation-deoxygenation process on red blood cell (RBC) aggregation were examined in relation to morphological changes in RBCs and the contribution of CO2. A low-shear rheoscope was used to measure the rate of rouleaux (one-dimen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdb65a3e698a7c665d0a1d08099fbec
https://doi.org/10.1152/ajpheart.01030.2002

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