Zobrazeno 1 - 10
of 1 115
pro vyhledávání: '"NNK"'
Autor:
Xuelei Liu, Jingjing Wang, Ziyi Yang, Qipeng Xie, Xinqi Diao, Xiaoyan Yao, Shirui Huang, Ruifan Chen, Yunping Zhao, Tengda Li, Minghua Jiang, Zhefeng Lou, Chuanshu Huang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 286, Iss , Pp 117157- (2024)
NNK, formally known as 4-(methyl nitrosamine)-1-(3-pyridyl)-1-butanoe, is a potent chemical carcinogen prevalent in cigarette smoke and is a key contributor to the development of human lung adenocarcinomas. On the other hand, autophagy plays a comple
Externí odkaz:
https://doaj.org/article/3bb11761066d46debba545ae147eee7d
Autor:
Yufei Liu, Shusen Fang, Tianshu Lin, Wei Chen, Yushan Chen, Ye Wang, Xietian Xiao, Hengfa Zheng, Lulu Liu, Jiayu Zhou, Yan Jiang, Qiuhan Hua, Yiguo Jiang
Publikováno v:
Environment International, Vol 190, Iss , Pp 108829- (2024)
Exposure to environmental carcinogens is a significant contributor to cancer development, with genetic and epigenetic alterations playing pivotal roles in the carcinogenic process. However, the interplay between epigenetic regulation and genetic chan
Externí odkaz:
https://doaj.org/article/1138450291cd44e6aeba8ae9a81b1e60
Publikováno v:
IEEE Open Journal of Signal Processing, Vol 5, Pp 1023-1030 (2024)
Spatiotemporal graph convolutional networks (STGCNs) have emerged as a desirable model for skeleton-based human action recognition. Despite achieving state-of-the-art performance, there is a limited understanding of the representations learned by the
Externí odkaz:
https://doaj.org/article/3e347ca2d72541428230d4ee19b8bfa1
Autor:
Naglaa A. Ali, Ghada H. Elsayed, Safaa H. Mohamed, Asmaa S. Abd Elkarim, Mohamed S. Aly, Abdelbaset M. Elgamal, Wael M. Elsayed, Samah A. El-Newary
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1129 (2024)
In 2022, 2.5 million cases of lung cancer were diagnosed, resulting in 1.8 million deaths. These statistics have motivated us to introduce a new natural product which is feasible in lung cancer therapies. This comprehensive study was performed to stu
Externí odkaz:
https://doaj.org/article/fd2a68a2f9c34c9590265452cf52907a
Akademický článek
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Autor:
Xin Chen, Weifan Zhang, Rujuan Liu, Zeen Zhu, Mengyuan Gong, Qiqi Wang, Weikun Qian, Zheng Wu, Qingyong Ma, Zheng Wang
Publikováno v:
Molecular Oncology, Vol 16, Iss 15, Pp 2881-2895 (2022)
Low responsiveness to chemotherapy is an important cause of poor prognosis in pancreatic cancer. Smoking is a high‐risk factor for pancreatic cancer and cancer resistance to gemcitabine; however, the underlying mechanisms remain unclear. 4‐(methy
Externí odkaz:
https://doaj.org/article/4c3d860cf00342f29345ec629a847bdf
Autor:
Sotirios G. Doukas, Dimitra P. Vageli, Panagiotis G. Doukas, Dragana Nikitovic, Aristidis Tsatsakis, Benjamin L. Judson
Publikováno v:
Current Oncology, Vol 29, Iss 8, Pp 5531-5549 (2022)
Deregulation of the DNA mismatch repair (MMR) mechanism has been linked to poor prognosis of upper aerodigestive tract cancers. Our recent in vitro data have provided evidence of crosstalk between deregulated miRNAs and MMR genes, caused by tobacco s
Externí odkaz:
https://doaj.org/article/20c7993c319d4f799cd94fa10e7fd001
Autor:
Zahra Abrishami Kia, Seyede Tayebeh Sadati Bizaki, Elham Asaádi Ghareh Tapeh, Shadmehr Mirdar Harijani, Roya Gorji Baziary
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 1261-1267 (2022)
Background: Smart and flexible methods are attracting remarkable interest in cancer-related biological and chemical therapies. To achieve a safer, affordable, and more effective cancer treatment, we evaluated the application of submaximal swimming an
Externí odkaz:
https://doaj.org/article/fab3778434a14d148dfbaa72cc9a033a
Autor:
Zahra Abrishami Kia, Seyede Tayebeh Sadati Bizaki, Elham Asaádi Ghareh Tapeh, Shadmehr Mirdar Harijani, Nayyereh Katal, Roya Gorji Baziary
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 1452-1460 (2022)
Background: Carcinogen nitrosamine 4-(methyl-trosamino)−1-(3-pyridyl)−1-butanone (NNK) remarkably affects the actions of growth factors: EGFR, VEGFR-2, as well as the natural tumor suppressors: TGFβ-1 and TIMP-1. We propose that utilizing non-ch
Externí odkaz:
https://doaj.org/article/dc4274c1edc649d7b18c944761436289
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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