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Akademický článek

Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes

Autor: Brian Cox, Thomas Kislinger, Dennis A Wigle, Anitha Kannan, Kevin Brown, Tadashi Okubo, Brigid Hogan, Igor Jurisica, Brendan Frey, Janet Rossant, Andrew Emili

Publikováno v: Molecular Systems Biology, Vol 3, Iss 1, Pp 1-15 (2007)

Abstract Although microarray analysis has provided information regarding the dynamics of gene expression during development of the mouse lung, no extensive correlations have been made to the levels of corresponding protein products. Here, we present

Externí odkaz: https://doaj.org/article/71b8f49552974b8eab2852ab94ae114a

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MIAT Is an Upstream Regulator of NMYC and the Disruption of the MIAT/NMYC Axis Induces Cell Death in

Autor: Barbara, Feriancikova, Tereza, Feglarova, Lenka, Krskova, Tomas, Eckschlager, Ales, Vicha, Jan, Hrabeta

Publikováno v: International Journal of Molecular Sciences

Neuroblastoma (NBL) is the most common extracranial childhood malignant tumor and represents a major cause of cancer-related deaths in infants. NMYC amplification or overexpression is associated with the malignant behavior of NBL tumors. In the prese

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dc3e9e2f8b36adc1f6740ed383a3f5a3
https://pubmed.ncbi.nlm.nih.gov/33806217

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Perspective on Similarities and Possible Overlaps of Congenital Disease Formation-Exemplified on a Case of Congenital Diaphragmatic Hernia and Neuroblastoma in a Neonate

Autor: Nicolas von der Weid, Stephanie J. Gros, Remo Bilang, Zihe Huo, Benedikt Brantner, Stefan Holland-Cunz

Publikováno v: Children, Vol 8, Iss 163, p 163 (2021)
Children
Volume 8
Issue 2

The coincidence of two rare diseases such as congenital diaphragmatic hernia (CDH) and neuroblastoma is exceptional. With an incidence of around 2–3:10,000 and 1:8000 for either disease occurring on its own, the chance of simultaneous presentation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f7d3908c005fb91680b2b75a501ff9
https://pubmed.ncbi.nlm.nih.gov/33671521

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AQP1-Driven Migration Is Independent of Other Known Adverse Factors but Requires a Hypoxic Undifferentiated Cell Profile in Neuroblastoma

Autor: Nicola Pini, Urs Kym, Stephanie J. Gros, Stefan Holland-Cunz, Zihe Huo

Publikováno v: Children
Volume 8
Issue 1
Children, Vol 8, Iss 48, p 48 (2021)

Neuroblastoma is a biologically very heterogeneous tumor with its clinical manifestation ranging from spontaneous regression to highly aggressive metastatic disease. Several adverse factors have been linked to oncogenesis, tumor progression and metas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db37a2af3171a3f2ac8e5c7233a75a2

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Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Subpopulation with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition

Autor: Schulte am Esch, Jan, Windmöller, Beatrice Ariane, Hanewinkel, Johannes, Storm, Jonathan, Förster, Christine, Wilkens, Ludwig, Krüger, Martin, Kaltschmidt, Barbara, Kaltschmidt, Christian

Publikováno v: Cancers
Volume 12
Issue 9
Cancers, Vol 12, Iss 2582, p 2582 (2020)

Cancer stem cells (CSC) are crucial mediators of cancer relapse. Here, we isolated two primary human colorectal cancer cell lines derived from a rectal neuroendocrine carcinoma (BKZ-2) and a colorectal adenocarcinoma (BKZ-3), both containing subpopul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ebf070b688b27b0d0192da9526b6d69b

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Akademický článek

ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma.

Autor: Tony eHuynh, Murray D Norris, Michelle eHaber, Michelle J Henderson

Publikováno v: Frontiers in Oncology, Vol 2 (2012)

Resistance to cytotoxic drugs is thought to be a major cause of treatment failure in childhood neuroblastoma, and members of the ATP-binding cassette (ABC) transporter superfamily may contribute to this phenomenon by active efflux of chemotherapeutic

Externí odkaz: https://doaj.org/article/01929d6205c04edf910e51fc7eddb973

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Akademický článek

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Dissertation/ Thesis

Mapping the Expression of Cyclin Dependent Kinase Inhibitors in High-Risk Neuroblastoma Cell Lines : Dynamics on Cell-Fate Decisions on Proliferation/Cell Cycle Arrest

Autor: López Lorenzo, Ximena

Poor prognosis for high-risk neuroblastoma patients makes it necessary to find novel treatmentstrategies. This work aims to understand the cell cycle behavior of various high-riskneuroblastoma cell lines following chemotherapy treatment. Here, we map

Externí odkaz: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-278705

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