Zobrazeno 1 - 10
of 76 730
pro vyhledávání: '"NMR-spectroscopy"'
Autor:
Michelangelo Marasco, John Kirkpatrick, Teresa Carlomagno, Jochen S. Hub, Massimiliano Anselmi
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1169-1180 (2024)
SHP2 is a tyrosine phosphatase that plays a regulatory role in multiple intracellular signaling cascades and is known to be oncogenic in certain contexts. In the absence of effectors, SHP2 adopts an autoinhibited conformation with its N-SH2 domain bl
Externí odkaz:
https://doaj.org/article/0029acf72ec94573abd1f3e2e607cb5f
Publikováno v:
Polysaccharides, Vol 5, Iss 2, Pp 142-157 (2024)
Polysaccharide-based nanoformulations with tailored hydrophobic properties have become a frontier in nanomedicine applications. Herein, highly hydrophobicized hydroxyethyl starch (HES) conjugates were synthesized by grafting stearic acid (SA) with HE
Externí odkaz:
https://doaj.org/article/137392c17e6c414f951dd8bc770d3ccf
Publikováno v:
Journal of Analytical Science and Technology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Fatty acid synthesis (FAS) is essential for the production of biological components such as cell membrane building blocks and metabolism-related compounds. There are two types of bacterial FAS: de novo FAS and FAS through the incorporation o
Externí odkaz:
https://doaj.org/article/b7be0162382b4b23a1b73ac9cc4f44fb
Autor:
Sara Vicente-Muñoz, James C. Davis, Adam Lane, Andrew N. Lane, Susan E. Waltz, Susanne I. Wells
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Recurrent and metastatic breast cancer is frequently treatment resistant. A wealth of evidence suggests that reprogrammed lipid metabolism supports cancer recurrence. Overexpression of the RON and DEK oncoproteins in breast cancer is associated with
Externí odkaz:
https://doaj.org/article/d9b37c429677417cb3d8ab66300a2177
Autor:
Fanny Kozak, Dörte Brandis, Christopher Pötzl, Ludovica M. Epasto, Daniela Reichinger, Dominik Obrist, Herwig Peterlik, Anton Polyansky, Bojan Zagrovic, Fabian Daus, Armin Geyer, Christian FW Becker, Dennis Kurzbach
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Deciphering nature's remarkable way of encoding functions in its biominerals holds the potential to enable the rational development of nature‐inspired materials with tailored properties. However, the complex processes that convert solution
Externí odkaz:
https://doaj.org/article/0b957a1634a14f3ba896d38e883105fc
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Pure shift NMR spectroscopy enables the robust probing on molecular structure and dynamics, benefiting from great resolution enhancements. Despite extensive application landscapes in various branches of chemistry, the long experimental times
Externí odkaz:
https://doaj.org/article/e89c00fe14f14d6d86a68348d4d47a79
Publikováno v:
eLife, Vol 13 (2024)
The proteasome controls levels of most cellular proteins, and its activity is regulated under stress, quiescence, and inflammation. However, factors determining the proteasomal degradation rate remain poorly understood. Proteasome substrates are conj
Externí odkaz:
https://doaj.org/article/7e37d30389dd4893a903b5e53111d161
Autor:
Roman P. Terekhov, Anastasiya D. Savina, Denis I. Pankov, Maria D. Korochkina, Amir Taldaev, Liubov M. Yakubovich, Sergey P. Zavadskiy, Anastasiya K. Zhevlakova, Irina A. Selivanova
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Dihydroquercetin (DHQ) is a representative of flavonoids that is available on the market as a food supplement and registered as an active pharmaceutical ingredient. The structure of this compound is characterized by the presence of two chiral centers
Externí odkaz:
https://doaj.org/article/1018de7c81ce4c82bc36889ad00246ed