Activity-State Dependent Reversal of Ketamine-Induced Resting State EEG Effects by Clozapine and Naltrexone in the Freely Moving Rat

Autor: Christien Bowman, Ulrike Richter, Christopher R. Jones, Claus Agerskov, Kjartan Frisch Herrik

Publikováno v: Frontiers in Psychiatry, Vol 13 (2022)

Ketamine is a non-competitive N-Methyl-D-aspartate receptor (NMDAR) antagonist used in the clinic to initiate and maintain anaesthesia; it induces dissociative states and has emerged as a breakthrough therapy for major depressive disorder. Using loca

Externí odkaz: https://doaj.org/article/892efa103c7c4d518d41b4ed0878fccc

NMDAR Neurotransmission Needed for Persistent Neuronal Firing: Potential Roles in Mental Disorders

Autor: Shengtao Yang, Hyojung Seo, Min Wang, Amy F. T. Arnsten

Publikováno v: Frontiers in Psychiatry, Vol 12 (2021)

The dorsolateral prefrontal cortex (dlPFC) generates the mental representations that are the foundation of abstract thought, and provides top-down regulation of emotion through projections to the medial PFC and cingulate cortices. Physiological recor

Externí odkaz: https://doaj.org/article/d99832f79e4443afbadb9525d9405b75

Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington’s Disease?

Autor: Kristine K. Freude, Luisana Villegas, Frederik Vilhardt, Anne Nørremølle

Publikováno v: Frontiers in Aging Neuroscience
Villegas, L, Nørremølle, A, Freude, K & Vilhardt, F 2021, ' Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington’s Disease? ', Frontiers in Aging Neuroscience, vol. 13, 736734 . https://doi.org/10.3389/fnagi.2021.736734
Frontiers in Aging Neuroscience, Vol 13 (2021)

Huntington’s disease (HD) is an inherited neurodegenerative disorder characterized by neuronal loss and tissue atrophy mainly in the striatum and cortex. In the early stages of the disease, impairment of neuronal function, synaptic dysfunction and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f3dad8144086209df9489b50758aa8
http://europepmc.org/articles/PMC8602359

Transient Enhanced GluA2 Expression in Young Hippocampal Neurons of a Fragile X Mouse Model

Autor: Andres Barria, Tue G Banke

Publikováno v: Frontiers in Synaptic Neuroscience
Frontiers in Synaptic Neuroscience, Vol 12 (2020)

AMPA-type glutamate receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits and play important roles in synaptic transmission and plasticity. Here, we have investigated the development of AMPAR-mediated syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8793ee9cec5ce98a3a114cce284110bf
http://europepmc.org/articles/PMC7745073

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