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pro vyhledávání: '"NLSDM, neutral lipid storage disease with myopathy"'
Autor:
Schrammel, Astrid, Mussbacher, Marion, Wölkart, Gerald, Stessel, Heike, Pail, Karoline, Winkler, Sarah, Schweiger, Martina, Haemmerle, Guenter, Al Zoughbi, Wael, Höfler, Gerald, Lametschwandtner, Alois, Zechner, Rudolf, Mayer, Bernd
Publikováno v:
Biochimica et Biophysica Acta
Systemic knockout of adipose triglyceride lipase (ATGL), the pivotal enzyme of triglyceride lipolysis, results in a murine phenotype that is characterized by progredient cardiac steatosis and severe heart failure. Since cardiac and vascular dysfuncti