Zobrazeno 1 - 10
of 508
pro vyhledávání: '"NLRP6"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Inflammasomes are sensors that detect cytosolic microbial molecules or cellular damage, and in response they initiate a form of lytic regulated cell death called pyroptosis. Inflammasomes signal via homotypic protein-protein interactions where CARD o
Externí odkaz:
https://doaj.org/article/50addd806ebb40ffb4662ec5c2be0c09
Autor:
Laxman Ghimire, Sagar Paudel, John Le, Liliang Jin, Shanshan Cai, Dinesh Bhattarai, Samithamby Jeyaseelan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSepsis remains a major cause of death in Intensive Care Units. Sepsis is a life-threatening multi-organ dysfunction caused by a dysregulated systemic inflammatory response. Pattern recognition receptors, such as TLRs and NLRs contribute t
Externí odkaz:
https://doaj.org/article/f0e2f60eaf86464bbcf7aca8b6046c69
Autor:
Lanqing Sun, Kai Huang, Qifeng Deng, Yuan Zhu, Yu Cao, Kedi Dong, Sidi Yang, Yuanyuan Li, Shuyan Wu, Rui Huang
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e28432- (2024)
Non-typhoidal Salmonella infection is among the most frequent foodborne diseases threatening human health worldwide. The host circadian clock orchestrates daily rhythms to adapt to environmental changes, including coordinating immune function in resp
Externí odkaz:
https://doaj.org/article/ba567c04c51f4ae0a42ba2231f4a07dc
Publikováno v:
Neurobiology of Disease, Vol 192, Iss , Pp 106434- (2024)
Innate inflammation is crucial for ischemic stroke development. NLRP6, a nucleotide-binding and oligomerization domain-like receptors (NLRs) family member, regulates innate inflammation. Whether NLRP6 regulates neurological damage and neuroinflammati
Externí odkaz:
https://doaj.org/article/afb42a9212974584aff5fe96c2930bb2
Autor:
Mégane Nascimento, Sarah Huot-Marchand, Manoussa Fanny, Marjolène Straube, Marc Le Bert, Florence Savigny, Lionel Apetoh, Jacques Van Snick, Fabrice Trovero, Mathias Chamaillard, Valérie F. J. Quesniaux, Bernhard Ryffel, Philippe Gosset, Aurélie Gombault, Nicolas Riteau, Harry Sokol, Isabelle Couillin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chronic obstructive pulmonary disease (COPD) is a major health issue primarily caused by cigarette smoke (CS) and characterized by breathlessness and repeated airway inflammation. NLRP6 is a cytosolic innate receptor controlling intestinal inflammati
Externí odkaz:
https://doaj.org/article/a7d159a73b8e40fbaeb58a9775e4aac6
Autor:
Chuanfeng Tang, Qiaona Wang, Jingyan Shen, Congying Wang, Hong Ding, Shiyu Wen, Fan Yang, Ruiqing Jiao, Xingxin Wu, Jianmei Li, Lingdong Kong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 5, Pp 2017-2038 (2023)
Neurogenesis decline in hippocampal dentate gyrus (DG) participates in stress-induced depressive-like behaviors, but the underlying mechanism remains poorly understood. Here, we observed low-expression of NOD-like receptor family pyrin domain contain
Externí odkaz:
https://doaj.org/article/0ec31c9ba00740ee9e6f24b26d12a67b
Autor:
Xinzhe Lou, Jianru Liu, Xiangying Ouyang, Wenyi Liu, Ying Xie, Jinsheng Zhong, Peiying Lv, Shengnan Zhang
Publikováno v:
Journal of Dental Sciences, Vol 18, Iss 2, Pp 510-516 (2023)
Background/purpose: Porphyromonas gingivalis (P. gingivalis) could induce the activation of vascular endothelial cells and promote the formation of atherosclerosis. Nucleotide-binding oligomerization domain-like receptor family pyrin domain containin
Externí odkaz:
https://doaj.org/article/6fbf6cc909464554a42fb7d553c93a70
Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 808-823 (2023)
Abstract Background Pyroptosis is a unique inflammatory‐related cell death process, and inflammation is considered to be a key factor in hepatocellular carcinoma (HCC). However, the pyroptosis landscape in HCC has not been thoroughly studied. Metho
Externí odkaz:
https://doaj.org/article/500919a209784fd5848b54eaf3f2c303
Autor:
Xingping Wu, Zheng Zeng, Hongliang Tian, Lianci Peng, Dongyi Xu, Yu Wang, Chao Ye, Yuanyi Peng, Rendong Fang
Publikováno v:
Veterinary Research, Vol 53, Iss 1, Pp 1-12 (2022)
Abstract Pasteurella multocida (P. multocida) can cause severe respiratory disease in cattle, resulting in high mortality and morbidity. Inflammasomes are multiprotein complexes in the cytoplasm that recognize pathogens and play an important role in
Externí odkaz:
https://doaj.org/article/64b6c711e8e04ad3b75c7071065b39f2
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