Zobrazeno 1 - 10
of 246
pro vyhledávání: '"NLRP3-inflammasome"'
Autor:
Ana T. A. Sachetto, Nigel Mackman
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/02041e3081e648e7a7be3dc09dbf4846
Autor:
A. V. Lugovaya, N. M. Kalinina, A. M. Ivanov, Yu. V. Nikitin, I. А. Sukhina, V. F. Mitreikin, E. V. Semenova
Publikováno v:
Медицинская иммунология, Vol 25, Iss 4, Pp 939-946 (2023)
The postischemic inflammatory response plays a significant role in the pathogenesis of acute ischemic stroke (IS). It has been established that acute IS is accompanied by aseptic inflammation, which induces the activation of costimulatory molecules i
Externí odkaz:
https://doaj.org/article/2b9a1fda622a4d82a359d20cc46d8bf7
Autor:
Audrey Cambon, Charlotte Rebelle, Richard Bachelier, Laurent Arnaud, Stéphane Robert, Marie Lagarde, Romain Muller, Edwige Tellier, Yéter Kara, Aurélie Leroyer, Catherine Farnarier, Loris Vallier, Corinne Chareyre, Karine Retornaz, Anne-Laure Jurquet, Tu-Anh Tran, Romaric Lacroix, Françoise Dignat-George, Gilles Kaplanski
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveIL-1β is a leaderless cytokine with poorly known secretory mechanisms that is barely detectable in serum of patients, including those with an IL-1β-mediated disease such as systemic juvenile idiopathic arthritis (sJIA). Leukocyte microvesi
Externí odkaz:
https://doaj.org/article/ff2d2c95d2b743a68a3fa2aad6e86172
Autor:
Siming Huo, Xuliang Zhang, Jinyu Xu, Jian Zhang, Jiayu Du, Bo Li, Miao Song, Bing Shao, Yanfei Li, Feibo Xu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 264, Iss , Pp 115459- (2023)
Aluminum is a neurotoxic food contaminant. Aluminum trichloride (AlCl3) causes hippocampal mitochondrial damage, leading to hippocampal injury. Damaged mitochondria can release mitochondrial reactive oxygen species (mtROS) and activate nucleotide-bin
Externí odkaz:
https://doaj.org/article/106673d1164647a6ac4933aa4ead029e
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 15, Pp 2479-2488 (2022)
Yan Pan, Lei Liu, Huijuan Yang, Weidong Chen, Zheng Chen, Jing Xu Department of Nephrology, First Affiliated Hospital of Bengbu Medical College, Bengbu City, People’s Republic of ChinaCorrespondence: Yan Pan, Department of Nephrology, First Affilia
Externí odkaz:
https://doaj.org/article/d8842d803cb644f5a0064476c8a5fae7
Autor:
Joseph W. Guarnieri, Alessia Angelin, Deborah G. Murdock, Patrick Schaefer, Prasanth Portluri, Timothy Lie, Jessica Huang, Douglas C. Wallace
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCompared to healthy controls, severe COVID19 patients display increased levels of activated NLRP3-inflammasome (NLRP3-I) and interleukin (IL)-1β. SARS-CoV-2 encodes viroporin proteins E and Orf3a(2-E+2-3a) with homologs to SARS-CoV-1, 1-E+
Externí odkaz:
https://doaj.org/article/a72620b0a8fe4e418e304ad3947267a0
Akademický článek
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Autor:
Yuanyuan Du, Linyu Chen, Huimin Qiao, Lan Zhang, Lan Yang, Peipei Zhang, Jing Wang, Cong Zhang, Wei Jiang, Renhao Xu, Xiangjian Zhang
Publikováno v:
Brain Sciences, Vol 13, Iss 6, p 939 (2023)
Background: Our previous research revealed that inflammation plays an important role in the pathophysiology of cerebral ischemia. The function of the NOD-like receptor protein 3 (NLRP3) inflammasome is to activate the inflammatory process. Recent fin
Externí odkaz:
https://doaj.org/article/24577bef40e24e05a7d9329324e2f018
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 7, Pp n/a-n/a (2022)
Abstract Mitochondria‐associated endoplasmic reticulum membranes (MAM) are specialized subcellular compartments that are shaped by endoplasmic reticulum (ER) subdomains placed side by side to the outer membrane of mitochondria (OMM) being connected
Externí odkaz:
https://doaj.org/article/cc8b929609774120866530f465e5e59e
Autor:
Mohamed S. Attia, Heba A. Ewida, Mohamed Aly Abdel Hafez, Shohda A. El-Maraghy, Maha M. El-Sawalhi
Publikováno v:
Diagnostics, Vol 13, Iss 8, p 1448 (2023)
Relapsing–remitting multiple sclerosis (RRMS) is the most prevalent MS subtype. Ample evidence has indicated that long noncoding RNAs (lncRNAs) are crucial players in autoimmune and inflammatory disorders. This study investigated the expression of
Externí odkaz:
https://doaj.org/article/7c8dd0547a3340d28a583375fbe1efa9