Zobrazeno 1 - 10
of 26
pro vyhledávání: '"NLRP3, NLR family pyrin domain containing 3"'
Autor:
Zeinab Amini-Farsani, Mahtab Yadollahi-Farsani, Samira Asgharzade, Fatemeh Forouzanfar, Mitra Yadollahi, Samaneh Arab
Publikováno v:
International Immunopharmacology
COVID-19 is the cause of a pandemic associated with substantial morbidity and mortality. As yet, there is no available approved drug to eradicate the virus. In this review article, we present an alternative study area that may contribute to the devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8773adb656d31880c2095312d49df64
http://europepmc.org/articles/PMC8378592
http://europepmc.org/articles/PMC8378592
Publikováno v:
JAAD Case Reports
JAAD Case Reports, Vol 6, Iss 6, Pp 543-545 (2020)
JAAD Case Reports, Vol 6, Iss 6, Pp 543-545 (2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb65fe236ad88d9d73540c5196783af
https://doi.org/10.1016/j.jdcr.2020.03.012
https://doi.org/10.1016/j.jdcr.2020.03.012
Autor:
Yusuke Ito, Yasuhiro Maejima, Shun Nakagama, Yuka Shiheido-Watanabe, Natsuko Tamura, Tetsuo Sasano
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • An appropriate dose of RIV to inhibit the activity of factor Xa significantly suppressed the atherosclerotic area in the aorta of HFD-fed ApoE–/– mice. • Macrophage autophagy induced by 7KC administration was
Highlights • An appropriate dose of RIV to inhibit the activity of factor Xa significantly suppressed the atherosclerotic area in the aorta of HFD-fed ApoE–/– mice. • Macrophage autophagy induced by 7KC administration was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0e5e26a6fa69436ef8f97344ae5b05
https://pubmed.ncbi.nlm.nih.gov/35024502
https://pubmed.ncbi.nlm.nih.gov/35024502
Autor:
Vera Maria Morsch, Karine Paula Reichert, Milagros Fanny Vera Castro, Naiara Stefanello, Vanessa Valéria Miron, Andréia Machado Cardoso, Maria Rosa Chitolina Schetinger, Charles Elias Assmann, Nathieli B. Bottari
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss, Pp 111273-(2021)
Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy
Graphical abstract
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34db00a41121e428fb7b9d4795d39e99
http://www.sciencedirect.com/science/article/pii/S0753332221000585
http://www.sciencedirect.com/science/article/pii/S0753332221000585
Autor:
E. Romano, Alessandra Gennari, Alessio Cortellini, David J. Pinato, G. Pentheroudakis, Meera Patel, Gino M Dettorre
Publikováno v:
ESMO Open
Inflammation is an established driver of severe SARS-CoV-2 infection and a mechanism linked to the increased susceptibility to fatal COVID-19 demonstrated by patients with cancer. As patients with cancer exhibit a higher level of inflammation compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acc3719139de40efdf357110cb4e77d
http://hdl.handle.net/10044/1/87455
http://hdl.handle.net/10044/1/87455
Autor:
Chevalier, Christophe, Leymarie, Olivier, Sedano, Laura, Da Costa, Bruno, Richard, Charles-Adrien, Maisonnasse, Pauline, Réfregiers, Matthieu, Jamme, Frédéric, Le Goffic, Ronan
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297 (1), ⟨10.1016/j.jbc.2021.100885⟩
The Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297 (1), ⟨10.1016/j.jbc.2021.100885⟩
The Journal of Biological Chemistry
International audience; PB1-F2 is a virulence factor of influenza A virus known to increase viral pathogenicity in mammalian hosts. PB1-F2 is an intrinsically disordered protein displaying a propensity to form amyloid-like fibers. However, the correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::95ca4df1633cfcb61d49c9e8e0cfa491
https://hal.archives-ouvertes.fr/hal-03299147/document
https://hal.archives-ouvertes.fr/hal-03299147/document
Publikováno v:
Seminars in Cell & Developmental Biology
Receptor Interacting Protein Kinases (RIPKs) are cellular signaling molecules that are critical for homeostatic signaling in both communicable and non-communicable disease processes. In particular, RIPK1, RIPK2, RIPK3 and RIPK7 have emerged as key me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628bb448c2d6de5b9d7755cdadd35794
http://europepmc.org/articles/PMC7448748
http://europepmc.org/articles/PMC7448748
Publikováno v:
Pharmacological Research
Graphical abstract Molecular targets modulated by artemisinins in respiratory diseases.
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184b9b3d7b7767e97cb84ac3227c7da4
Publikováno v:
Pharmacological Research
Graphical abstract
Glucocorticosteroids are the first-line therapy for controlling airway inflammation in asthma. They bind intracellular glucocorticoid receptors to trigger increased expression of anti-inflammatory genes and suppression of pro-
Glucocorticosteroids are the first-line therapy for controlling airway inflammation in asthma. They bind intracellular glucocorticoid receptors to trigger increased expression of anti-inflammatory genes and suppression of pro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e5d0a8b671ed51b0c55d2a089cbbec
Autor:
Lu, Ping-Hsun, Tseng, Chien-Wei, Lee, Jing-Ling, Lee, En-Yu, Lin, Yu-Ping, Lin, I-Hsin, Yu, Min-Chien, Lu, Kuo-Cheng, Kuo, Ko-Lin
Publikováno v:
Pharmacological Research-Modern Chinese Medicine
Background : SARS-CoV-2 has led to a sharp increase in the number of hospitalizations and deaths from pneumonia and multiorgan disease worldwide; therefore, SARS-CoV-2 has become a global health problem. Supportive therapies remain the mainstay treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2244e4d95e5172a8359236fa899ba577
https://doi.org/10.1016/j.prmcm.2021.100024
https://doi.org/10.1016/j.prmcm.2021.100024