Zobrazeno 1 - 10
of 77
pro vyhledávání: '"NLRP10"'
Autor:
Qiuju Liang, Jiajun Jing, Huiming He, Xiaofeng Huang, Jianing Liu, Mingjun Wang, Zijuan Qi, Li'e Zhang, Ziang Huang, Yuanliang Yan, Sijin Liu, Ming Gao, Yunfeng Zou
Publikováno v:
Environment International, Vol 187, Iss , Pp 108672- (2024)
Manganese (Mn) is an essential micronutrient required for various biological processes but excess exposure to Mn can cause neurotoxicity. However, there are few reports regarding the toxicity effect of Mn on the kidney as well as the underlying molec
Externí odkaz:
https://doaj.org/article/1b0eb4fd0b2243f5ab43c39c43de013b
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Akademický článek
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Autor:
Tomasz Próchnicki, Matilde B. Vasconcelos, Kim S. Robinson, Matthew S. J. Mangan, Dennis De Graaf, Kateryna Shkarina, Marta Lovotti, Lena Standke, Romina Kaiser, Rainer Stahl, Fraser G. Duthie, Maximilian Rothe, Kateryna Antonova, Lea-Marie Jenster, Zhi Heng Lau, Sarah Rösing, Nora Mirza, Clarissa Gottschild, Dagmar Wachten, Claudia Günther, Thomas A. Kufer, Florian I. Schmidt, Franklin L. Zhong, Eicke Latz
Publikováno v:
Nature immunology 24(4), 595-603 (2023). doi:10.1038/s41590-023-01451-y
Upon detecting pathogens or cell stress, several NOD-like receptors (NLRs) form inflammasome complexes with the adapter ASC and caspase-1, inducing gasdermin D (GSDMD)-dependent cell death and maturation and release of IL-1β and IL-18. The triggers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951cef744dde927be85ce561d1cb4398
NOD2 and reproduction-associated NOD-like receptors have been lost during the evolution of pangolins
Publikováno v:
Immunogenetics
NOD-like receptors (NLRs) are sensors of pathogen-associated molecular patterns with critical roles in the control of immune responses and programmed cell death. Recent studies have revealed inter-species differences in mammalian innate immune genes
Autor:
Krishnaswamy, Jayendra Kumar, Singh, Arpita, Gowthaman, Uthaman, Wu, Renee, Gorrepati, Pavane, Nascimento, Manuela Sales, Gallman, Antonia, Liu, Dong, Rhebergen, Anne Marie, Calabro, Samuele, Xu, Lan, Ranney, Patricia, Srivastava, Anuj, Ranson, Matthew, Gorham, James D., McCaw, Zachary, Kleeberger, Steven R., Heinz, Leonhard X., Müller, André C., Bennett, Keiryn L., Superti-Furga, Giulio, Henao-Mejia, Jorge, Sutterwala, Fayyaz S., Williams, Adam, Flavell, Richard A., Eisenbarth, Stephanie C.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Mar 01. 112(10), 3056-3061.
Externí odkaz:
https://www.jstor.org/stable/26461765
Akademický článek
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Autor:
Maurizio Vacca, Julia Böhme, Lia Paola Zambetti, Hanif Javanmard Khameneh, Bhairav S. Paleja, Federica Laudisi, Adrian W. S. Ho, Kurt Neo, Keith Weng Kit Leong, Mardiana Marzuki, Bernett Lee, Michael Poidinger, Laura Santambrogio, Liana Tsenova, Francesca Zolezzi, Gennaro De Libero, Amit Singhal, Alessandra Mortellaro
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
NLRP10 is a nucleotide-binding oligomerization domain-like receptor that functions as an intracellular pattern recognition receptor for microbial products. Here, we generated a Nlrp10−/− mouse to delineate the role of NLRP10 in the host immune re
Externí odkaz:
https://doaj.org/article/0d658a4472974b4ead4b0eed71d2a1e9
Publikováno v:
The Journal of Immunology. 202:218-227
NOD-like receptors (NLR) are critical regulators of innate immune signaling. The NLR family consists of 22 human proteins with a conserved structure containing a central oligomerization NACHT domain, an N-terminal interaction domain, and a variable n
Publikováno v:
Toxicology. :52-67
Chronic obstructive pulmonary disease (COPD) is a progressive, life-threatening disease that causes irreversible lung damage. Cigarette smoking is the chief etiologic factor for the commencement of this condition. Despite constant efforts to develop