Zobrazeno 1 - 10
of 636
pro vyhledávání: '"NLRC5"'
Autor:
Bao Guo, Haiqing Zhu, Chengwei Xiao, Jing Zhang, Xiaojing Liu, Yuan Fang, Bing Wei, Junhui Zhang, Yunxia Cao, Lei Zhan
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Endometriosis is well known as a chronic inflammatory disease. The development of endometriosis is heavily influenced by the estrogen receptor β (ERβ), while NOD-like receptors (NLRs) family CARD domain-containing 5 (NLRC5) exhi
Externí odkaz:
https://doaj.org/article/4315ad9eeb164d10904aecf13aeb18ac
Autor:
Lin Ling, Jiahua Chen, Lei Zhan, Juanjuan Fu, Runhua He, Wenyan Wang, Bing Wei, Xiaofeng Ma, Yunxia Cao
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cervical cancer (CC) is the fourth most common cancer among women worldwide. NLR Family CARD Domain Containing 5 (NLRC5) plays an important role in tumorigenesis. However, its effect and mechanism in CC remains unclear. In this study, we aim
Externí odkaz:
https://doaj.org/article/aac4fde8862347acbd4cda4b6bf87677
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
NLRC5, the largest member of the nucleotide-binding and oligomerization domain (NOD)-like receptor (NLR) family, has been reported to participate in the regulation of immune function and is associated with chronic inflammatory diseases. However, the
Externí odkaz:
https://doaj.org/article/dc123e715b1e402fa2af42faaecfd8d5
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Background Temporomandibular joint osteoarthritis (TMJOA) is a degenerative cartilage disease. 17β‐estradiol (E2) aggravates the pathological process of TMJOA; however, the mechanisms of its action have not been elucidated. Thus, we inves
Externí odkaz:
https://doaj.org/article/f9304a770e4145e5aa15cddc9b274321
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The nucleotide-binding and oligomerization domain-like receptors (NLRs) NLR family CARD domain-containing protein 5 (NLRC5) and Class II Major Histocompatibility Complex Transactivator (CIITA) are transcriptional regulators of major histocompatibilit
Externí odkaz:
https://doaj.org/article/927c3d47eb6a418fa84e079df55b3301
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-13 (2024)
Abstract Background Endothelial-to-Mesenchymal Transformation (EndMT) plays key roles in endothelial dysfunction during the pathological progression of atherosclerosis; however, its detailed mechanism remains unclear. Herein, we explored the biologic
Externí odkaz:
https://doaj.org/article/a640c9e826a84eb8a1c678610505ec24
Publikováno v:
Universa Medicina, Vol 43, Iss 2 (2024)
Background Gastrointestinal (GI) cancer is affecting millions of people globally, leading to high incidence and mortality rates and a heavy economic burden. Nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) are a family of cytosol
Externí odkaz:
https://doaj.org/article/fd0d4be3157f47ab85048a09abd35e3a
Akademický článek
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Autor:
Galaxia M. Rodriguez, Edward Yakubovich, Humaira Murshed, Vincent Maranda, Kristianne J.C. Galpin, Alison Cudmore, Andrew M. R. Hanna, Elizabeth Macdonald, Shashankan Ramesh, Kenneth Garson, Barbara C. Vanderhyden
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionEpithelial ovarian cancer (OC) stands as one of the deadliest gynecologic malignancies, urgently necessitating novel therapeutic strategies. Approximately 60% of ovarian tumors exhibit reduced expression of major histocompatibility comple
Externí odkaz:
https://doaj.org/article/88f6fbac7a8c465a9fac7afe29769ae6
Autor:
Zhaolin Liu, Chenye Shen, Heng Li, Jiabin Tong, Yufei Wu, Yuanyuan Ma, Jinghui Wang, Zishan Wang, Qing Li, Xiaoshuang Zhang, Hongtian Dong, Yufang Yang, Mei Yu, Jian Wang, Renyuan Zhou, Jian Fei, Fang Huang
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Parkinson’s disease (PD) is mainly characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and neuroinflammation mediated by overactivated microglia and astrocytes. NLRC5 (nucleoti
Externí odkaz:
https://doaj.org/article/d737bffdd402413a88282475ecf69a39