Die Kämpfe únd schláchten—the struggles and battles of innate-like effector T lymphocytes with microbes

Autor: Sebastian Joyce, Gosife Donald Okoye, John P. Driver

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response. A multitudinous group of lymphoid lineage cells does not fit the con

Externí odkaz: https://doaj.org/article/8fabdf8613ed49518612798e8abc912b

Innate immunity and early liver inflammation

Autor: Yang Zhou, Jordi

The innate system constitutes a first-line defence mechanism against pathogens. 80% of the blood supply entering the human liver arrives from the splanchnic circulation through the portal vein, so it is constantly exposed to immunologically active su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5154932ab175a70e20f4173df5b3e3

Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell–Mediated Hepatitis via Compensatory Up-regulation of CXCR2–Related Chemokine Activity

Autor: Jichang Li, Meng Li, Yankai Wen, Qiang Xia, Min Xu, Yongbing Qian, Lei Xia, Lili Chen, Yihan Qian, Xiaoni Kong, Hailong Wu, Jinyang Gu, Jia-Xin Li

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 3, Pp 623-639 (2019)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Chemokine-mediated immune cell recruitment plays pivotal roles in liver inflammation. C-C motif chemokine ligand 5 (CCL5) has been shown to be responsible for the recruitment of monocytes/macrophages and has been implicated in vario

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b36c1624a6dabca934c6afbe8ea6e80
https://doi.org/10.1016/j.jcmgh.2018.12.009

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

NKT cells are important mediators of hepatic ischemia-reperfusion injury

Autor: James A, Richards, Stephen J, Wigmore, Stephen M, Anderton, Sarah E M, Howie

Publikováno v: Transplant Immunology

Introduction IRI results from the interruption then reinstatement of an organ's blood supply, and this poses a significant problem in liver transplantation and resectional surgery. In this paper, we explore the role T cells play in the pathogenesis o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1be54b928882c537fef5b63aa80fee1a
https://pubmed.ncbi.nlm.nih.gov/28797737