Zobrazeno 1 - 10
of 21
pro vyhledávání: '"NIKI MASTRODIMOU"'
Autor:
Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, Kyriaki Thermos
NADPH oxidases (NOXs) are major players in generating reactive oxygen species (ROS) and are implicated in various neurodegenerative ocular pathologies. The aim of this study was to investigate the role of a NOX4 inhibitor (GLX7013114) in two in vivo,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c35b1ca84104edf9f512c67f80fde1
https://doi.org/10.2337/figshare.22134833
https://doi.org/10.2337/figshare.22134833
Autor:
Dimitris Spyridakos, Niki Mastrodimou, Kiran Vemuri, Thanh C. Ho, Spyros P. Nikas, Alexandros Makriyannis, Kyriaki Thermos
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 240
Oxidative stress, neurodegeneration, neuroinflammation, and vascular leakage are believed to play a key role in the early stage of diabetic retinopathy (ESDR). The aim of this study was to investigate the blockade of cannabinoid receptor 1 (CB1R) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590402334a74b581d8176506012b9d3e
Autor:
Ruth Ibán-Arias, Niki Mastrodimou, Achille Gravanis, Silvia Lisa, Ioannis Charalampopoulos, Kyriaki Thermos, Smaragda Poulaki
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 257:2429-2436
Diabetic retinopathy (DR) is a complex eye disease associated with diabetes mellitus. It is characterized by three pathophysiological components, namely microangiopathy, neurodegeneration, and inflammation. We recently reported that intraperitoneal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d798c28a26a088e181074f323b8ce083
https://doi.org/10.1007/s00417-019-04460-6
https://doi.org/10.1007/s00417-019-04460-6
Autor:
Antonis Kouvarakis, Haralambos E. Katerinopoulos, Sofia Papadogkonaki, Emmanuil Koulakis, Niki Mastrodimou, Achille Gravanis, Despina Kokona, Silvia Lisa, Ruth Ibán-Arias, Panagiota Iordanidou, Aggeliki Sotiriou, Myrto Fothiadaki, Kyriaki Thermos, Ioannis Charalampopoulos
Publikováno v:
Diabetes. 67:321-333
BNN27, a C17-spiroepoxy derivative of DHEA, was shown to have antiapoptotic properties via mechanisms involving the nerve growth factor receptors (tropomyosin-related kinase A [TrkA]/neurotrophin receptor p75 [p75NTR]). In this study, we examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f77a26a9443bdd806dbf357c4bb862
https://doi.org/10.2337/db17-0391
https://doi.org/10.2337/db17-0391
Autor:
Hara Polioudaki, Sofia Papadogkonaki, Dimitris Spyridakos, Stavroula Dionysopoulou, Kyriaki Thermos, Niki Mastrodimou
Publikováno v:
Neurochemistry International. 142:104907
Cannabinoids have been shown to protect the retina from ischemic/excitotoxic insults. The aim of the present study was to investigate the neuroprotective and anti-inflammatory properties of the synthetic cannabinoid (R)-WIN55,212-2 (CB1/CB2 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b157f88b2d04796e494e610267787c9
https://doi.org/10.1016/j.neuint.2020.104907
https://doi.org/10.1016/j.neuint.2020.104907
Autor:
Elias A. Kouroumalis, George Notas, C. Xidakis, E. Renieri, Niki Mastrodimou, George Kolios, Kyriaki Thermos
Publikováno v:
Regulatory Peptides. 143:76-82
The present study investigated the presence of somatostatin receptor subtypes (ssts) and the endogenous peptides somatostatin and cortistatin in rat Kupffer cells, since modulation of these cells by somatostatin may be important for the beneficial ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b886b882b2c77ee06814d573efd2936c
https://doi.org/10.1016/j.regpep.2007.03.005
https://doi.org/10.1016/j.regpep.2007.03.005
Publikováno v:
Neuroscience Letters. 337:143-146
The neuropeptide somatostatin is found in the retina of many species, yet its role in the visual process remains to be elucidated. The aim of the present study was to examine the expression and cellular localization of somatostatin receptor subtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6679497e5cedc395e0e9298fae35ed8
https://doi.org/10.1016/s0304-3940(02)01326-5
https://doi.org/10.1016/s0304-3940(02)01326-5
Autor:
George Notas, Niki Mastrodimou, Apostolos Zaravinos, Elias A. Kouroumalis, Ourania Sfakianaki, Georgios D. Ayiomamitis, M Georgiadou, Kyriaki Thermos, Ioannis Drygiannakis
Publikováno v:
Oncoscience
Peptide hormone somatostatin and its receptors have a wide range of physiological functions and play a role in the treatment of numerous human diseases, including colorectal cancer. Octreotide, a synthetic somatostatin-analog peptide, inhibits growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07467ddde048e4c851f9b9c38bb0f348
https://pubmed.ncbi.nlm.nih.gov/26379105
https://pubmed.ncbi.nlm.nih.gov/26379105
Autor:
Ioannis Charalampopoulos, Niki Mastrodimou, Despina Kokona, Iosif Pediaditakis, Kyriaki Thermos, H.A. Schmid
Publikováno v:
Experimental eye research. 103
The neuropeptide somatostatin and selective analogs for the sst(2/5) receptor subtypes provided neuroprotection against retinal chemical ischemia ex vivo and AMPA [(RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hydrobromide] induced retin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d25fdce6ab6e4c1e85e6f8b9cf2798f
https://pubmed.ncbi.nlm.nih.gov/22960304
https://pubmed.ncbi.nlm.nih.gov/22960304
Publikováno v:
Acta Ophthalmologica. 89
Purpose The aim of the present study was to investigate the neuroprotective properties of SOM230, a new metabolically stable analogue of somatostatin, with a 12h plasma half-life and high affinity for the sst1,2,3,5 receptor subtypes. Methods Female
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cf8bb8b5ec6f6c3ead02fe46e61c684
https://doi.org/10.1111/j.1755-3768.2011.455.x
https://doi.org/10.1111/j.1755-3768.2011.455.x