Zobrazeno 1 - 10
of 24
pro vyhledávání: '"NIHR Pancreas Biomedical Research Unit"'
Autor:
Mukherjee, R., Mareninova, O. A., Odinokova, I. V., Huang, W., Murphy, J., Chvanov, M., Javed, M. A., Wen, L., Booth, D. M., Cane, M. C., Awais, M., Gavillet, B., Pruss, R. M., Schaller, S., Molkentin, J. D., Tepikin, A. V., Petersen, Ole Holger, Pandol, S. J., Gukovsky, I., Criddle, D. N., Gukovskaya, A. S., Sutton, R., Latawiec, D., Rajamanoharan, D., Mclaughlin, E., Ghaneh, P., Halloran, C., Neoptolemos, J. P., Raraty, M. G., French, S. W., NIHR Pancreas Biomedical Research Unit
Objective Acute pancreatitis is caused by toxins that induce acinar cell calcium overload, zymogen activation, cytokine release and cell death, yet is without specific drug therapy. Mitochondrial dysfunction has been implicated but the mechanism not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::de0d119fbe36aa959048cae27cf8dd1c
https://orca.cardiff.ac.uk/id/eprint/74278/1/1333.full.pdf
https://orca.cardiff.ac.uk/id/eprint/74278/1/1333.full.pdf
Autor:
Mukherjee, Rajarshi, Mareninova, Olga A, Odinokova, Irina V, Huang, Wei, Murphy, John, Chvanov, Michael, Javed, Muhammad A, Wen, Li, Booth, David M, Cane, Matthew C, Awais, Muhammad, Gavillet, Bruno, Pruss, Rebecca M, Schaller, Sophie, Molkentin, Jeffery D, Tepikin, Alexei V, Petersen, Ole H, Pandol, Stephen J, Gukovsky, Ilya, Criddle, David N, Gukovskaya, Anna S, Sutton, Robert, NIHR Pancreas Biomedical Research Unit
Publikováno v:
Gut
GUT
Gut, vol 65, iss 8
GUT
Gut, vol 65, iss 8
Objective: Acute pancreatitis is caused by toxins that induce acinar cell calcium overload, zymogen activation, cytokine release and cell death, yet is without specific drug therapy. Mitochondrial dysfunction has been implicated but the mechanism not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b807c5b3b26f4b174ba6944811d47f2c
https://pubmed.ncbi.nlm.nih.gov/30944111
https://pubmed.ncbi.nlm.nih.gov/30944111
Autor:
Alabraba E; Liverpool NIHR Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool L69 3GA, UK., Manu N; Liverpool NIHR Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool L69 3GA, UK., Fairclough G; Liverpool NIHR Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool L69 3GA, UK., Sutton R; Liverpool NIHR Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool L69 3GA, UK.
Publikováno v:
Oxford medical case reports [Oxf Med Case Reports] 2018 May 31; Vol. 2018 (5), pp. omx056. Date of Electronic Publication: 2018 May 31 (Print Publication: 2018).
Autor:
Neoptolemos JP; NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK., Halloran CM, Ghaneh P, Kleeff J
Publikováno v:
Annals of surgery [Ann Surg] 2018 Feb; Vol. 267 (2), pp. e35-e36.
Autor:
Kong B; Department of Surgery, Technische Universität München (TUM), Munich, Germany.; Department of Gastroenterology, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China., Bruns P; Department of Surgery, Technische Universität München (TUM), Munich, Germany.; Institute of Computational Biology, Helmholtz-Zentrum München GmbH, Neuherberg, Germany., Behler NA; Department of Surgery, Technische Universität München (TUM), Munich, Germany., Chang L; Department of Surgery, Technische Universität München (TUM), Munich, Germany., Schlitter AM; Institute of Pathology, TUM, Munich, Germany., Cao J; Department of Surgery, Technische Universität München (TUM), Munich, Germany., Gewies A; Institute für Klinische Chemie und Pathobiochemie, TUM, Munich, Germany.; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München, Neuherberg, Germany.; German Cancer Consortium (DKTK) at the partner site Munich and German Cancer Research Center (DKFZ), Heidelberg, Germany., Ruland J; Institute für Klinische Chemie und Pathobiochemie, TUM, Munich, Germany.; German Cancer Consortium (DKTK) at the partner site Munich and German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany., Fritzsche S; Department of Surgery, Technische Universität München (TUM), Munich, Germany., Valkovskaya N; Department of Surgery, Technische Universität München (TUM), Munich, Germany., Jian Z; Department of Surgery, Technische Universität München (TUM), Munich, Germany., Regel I; Institute of Pathology, Heinrich-Heine University, Duesseldorf, Germany., Raulefs S; Department of Surgery, Technische Universität München (TUM), Munich, Germany., Irmler M; Institute of Experimental Genetics, Helmholtz Zentrum München GmbH, Neuherberg, Germany., Beckers J; Institute of Experimental Genetics, Helmholtz Zentrum München GmbH, Neuherberg, Germany.; Chair of Experimental Genetics, Technische Universität München, Freising, Germany.; Deutsches Zentrum für Diabetesforschung, Neuherberg, Germany., Friess H; Department of Surgery, Technische Universität München (TUM), Munich, Germany., Erkan M; Department of Surgery, Koc University, Istanbul, Turkey., Mueller NS; Institute of Computational Biology, Helmholtz-Zentrum München GmbH, Neuherberg, Germany., Roth S; Department of Surgery, University of Heidelberg, Heidelberg, Germany., Hackert T; Department of Surgery, University of Heidelberg, Heidelberg, Germany., Esposito I; Institute of Pathology, Heinrich-Heine University, Duesseldorf, Germany., Theis FJ; Institute of Computational Biology, Helmholtz-Zentrum München GmbH, Neuherberg, Germany.; Department of Mathematics, TUM, Munich, Germany., Kleeff J; Department of Surgery, Technische Universität München (TUM), Munich, Germany.; NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK., Michalski CW; Department of Surgery, University of Heidelberg, Heidelberg, Germany.
Publikováno v:
Gut [Gut] 2018 Jan; Vol. 67 (1), pp. 146-156. Date of Electronic Publication: 2016 Sep 19.
Autor:
Diener MK; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany; Study Center of the German Surgical Society, University of Heidelberg, Heidelberg, Germany., Hüttner FJ; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany; Study Center of the German Surgical Society, University of Heidelberg, Heidelberg, Germany., Kieser M; Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany., Knebel P; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany., Dörr-Harim C; Study Center of the German Surgical Society, University of Heidelberg, Heidelberg, Germany., Distler M; Department of Visceral, Thoracic and Vascular Surgery, University Hospital Dresden, Technical University Dresden, Dresden, Germany., Grützmann R; Department of Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Wittel UA; Department of General and Visceral Surgery, Medical Centre, University of Freiburg, Freiburg, Germany., Schirren R; Department of Surgery, University Hospital Rechts der Isar, Technical University Munich, Munich, Germany., Hau HM; Department of Visceral, Transplantation, Thoracic, and Vascular Surgery, University Hospital Leipzig, Leipzig, Germany., Kleespies A; Department of General, Visceral, Vascular and Transplantation Surgery, University of Munich, Munich, Germany., Heidecke CD; Department of General, Visceral, Thoracic and Vascular Surgery, Universitätsmedizin Greifswald, Greifswald, Germany., Tomazic A; Department of Abdominal Surgery, University Medical Centre, Ljubljana, Slovenia., Halloran CM; NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK., Wilhelm TJ; Department of Surgery, University Medical Centre Mannheim (UMM), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Bahra M; Charité, Department of Surgery, CCM/CVK Berlin, Berlin, Germany., Beckurts T; Department of General, Visceral, Thoracic, and Trauma Surgery, Krankenhaus der Augustinerinnen, Cologne, Germany., Börner T; Department of Surgery, University Medical Center Regensburg, Regensburg, Germany., Glanemann M; Department for General, Visceral, Vascular, and Pediatric Surgery, Saarland University Hospital and Saarland University Faculty of Medicine, Homburg, Germany., Steger U; Department of General, Visceral, Vascular, and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany., Treitschke F; Department of General and Visceral Surgery, Red Cross Hospital Munich, Munich, Germany., Staib L; Department of General and Visceral Surgery, Klinikum Esslingen, Esslingen, Germany., Thelen K; Coordination Centre for Clinical Trials (KKS), University Hospital Heidelberg, Heidelberg, Germany., Bruckner T; Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany., Mihaljevic AL; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany; The Surgical Trial Network CHIR-Net, University of Heidelberg, Heidelberg, Germany., Werner J; Department of General, Visceral, Vascular and Transplantation Surgery, University of Munich, Munich, Germany., Ulrich A; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany., Hackert T; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany., Büchler MW; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany. Electronic address: markus.buechler@med.uni-heidelberg.de.
Publikováno v:
Lancet (London, England) [Lancet] 2017 Sep 09; Vol. 390 (10099), pp. 1027-1037.
Autor:
Cheng T; Department of Surgery, Technical University of Munich (TUM), Munich, Germany., Jian Z; Department of Surgery, Technical University of Munich (TUM), Munich, Germany., Li K; Institute of Clinical Chemistry and Pathobiochemistry, Munich, Germany., Raulefs S; Department of Surgery, Technical University of Munich (TUM), Munich, Germany., Regel I; Institute of Pathology, Heinrich-Heine-University, Duesseldorf, Germany., Shen S; Department of Gastroenterology, the Affiliated Drum Tower Hospital of Nanjing University, Medical School, Nanjing, Jiangsu, China., Zou X; Department of Gastroenterology, the Affiliated Drum Tower Hospital of Nanjing University, Medical School, Nanjing, Jiangsu, China., Ruland J; Institute of Clinical Chemistry and Pathobiochemistry, Munich, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Center for Infection Research (DZIF), Munich, Germany., Ceyhan GO; Department of Surgery, Technical University of Munich (TUM), Munich, Germany., Friess H; Department of Surgery, Technical University of Munich (TUM), Munich, Germany., Michalski CW; Department of Surgery, University of Heidelberg, Heidelberg, Germany., Kleeff J; NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK., Kong B; Department of Surgery, Technical University of Munich (TUM), Munich, Germany.; Department of Gastroenterology, the Affiliated Drum Tower Hospital of Nanjing University, Medical School, Nanjing, Jiangsu, China.
Publikováno v:
Oncogenesis [Oncogenesis] 2016 Dec 12; Vol. 5 (12), pp. e278. Date of Electronic Publication: 2016 Dec 12.
Autor:
Sabater L; Department of Surgery, Hospital Clinico, University of Valencia, Valencia, Spain †Department of Surgery, Complejo Hospitalario Universitario de Vigo, Vigo, Spain ‡Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands §Department of Gastroenterology, Consorci Sanitari de Terrassa, Terrassa, Spain ¶Department of Gastroenterology, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Spain ||Department of Surgery, Università Vita e Salute, Ospedale San Raffaele IRCCS, Milano, Italy **Department of Surgery, Institut de Malalties Digestives I Metabòliques, Hospital Clínic, IDIBAPS, Barcelona, Spain ††Department of Medicine, Pancreas Center, University of Verona, Verona, Italy ‡‡Department of Endocrinology and Nutrition, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain. §§Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden ¶¶Department of Surgery, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain. ||||Department of Surgery, Hospital Universitario de La Princesa, Madrid, Spain ***Department of Gastroenterology, Complejo Hospitalario de Navarra, Pamplona, Spain †††Unidad de Cirugía Hepato-bilio-pancreática y Trasplante, Hospital Universitari i Politecnic. La Fe, Valencia, Spain ‡‡‡NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK §§§Department of Gastroenterology, Hospital Clinico, University of Valencia, Valencia, Spain ¶¶¶Unit of Digestive Disease, Agencia Sanitaria Costa del Sol, Marbella, Málaga ||||||Department Digestive System, Sant'Orsola-Malpighi Hospital, Bologna, Italy ****Department of Surgery, Hospital Universitario de Guadalajara, Guadalajara, Spain ††††Department of HPB Surgery and Liver Transplantation, Hospital Carlos Haya, Malaga, Spain ‡‡‡‡Exocrine Pancreas Research Unit, Hospital Universitari Vall d'Hebron, Institut de Recerca, Universitat Autònoma de Barcelona, CIBEREHD, Barcelona, Spain §§§§Department of Digestive Surgery- Division of HBP Surgery, Hospital Universitario Donostia, San Sebastián, Spain ¶¶¶¶Department of Gastroenterology, Institut de Malalties Digestives i Metabòliques, Hospital Clínic, IDIBAPS, CiberEHD, Barcelona, Spain ||||||||Department of Gastroenterology, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain., Ausania F, Bakker OJ, Boadas J, Domínguez-Muñoz JE, Falconi M, Fernández-Cruz L, Frulloni L, González-Sánchez V, Lariño-Noia J, Lindkvist B, Lluís F, Morera-Ocón F, Martín-Pérez E, Marra-López C, Moya-Herraiz Á, Neoptolemos JP, Pascual I, Pérez-Aisa Á, Pezzilli R, Ramia JM, Sánchez B, Molero X, Ruiz-Montesinos I, Vaquero EC, de-Madaria E
Publikováno v:
Annals of surgery [Ann Surg] 2016 Dec; Vol. 264 (6), pp. 949-958.
Autor:
Kleeff J; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Costello E; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Jackson R; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Halloran C; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Greenhalf W; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Ghaneh P; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Lamb RF; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Lerch MM; Department of Medicine A, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany., Mayerle J; Department of Medicine A, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany., Palmer D; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Cox T; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Rawcliffe CL; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK., Strobel O; Department of Surgery, University of Heidelberg, Heidelberg, Germany., Büchler MW; Department of Surgery, University of Heidelberg, Heidelberg, Germany., Neoptolemos JP; Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK.; NIHR Pancreas Biomedical Research Unit, University of Liverpool, Liverpool L69 3GA, UK.
Publikováno v:
British journal of cancer [Br J Cancer] 2016 Sep 27; Vol. 115 (7), pp. 887-94. Date of Electronic Publication: 2016 Sep 01.
Autor:
Demir IE; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Tieftrunk E; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Schorn S; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Saricaoglu ÖC; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Pfitzinger PL; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Teller S; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Wang K; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Hepatic, Biliary & Pancreatic Surgery, Peking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing, China., Waldbaur C; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Kurkowski MU; Department of Internal Medicine II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Wörmann SM; Department of Internal Medicine II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Shaw VE; Department of Molecular and Clinical Cancer Medicine, The Liverpool Cancer Research UK Centre, Liverpool, UK., Kehl T; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Laschinger M; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Costello E; Department of Molecular and Clinical Cancer Medicine, The Liverpool Cancer Research UK Centre, Liverpool, UK Liverpool NIHR Pancreas Biomedical Research Unit, Liverpool, UK., Algül H; Department of Internal Medicine II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Friess H; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Ceyhan GO; Department of Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Publikováno v:
Gut [Gut] 2016 Jun; Vol. 65 (6), pp. 1001-14. Date of Electronic Publication: 2016 Jan 13.