Výsledky vyhledávání - "NICOLE TESSOT"

Akademický článek

Synthesis of the 4-desmethoxy analogue of RU79115

Autor: MICHEL KLICH, ANNE-MARIE PERIERS, NICOLE TESSOT, BRANISLAV MUSICKI

Publikováno v: Journal of the Serbian Chemical Society, Vol 69, Iss 11, Pp 855-859 (2004)

The synthesis, and biological activity in vitro of the 4-desmethoxy analogue (3) of RU 79115 (2) is described. Comparison of the biological activity of the two analogues clearly indicated the importance of the 4-methoxy group in conferring good gyras

Externí odkaz: https://doaj.org/article/0a369480a5814bbd8e469aee31d0a0b7

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Synthesis and Antibacterial Activity of Ketolides (6-O-Methyl-3-oxoerythromycin Derivatives): A New Class of Antibacterials Highly Potent Against Macrolide-Resistant and -Susceptible Respiratory Pathogens

Autor: Véronique Loyau, Alain Bonnefoy, Solange Gouin D'ambrieres, A Dussarat, Nicole Tessot, C. Fromentin, Sylvette Lachaud, Patrick Laurin, Jean-Michel Auger, Yannick Benedetti, Francois Bretin, J. F. Chantot, C. Agouridas, A. Denis, Le Martret Odile

Publikováno v: Journal of Medicinal Chemistry. 41:4080-4100

In the search for new antibiotics active against macrolide-resistant pneumococci and Haemophilus influenzae, we synthesized a new class of 3-oxo-6-O-methylerythromycin derivatives, so-called "ketolides". A keto function was introduced in position 3 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9a59ca094217e91a9cd1a14deb0276
https://doi.org/10.1021/jm980240d

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Improved antibacterial activities of coumarin antibiotics bearing 5',5'-dialkylnoviose: biological activity of RU79115

Autor: Nicole Tessot, Jacques Demassey, Periers Anne-Marie, Fabienne Chatreaux, Yannick Benedetti, Jean Khider, Patrick Laurin, Marlene Airault, Michel Klich, Alain Bonnefoy, Pascale Vicat, Branislav Musicki, Didier Ferroud, Patrice Lassaigne, Claudine Dupuis-Hamelin, Jean-Luc Haesslein, Christine Pierre, Alain Iltis, Sylvette Lachaud

Publikováno v: Bioorganicmedicinal chemistry letters. 10(15)

A new series of coumarin inhibitors of DNA gyrase B bearing a N-propargyloxycarbamate at C-3' of various 5',5'-dialkylnoviose, including RU79115, were synthesised and their antibacterial activities have been delineated. Introduction of dialkyl substi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc5a71cfbe94e9672b3fc999488bf53
https://pubmed.ncbi.nlm.nih.gov/10937727

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