Zobrazeno 1 - 10
of 815
pro vyhledávání: '"NICHOLAS A. PEPPAS"'
Autor:
Ethan P. Cisneros, Brinkley A. Morse, Ani Savk, Khyati Malik, Nicholas A. Peppas, Olivia L. Lanier
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-27 (2024)
Abstract Despite their potential, the adoption of nanotechnology in therapeutics remains limited, with only around eighty nanomedicines approved in the past 30 years. This disparity is partly due to the “one-size-fits-all” approach in medical des
Externí odkaz:
https://doaj.org/article/222eb4bcec4a4db18a65a92ad6ec468e
Autor:
Shankar Subramaniam, Metin Akay, Mark A. Anastasio, Vasudev Bailey, David Boas, Paolo Bonato, Ashutosh Chilkoti, Jennifer R. Cochran, Vicki Colvin, Tejal A. Desai, James S. Duncan, Frederick H. Epstein, Stephanie Fraley, Cecilia Giachelli, K. Jane Grande-Allen, Jordan Green, X. Edward Guo, Isaac B. Hilton, Jay D. Humphrey, Chris R Johnson, George Karniadakis, Michael R. King, Robert F. Kirsch, Sanjay Kumar, Cato T. Laurencin, Song Li, Richard L. Lieber, Nigel Lovell, Prashant Mali, Susan S. Margulies, David F. Meaney, Brenda Ogle, Bernhard Palsson, Nicholas A. Peppas, Eric J. Perreault, Rick Rabbitt, Lori A. Setton, Lonnie D. Shea, Sanjeev G. Shroff, Kirk Shung, Andreas S. Tolias, Marjolein C.H. van der Meulen, Shyni Varghese, Gordana Vunjak-Novakovic, John A. White, Raimond Winslow, Jianyi Zhang, Kun Zhang, Charles Zukoski, Michael I. Miller
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 1-13 (2024)
Over the past two decades Biomedical Engineering has emerged as a major discipline that bridges societal needs of human health care with the development of novel technologies. Every medical institution is now equipped at varying degrees of sophistica
Externí odkaz:
https://doaj.org/article/99aa19c8944b4368939a87375caa3abd
Autor:
Wei Liu, Yanfang Wang, Jinqiang Wang, Olivia L. Lanier, Marissa E. Wechsler, Nicholas A. Peppas, Zhen Gu
Publikováno v:
Engineering, Vol 13, Iss , Pp 53-70 (2022)
Macroencapsulation has been widely used in cell therapy due to its capability to provide immune-privileged sites for implanted allogeneic or xenogeneic cells. Macroencapsulation also serves to provide mechanical and physiochemical support for maintai
Externí odkaz:
https://doaj.org/article/cb3cfe53afe7462e95b8d7f3da83fa53
Autor:
Olivia L. Lanier, Edgar Pérez-Herrero, Abielle P. D.’ Andrea, Kiana Bahrami, Elaine Lee, Deidra M. Ward, Nilaya Ayala-Suárez, Sheyla M. Rodríguez-Méndez, Nicholas A. Peppas
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105326- (2022)
Summary: Hematological cancers such as leukemia, lymphoma, and multiple myeloma have traditionally been treated with chemo and radiotherapy approaches. Introduction of immunotherapies for treatment of these diseases has led to patient remissions that
Externí odkaz:
https://doaj.org/article/05fc9d272c73472a88be6571a831befe
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 8, Iss 2, Pp 147-164 (2018)
Therapeutic proteins and peptides have revolutionized treatment for a number of diseases, and the expected increase in macromolecule-based therapies brings a new set of challenges for the pharmaceutics field. Due to their poor stability, large molecu
Externí odkaz:
https://doaj.org/article/c0c43bf8002d4f1aafb75c733df10364
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 33:1324-1347
Tissue engineering is a multidisciplinary field that focuses on creating functional tissue through the combination of biomimetic scaffolds, a cell source, and biochemical/physiochemical cues. Stem cells are often used as the cell source due to their
Autor:
John R. Clegg, Nicholas A. Peppas
Publikováno v:
ACS Applied Materials & Interfaces.
Publikováno v:
Macromolecules
Increasingly accurate mathematical models have been developed to relate solute and hydrogel properties to solute diffusion coefficients in hydrogels, primarily by comparing solute sizes and hydrogel mesh sizes. Here, we use a standardized, high-throu
Autor:
James F. Reuther, Nicholas A. Peppas, Jordyn M. Wyse, Susana P. Simmonds, Kiana Bahrami, H. K. H. Jocelyn Dang, Eric V. Anslyn, Samuel D. Dahlhauser, Marissa E. Wechsler, Abigail N. VandeWalle
Publikováno v:
Nano Lett
Although dry eye is highly prevalent, many challenges exist in diagnosing the symptom and related diseases. For this reason, anionic hydrogel-coated gold nanoshells (AuNSs) were used in the development of a label-free biosensor for detection of high
Publikováno v:
Science advances. 8(47)
Cancer vaccines have attracted widespread interest in tumor therapy because of the potential to induce an effective antitumor immune response. However, many challenges including weak immunogenicity, off-target effects, and immunosuppressive microenvi