Zobrazeno 1 - 10
of 338
pro vyhledávání: '"NGS data"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Directed evolution is a powerful tool that can bypass gaps in our understanding of the sequence-function relationship of proteins and still isolate variants with desired activities, properties, and substrate specificities. The rise of directed evolut
Externí odkaz:
https://doaj.org/article/c1bc1e805d0a446b9d89e7f53b9ac9c8
Autor:
Magdalena Karwańska, Alina Wieliczko, Anders Miki Bojesen, Kasper Rømer Villumsen, Eva Krzyżewska-Dudek, Anna Woźniak-Biel
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-15 (2023)
Abstract Gallibacterium anatis biovar haemolytica is a bacterium that is frequently associated with infections of the reproductive tract and respiratory system in poultry. To assess the current prevalence and resistance profile of these bacteria in P
Externí odkaz:
https://doaj.org/article/80acfd87c0254078bb222a808d98bb65
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Backgroud CRISPR/Cas is an efficient genome editing system that has been widely used for functional genetic studies and exhibits high potential in biomedical translational applications. Indel analysis has thus become one of the most common p
Externí odkaz:
https://doaj.org/article/736e1a4a93474a9682b45485d78c5dd6
Publikováno v:
Food Chemistry: Molecular Sciences, Vol 7, Iss , Pp 100182- (2023)
Next-generation-sequencing (NGS) becomes increasingly important for laboratories tasked with the detection of genetically modified organisms (GMOs) in food, feed and seeds. Its implementation into standardized workflows demands reliable intra- and in
Externí odkaz:
https://doaj.org/article/72e55a17377a41f3931983cbb1fb9af0
Publikováno v:
Mathematics, Vol 12, Iss 3, p 420 (2024)
Copy number variation (CNV) has been increasingly recognized as a type of genomic/genetic variation that plays a critical role in driving human diseases and genomic diversity. CNV detection and analysis from cancer genomes could provide crucial infor
Externí odkaz:
https://doaj.org/article/f2f6bdfdb1c94c348eb453fea0fe171d
Akademický článek
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Autor:
Christian Vogeley, Thach Nguyen, Selina Woeste, Jean Krutmann, Thomas Haarmann-Stemmann, Andrea Rossi
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Transcriptome analysis experiments enable researchers to gain extensive insights into the molecular mechanisms underlying cell physiology and disease. Oxford Nanopore Technologies (ONT) has recently been developed as a fast, miniaturized, portable, a
Externí odkaz:
https://doaj.org/article/1dc9924d50894a9798481771054e0b0c
Autor:
Maria Zanti, Kyriaki Michailidou, Maria A. Loizidou, Christina Machattou, Panagiota Pirpa, Kyproula Christodoulou, George M. Spyrou, Kyriacos Kyriacou, Andreas Hadjisavvas
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract Background Next-generation sequencing (NGS) represents a significant advancement in clinical genetics. However, its use creates several technical, data interpretation and management challenges. It is essential to follow a consistent data ana
Externí odkaz:
https://doaj.org/article/2504d4d34e724e00946dd853e8e06165
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundDespite the new next-generation sequencing (NGS) molecular approaches implemented the genetic testing in clinical diagnosis, copy number variation (CNV) detection from NGS data remains difficult mainly in the absence of bioinformatics perso
Externí odkaz:
https://doaj.org/article/a09ca03b26e24bba9508542aa1b6cce3
Autor:
Emmanuelle Lerat
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Transposable elements (TEs) are recognized for their great impact on the functioning and evolution of their host genomes. They are associated to various deleterious effects, which has led to the evolution of regulatory epigenetic mechanisms to contro
Externí odkaz:
https://doaj.org/article/f9db45bea1dd4f58b2bd13be5d994a66