Zobrazeno 1 - 10
of 75
pro vyhledávání: '"NFkB signaling"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8907 (2024)
Sepsis is a severe condition induced by microbial infection. It elicits a systemic inflammatory response, leading to multi-organ failure, and the liver, as a scavenger, plays a significant role in this process. Controlling hepatic inflammation and ma
Externí odkaz:
https://doaj.org/article/a6dd152d57dd4a59ad7607705e19ab84
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22911- (2023)
Regulatory T cells (Tregs) play a central role in modulating adaptive immune responses in humans and mice. The precise biological role of non-canonical nuclear factor ‘κ-light-chain-enhancer’ of activated B cells (NFKB) signaling in human Tregs
Externí odkaz:
https://doaj.org/article/6e2671d589c24504a3b88d615b8c09d2
Akademický článek
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Autor:
Andrea Sánchez-Navarro, Miguel Ángel Martínez-Rojas, Adrián Albarrán-Godinez, Rosalba Pérez-Villalva, Johan Auwerx, Abigail de la Cruz, Lilia G. Noriega, Florencia Rosetti, Norma A. Bobadilla
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2573 (2022)
Acute kidney injury (AKI) is a public health problem worldwide. Sirtuins are a family of seven NAD+-dependent deacylases, Overexpression of Sirtuin 1, 3, and 5 protect against AKI. However, the role of Sirtuin 7 (Sirt7) in AKI is not known. Here, we
Externí odkaz:
https://doaj.org/article/c98d501ace064f0e87a2e65a2d0df6b5
Autor:
Kojo, Satoshi, Elly, Chris, Harada, Yohsuke, Langdon, Wallace Y., Kronenberg, Mitchell, Liu, Yun-Cai
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2009 Oct . 106(42), 17847-17851.
Externí odkaz:
https://www.jstor.org/stable/25592918
Autor:
Léa Décarie-Spain, Stephanie Fulton, Alexandre Fisette, Élizabeth Jacob-Brassard, David Lau, Cecile Hryhorczuk
Publikováno v:
Brain, Behavior, & Immunity-Health, Vol 16, Iss, Pp 100324-(2021)
Brain, Behavior, & Immunity-Health
Brain, Behavior, & Immunity-Health
Obesity significantly increases the risk for anxiety and depression. Our group has recently demonstrated a role for nucleus accumbens (NAc) pro-inflammatory nuclear factor kappa-B (NFkB) signaling in the development of anxiodepressive-like behaviors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c6eb62e7d090d2712844412fd8b765
http://www.sciencedirect.com/science/article/pii/S2666354621001277
http://www.sciencedirect.com/science/article/pii/S2666354621001277
Autor:
Chiara Sanguinetti, Silvana Cianchetti, Roberto Pedrinelli, Michele Lai, Alessandro Celi, Vittoria Carnicelli, Tommaso Neri, Valentina Scalise
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12640, p 12640 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12640
International Journal of Molecular Sciences, Vol 22, Iss 12640, p 12640 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12640
Proprotein convertase subtilisin kexin 9 (PCSK9) increases LDL cholesterol (C) concentration by accelerating the hepatic degradation of the LDL receptor (R) thus promoting atherogenesis. The molecule, however, also exerts proinflammatory effects inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0ef3d71f08e420d0debb53a4a43329
https://pubmed.ncbi.nlm.nih.gov/34884442
https://pubmed.ncbi.nlm.nih.gov/34884442
Autor:
Min-Su Han, Eun Ju Lee, Ji-Ae Jang, Gun Woo Kim, Hye-Ri Park, Seungwoo Han, Youn-Kwan Jung, Hyun-Jung Cho
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in articular cartilage and the loss of CS-GAG occurs early in OA. As a major component of perichondral matrix interacting directly with chondrocytes, the active turnover of CS can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1d8aed7422b1e7e3efa1f6f4b9b060
http://link.springer.com/article/10.1038/s41598-019-52358-4
http://link.springer.com/article/10.1038/s41598-019-52358-4
Autor:
Samuel G. Fernandes, Lucas G.A. Ferreira, Maria Christina W. Avellar, Fernanda A. Nishino, Barry T. Hinton, Camilla M. Ribeiro
Publikováno v:
Journal of reproductive immunology. 149
The Wolffian duct (WD) is an embryonic tissue that undergoes androgen-induced morphological changes to become the epididymis. Toll-like receptor 4 (TLR4)- and nuclear factor kB (NFKB)-induced effectors are expressed in the adult epididymis and repres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c897d15c4096b819055da3c9590585e
https://pubmed.ncbi.nlm.nih.gov/34915277
https://pubmed.ncbi.nlm.nih.gov/34915277
Autor:
Jingfeng Duan, Zhonglun Chen, Yue Heng, Jiacai Zuo, Mingjun Pu, Wei Wei, Yufeng Tang, Bufan Yang, Wenqiang Xin
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2021 (2021)
BioMed Research International, Vol 2021 (2021)
Stroke is an acute cerebrovascular disease, including ischemic and hemorrhagic stroke. Stroke is the second leading cause of death after ischemic heart disease, which accounts for 9% of the global death toll. To explore the molecular mechanisms of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7db137a88d3984f34bbfa7be911f02