Zobrazeno 1 - 10
of 38
pro vyhledávání: '"NFKBID"'
Autor:
Sharesta Khoenkhoen, Monika Ádori, Darío Solís-Sayago, Juliette Soulier, Jamie Russell, Bruce Beutler, Gabriel K. Pedersen, Gunilla B. Karlsson Hedestam
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mice lacking the atypical inhibitory kappa B (IκB) protein, IκBNS, a regulator of the NF-κB pathway encoded by the nfkbid gene, display impaired antibody responses to both T cell-independent (TI) and T cell-dependent (TD) antigens. To better under
Externí odkaz:
https://doaj.org/article/36af7d3f9d0c45939da9ec1ad035fe3f
Autor:
Monika Adori, Sharesta Khoenkhoen, Jingdian Zhang, Xaquin Castro Dopico, Gunilla B. Karlsson Hedestam
Publikováno v:
Cells, Vol 12, Iss 9, p 1229 (2023)
Lipopolysaccharide (LPS) stimulates dual receptor signaling by bridging the B cell receptor and Toll-like receptor 4 (BCR/TLR4). B cells from IκBNS-deficient bumble mice treated with LPS display reduced proliferative capacity and impaired plasma cel
Externí odkaz:
https://doaj.org/article/546a27a20fa44cefbf283fd5d066202e
Akademický článek
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Akademický článek
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Autor:
Jean L. Scholz, Monika Adori, Gabriel K. Pedersen, Michael P. Cancro, Sharesta Khoenkhoen, Elina Erikson, Gunilla B. Karlsson Hedestam, Julian M. Stark
Publikováno v:
Immunology and Cell Biology
Impaired classical NF‐κB pathway signaling causes reduced antibody responses to T‐independent (TI) antigens. We investigated the potential reasons for defective TI responses in mice lacking the atypical inhibitory kappa B (IκB) protein of the N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445d24db6b6fca43a588a67c31168ba4
https://doi.org/10.1111/imcb.12228
https://doi.org/10.1111/imcb.12228
Autor:
Gabriel Karlsson Pedersen, Monika eÁdori, julian M Stark, Sharesta eKhoenkhoen, Carrie eArnold, Bruce eBeutler, Gunilla B Karlsson Hedestam
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Mice deficient in central components of classical NF-κB signaling have low levels of circulating natural IgM antibodies and fail to respond to immunization with T-independent type 2 (TI-2) antigens. A plausible explanation for these defects is the s
Externí odkaz:
https://doaj.org/article/bd0a5a4cd77745c8b03f34ac929ac431
Akademický článek
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Autor:
Xiaohan Yao, Zhihai Qin, Ming Wang, Yuan Wang, Yan Yan, Jiajia Wan, Xixi Duan, Yanru Cheng, Lijing Zhang, Chen Ni, Cancan Du, Linyu Zhu
Publikováno v:
Journal of Cellular and Molecular Medicine
Tumour‐derived exosomes have been shown to induce pre‐metastatic niche formation, favoring metastatic colonization of tumour cells, but the underlying molecular mechanism is still not fully understood. In this study, we showed that exosomes deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b969ed204c6b1b40a2880ceef9bbf68a
https://pubmed.ncbi.nlm.nih.gov/32449597
https://pubmed.ncbi.nlm.nih.gov/32449597
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 57(7)
Exosomes are a type of extracellular vesicle that act as shuttles, transporting certain genetic information to other cells. MiRNA cargo within exosomes can regulate gene expression at the transcriptional level. The objective of this study was to inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f00b63ec1af22ee3f014eceb6afbb62
https://pubmed.ncbi.nlm.nih.gov/34312802
https://pubmed.ncbi.nlm.nih.gov/34312802
Autor:
Masaya Yokota, Kiyoshi Takeda, Koichi Hirose, Yusuke Yokoyama, Kotaro Suzuki, Hiroaki Takatori, Hiroshi Nakajima, Tomohiro Tamachi, Yuko Maezawa, Akira Suto
Publikováno v:
Allergy. 72:1043-1053
Background In allergic asthma, environmental allergens including house dust mite (HDM) trigger pattern recognition receptors and activate downstream signaling pathways including NF-κB pathways not only in immune cells but also in airway epithelial c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a290acfcf112e4a2c929dce8db49035d
https://doi.org/10.1111/all.13079
https://doi.org/10.1111/all.13079