Zobrazeno 1 - 8 of 8 pro vyhledávání: '"NF-kappa B/*immunology"'
1
A TLR7/8 Agonist-Including DOEPC-Based Cationic Liposome Formulation Mediates Its Adjuvanticity Through the Sustained Recruitment of Highly Activated Monocytes in a Type I IFN-Independent but NF-κB-Dependent Manner
Autor: Elodie Belnoue, Floriane Auderset, Paul-Henri Lambert, Claire-Anne Siegrist, Beatris Mastelic-Gavillet
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in immunology, Vol. 11 (2020) P. 580974
Novel adjuvants, such as Toll-like receptors (TLRs) agonists, are needed for the development of new formulations able to circumvent limitations of current vaccines. Among TLRs, TLR7/8 agonists represent promising candidates, as they are well describe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f1c233b620dd8097cc5e8f96b6438c
https://www.frontiersin.org/articles/10.3389/fimmu.2020.580974/full
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2
Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism
Autor: Souraya Sayegh, Oula El Atat, Katy Diallo, Benjamin Rauwel, Yannick Degboé, Etienne Cavaignac, Arnaud Constantin, Alain Cantagrel, Viviane Trak-Smayra, Nada Alaaeddine, Jean-Luc Davignon
Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, 2019, 10, pp.1482. ⟨10.3389/fimmu.2019.01482⟩
International audience; Introduction: Adipose-derived mesenchymal stem cells (ADSC) have been shown to have remarkable immune-modulating effects. However, their efficacy in clinical trials has yet to be fully demonstrated. This could be due to a lack
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105a9338af9097f15184707f1e63ad29
http://europepmc.org/articles/PMC6710434
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3
Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis
Autor: Mindy Tsai, Nicolas Gaudenzio, Axel Roers, See-Ying Tam, Yuko Kawakami, Pierre Chambon, Philipp Starkl, Dimitri Pirottin, Stephen J. Galli, Sophie El Abbas, Jinah Kim, Nadine Antoine, Fabrice Bureau, Oliwia W Zurek, Laurent L. Reber, Toshiaki Kawakami, Thomas Marichal, Riccardo Sibilano
Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, 2016, 126 (12), pp.4497-4515. ⟨10.1172/JCI86359⟩
International audience; Epidermal keratinocytes form a structural and immune barrier that is essential for skin homeostasis. However, the mechanisms that regulate epidermal barrier function are incompletely understood. Here we have found that keratin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542066fd135b8c7de9d713b77f413dc3
https://doi.org/10.1172/jci86359
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4
Holding All the CARDs: How MALT1 Controls CARMA/CARD-Dependent Signaling
Autor: Juilland, M., Thome, M.
Publikováno v: Frontiers in immunology, vol. 9, pp. 1927
The scaffold proteins CARMA1-3 (encoded by the genes CARD11, -14 and -10) and CARD9 play major roles in signaling downstream of receptors with immunoreceptor tyrosine activation motifs (ITAMs), G-protein coupled receptors (GPCR) and receptor tyrosine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1900::8d78291d5c1e5e91f3e36b59bf85c7e4
https://serval.unil.ch/notice/serval:BIB_7A5968ADA94D
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5
Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation
Autor: Daniel Sauter, Carine Van Lint, Benoît Van Driessche, Elisabeth Reith, Ali Gawanbacht, Nadia Rahm, Dominik Hotter, Teresa Krabbe, Martine Peeters, Frank Kirchhoff, Ahidjo Ayouba
Publikováno v: PLoS pathogens, vol. 13, no. 8, pp. e1006598
PLoS Pathogens, Vol 13, Iss 8, p e1006598 (2017)
PLoS Pathogens
P L o S Pathogens, 13 (8
Primate lentiviruses have evolved sophisticated strategies to suppress the immune response of their host species. For example, HIV-2 and most simian immunodeficiency viruses (SIVs) use their accessory protein Nef to prevent T cell activation and anti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f105e632aee51d4dd08c6e780d401ec6
https://serval.unil.ch/resource/serval:BIB_ECD230868D0D.P001/REF.pdf
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6
Amelioration of endotoxin-induced uveitis treated with an IκB kinase β inhibitor in rats
Autor: Lennikov, Anton, Kitaichi, Nobuyoshi, Noda, Kousuke, Ando, Ryo, Dong, Zhenyu, Fukuhara, Junichi, Kinoshita, Satoshi, Namba, Kenichi, Mizutani, Miho, Fujikawa, Tomoyuki, Itai, Akiko, Ohno, Shigeaki, Ishida, Susumu
Publikováno v: Molecular Vision
Purpose: Endotoxin-induced uveitis (EIU) is an animal model for acute ocular inflammation. Several substances play major roles in the development of inflammatory changes in EIU, including tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7f2253e3dfdf604a216edf84f8b74d46
http://europepmc.org/articles/PMC3482174
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8
Transcription factor NF-kappa B is activated in microglia during experimental autoimmune encephalomyelitis
Autor: Kaltschmidt, Christian, Kaltschmidt, Barbara, Lannes-Vieira, J., Kreutzberg, G. W., Wekerle, H., Baeuerle, P. A., Gehrmann, J.
NF-kappa B is an inducible transcription factor involved in the induction of multiple genes during inflammatory processes. So far the information pertaining to the role of NF-kappa B in autoimmune processes has been restricted to in vitro analysis. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2294::1c7102350edcedd46d1dbdc4fedd9db6
https://pub.uni-bielefeld.de/record/2398807
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