Zobrazeno 1 - 10
of 7 502
pro vyhledávání: '"NF-kB"'
Autor:
Atteia Hebatallah Husseini, Gharib Amal F., Asker Mervat El-Sayed, Arafa Manar Hamed, Sakr Amr Tawfik
Publikováno v:
Open Chemistry, Vol 22, Iss 1, Pp 1111-34 (2024)
Externí odkaz:
https://doaj.org/article/503fe8640aa74acda22fd80e57c14b86
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 9215-9233 (2024)
The thymus, a central lymphoid organ in animals, serves as the site for T cell development, differentiation and maturation, vital to adaptive immunity. The thymus is critical for maintaining tissue homeostasis to protect against tumors and tissue dam
Externí odkaz:
https://doaj.org/article/0050ab48368b47eb8fff14ce6dfc3439
Autor:
Maria Georgiadou, George Notas, Ioannis Tsomidis, Argyro Voumbouraki, Ioannis Drygiannakis, George Emmanouil, Elias Kouroumalis
Publikováno v:
Gastroenterology Insights, Vol 15, Iss 3, Pp 614-631 (2024)
The anti-tumoral activity of somatostatin has been demonstrated in both animal experiments and human tumors. Clinical trials have reported conflicting results. We therefore hypothesized that somatostatin might have different effects in various hepato
Externí odkaz:
https://doaj.org/article/2d9b837cf3594f3987a22456e3af7c6c
Autor:
Rahma Tharwat Sabra, Amany Abdlrehim Bekhit, Nourhan Tharwat Sabra, Nadia Ahmed Abd El-Moeze, Moustafa Fathy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Sepsis is a potential fetal organ destruction brought on through an overzealous immunologic reaction to infection, causing severe inflammation, septic shock, and damage to different organs. Although there has been progress in the identificat
Externí odkaz:
https://doaj.org/article/29ab80bce01e4e178f3beecc16fdbf5e
Autor:
Chenyu Zhang, Volodymyr Gerzanich, Ruth Cruz-Cosme, Jiantao Zhang, Orest Tsymbalyuk, Cigdem Tosun, Bhargava Teja Sallapalli, Dongxiao Liu, Kaspar Keledjian, John C. Papadimitriou, Cinthia B. Drachenberg, Mohamed Nasr, Yanjin Zhang, Qiyi Tang, J. Marc Simard, Richard Y. Zhao
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT The primary challenge posed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is COVID-19-related mortality, often exacerbated by additional medical complications, such as COVID-19-associated kidney injuries (CAKIs).
Externí odkaz:
https://doaj.org/article/900650a8a1e74d1dae1d954fd7e47921
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Lentiviruses encode a number of multi-functional accessory proteins, however, the primary role of the accessory protein Vpr remains unclear. As Vpr engages the host DNA damage response (DDR) at multiple steps, modulation of the DDR is consid
Externí odkaz:
https://doaj.org/article/39e8f78aaadb449b8c28ac5585275194
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ferroptosis is an iron-dependent form of cell death, which finally culminates in lipid peroxidation and membrane damage. During the past decade, the interest in ferroptosis increased substantially and various regulatory components were discovered. Th
Externí odkaz:
https://doaj.org/article/ab6f33bf92b249c7a681cc9fb5c1f723
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract In the face of recent advances in Cervical cancer (CC) treatment, therapeutic and surgical procedures for CC management are still inadequate. In the current study for the first time Andrographolide (Andro) has been explored for its multitarg
Externí odkaz:
https://doaj.org/article/e58da0f6382f4b948332ad043050c0d7
Autor:
Do Manh Cuong, Sun Hee Yang, Ji Soo Kim, Jeong Yong Moon, Jongkeun Choi, Gyung Min Go, Somi Kim Cho
Publikováno v:
Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-15 (2024)
Abstract Increased production of reactive oxygen species (ROS) leads to oxidative stress, with its damaging effect extending to the mitochondria and plasma membrane. Further, prolonged inflammation can result in chronic disease development. The marin
Externí odkaz:
https://doaj.org/article/b6db9d5411de4e278b33510cff7f44bf
Autor:
Eric L. Garcia, Rebecca E. Steiner, Amanda C. Raimer, Laura E. Herring, A. Gregory Matera, Ashlyn M. Spring
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Spinal muscular atrophy (SMA) is a devastating neuromuscular disease caused by hypomorphic loss of function in the survival motor neuron (SMN) protein. SMA presents across a broad spectrum of disease severity. Unfortunately, genet
Externí odkaz:
https://doaj.org/article/36f3f1bc6c894a5db9335516db4577d4