Zobrazeno 1 - 10
of 73 728
pro vyhledávání: '"NF-κb"'
Autor:
Jianjun Feng, Xinwei Peng, Peng Lin, Yilei Wang, Ziping Zhang, Yuankai Xu, Pengfei Zou, Xiaojian Lai, Pengyun Chen, Tianyu Wang
Publikováno v:
Aquaculture and Fisheries, Vol 9, Iss 6, Pp 908-920 (2024)
IKKε is an IκB kinase participating in the control of NF-κB and type I IFN signal pathways in mammals. However, the function of IKKε in regulating immune response is largely unknown in teleost. Herein, an IKKε homologue named AjIKKε was charact
Externí odkaz:
https://doaj.org/article/e4c42fe394144d04b97d7ec7e84fddf7
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 11, Pp 1769-1773 (2024)
Nuclear factor kappa-B(NF-κB), an intricate nuclear transcription factor, is ubiquitously present within the myriad tissues and cells of the human corpus, engaging in a multiplicity of biological processes such as the development of the immune syste
Externí odkaz:
https://doaj.org/article/7d0aaf01b3e44c15ba7c0656078f75d5
Autor:
Vivek K. Kashyap, Prashanth K.B. Nagesh, Ajay K. Singh, Andrew Massey, Godwin P. Darkwah, Aaron George, Sheema Khan, Bilal B. Hafeez, Nadeem Zafar, Santosh Kumar, Namita Sinha, Murali M. Yallapu, Meena Jaggi, Subhash C. Chauhan
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background High-risk strains of HPV are known to cause cervical cancer. Multiple clinical studies have emphasized that smoking and drinking are critical risk factors for cervical cancer and its high-grade precursors. In this study, we invest
Externí odkaz:
https://doaj.org/article/7ed1d8a2c46143618f745a2c0c6f9c2b
Autor:
Peiwei Zhao, Qingjie Meng, Yali Wu, Lei Zhang, Xiankai Zhang, Li Tan, Yan Ding, XiaoXia Lu, Xuelian He
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Immunodeficiency 11B with atopic dermatitis (IMD11B, OMIM:617638) is rare primary immunodeficiency disease caused by germline dominant negative (DN) mutations in the CARD11 gene. Affected patients present with immune dysfunction, recurrent i
Externí odkaz:
https://doaj.org/article/d85b2dc6efba4233b333bbfa5d5cef86
Autor:
Xiaowen Huang, Pengju Wei, Cheng Fang, Min Yu, Shilun Yang, Linhui Qiu, Yu Wang, Aimin Xu, Ruby Lai Chong Hoo, Junlei Chang
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract The blood-brain barrier (BBB) is a critical interface that maintains the central nervous system homeostasis by controlling the exchange of substances between the blood and the brain. Disruption of the BBB plays a vital role in the developmen
Externí odkaz:
https://doaj.org/article/b51dc661b9f841bcb71c732f4338d00d
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Background: Histone deacetylase 4 (HDAC4) and histone deacetylase 5 (HDAC5) are two isoforms of class IIa HDACs, and LMK235 is an HDAC inhibitor with higher selectivity for HDAC4/5. This study aimed to explore the expression and subcellular
Externí odkaz:
https://doaj.org/article/6cfadd4f34824f219325a01672b312d5
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The objective of this study was to investigate the correlation between Rab10 (GTP binding protein RAB10), TLR4 (Toll-like receptor 4), and NF-κB (nuclear factor kappa-B) levels and therapeutic effects in peripheral blood of patients with br
Externí odkaz:
https://doaj.org/article/149e6f4f51a2498f8c94bd450a16f834
Autor:
Hui Yang, Zhiyao Wang, Lixin Li, Xing Wang, Xian Wei, Shan Gou, Zimo Ding, Zhihui Cai, Qinjie Ling, Peter R. Hoffmann, Jingjun He, Fei Liu, Zhi Huang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Impaired intestinal homeostasis is a major pathological feature of inflammatory bowel diseases (IBD). Mannose and selenium (Se) both demonstrate potential anti-inflammatory and anti-oxidative properties. However, most lectin receptors bind f
Externí odkaz:
https://doaj.org/article/3011b1a1ce1d44408dcc5f6322f095eb
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 7261-7274 (2024)
Yin-shan Jin,* Yuan-qing Cui,* Yan-ping Xu,* Jie Chen, Xue-bao Zhang, Xiong Wang Department of Reproductive Medicine, Yantai Yuhuangding Hospital, Yantai, 264000, People’s Republic of China*These authors contributed equally to this
Externí odkaz:
https://doaj.org/article/2950e1557f5048e0b52667358fcee442
Autor:
Tongtong Xue, Qianyi Zhang, Tiantian Zhang, Lingxin Meng, Jing Liu, Dan Chai, Yuming Liu, Zhongyi Yang, Ran Jiao, Yunyao Cui, Jingjing Gao, Xiaohe Li, Aiguo Xu, Honggang Zhou
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Acute lung injury (ALI) is the result of damage to the capillary endothelia and the alveolar epithelial cell caused by various direct and indirect factors, leading to significant pulmonary interstitial and alveolar edema and acute hypoxic re
Externí odkaz:
https://doaj.org/article/9086ce84774b4ff080b8ab6f44bcddc4