Zobrazeno 1 - 10
of 4 395
pro vyhledávání: '"NF-κB Signaling"'
Autor:
Chen Jin, Fei Zhang, Hailang Luo, Boyang Li, Xue Jiang, Christopher J. Pirozzi, Chaozhao Liang, Meng Zhang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background and objective Chronic prostatitis (CP) is a condition markered by persistent prostate inflammation, yet the specific cytokines driving its progression remain largely undefined. This study aims to identify key cytokines involved in
Externí odkaz:
https://doaj.org/article/6fb8dabfef274c6b9babe1d8476d66c6
Autor:
Xiaohua Luo, Xiaopei Guo, Ningning Chen, Rui Peng, Ci Pan, Zhuyin Li, Bing Zhao, Ruonan Ji, Siyu Li
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Background Preeclampsia (PE) is a severe pregnancy complication characterized by complex molecular interactions. Understanding these interactions is crucial for developing effective therapeutic strategies. Methods This study applies a pharma
Externí odkaz:
https://doaj.org/article/8d7a1f0d4b3c490d8ed8c7fac6ddf934
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Acute pancreatitis (AP) is an inflammatory condition with potentially life-threatening complications. This study investigates the therapeutic potential of Clostridium butyricum for modulating the inflammatory cascade through the A
Externí odkaz:
https://doaj.org/article/8ffce7868b944fa58f3342679a66f06c
Publikováno v:
口腔疾病防治, Vol 32, Iss 11, Pp 886-893 (2024)
The irreversible destruction of periodontal tissue caused by periodontitis is the result of an imbalance between external pathogenic factors and the internal immune response. As human immune cells, macrophages have both pro- and anti-inflammatory rol
Externí odkaz:
https://doaj.org/article/8bbd42e6119e406d83989269e3e15cfe
Autor:
Duško Lainšček, Simon Horvat, Klemen Dolinar, Filip Ivanovski, Rok Romih, Sergej Pirkmajer, Roman Jerala, Mateja Manček-Keber
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Various signaling pathways are essential for both the innate immune response and the maintenance of cell homeostasis, requiring coordinated interactions among them. In this study, a mutation in the caspase-1 recognition site within MyD88 abo
Externí odkaz:
https://doaj.org/article/a0262ff384b84a5ebcc836f4d93183e9
Autor:
Guoqing Zhang, Yang Jiang, Zhichao Wang, Zhengting Guo, Jinpeng Hu, Xinqiao Li, Yongfeng Wang, Zhitao Jing
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Glioblastoma (GBM) is the most lethal and common primary tumor of central nervous system with a poor prognosis. Glioma stem cells (GSCs) are particularly significant in GBM proliferation, invasion, self-renewal and recurrence. Circular RNAs
Externí odkaz:
https://doaj.org/article/4e38aadc5b85450cb41827fafc578096
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 11, Pp 1769-1773 (2024)
Nuclear factor kappa-B(NF-κB), an intricate nuclear transcription factor, is ubiquitously present within the myriad tissues and cells of the human corpus, engaging in a multiplicity of biological processes such as the development of the immune syste
Externí odkaz:
https://doaj.org/article/7d0aaf01b3e44c15ba7c0656078f75d5
Autor:
Jialin Chen, Renwang Sheng, Qingyun Mo, Ludvig J. Backman, Zhiyuan Lu, Qiuzi Long, Zhixuan Chen, Zhicheng Cao, Yanan Zhang, Chuanquan Liu, Haotian Zheng, Yu Qi, Mumin Cao, Yunfeng Rui, Wei Zhang
Publikováno v:
Bioactive Materials, Vol 44, Iss , Pp 319-338 (2025)
Tendon repair remains challenging due to its poor intrinsic healing capacity, and stem cell therapy has emerged as a promising strategy to promote tendon regeneration. Nevertheless, the inflammatory environment following acute tendon injuries disrupt
Externí odkaz:
https://doaj.org/article/d6601ff863ad48069e4c155fd20cd778
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Objectives Circadian rhythm disruption (CRD) is implicated with numerous gastrointestinal motility diseases, with the enteric nervous system (ENS) taking main responsibility for the coordination of gastrointestinal motility. The purpose of t
Externí odkaz:
https://doaj.org/article/d7438ca91f6348229b71d8c376a1050b
Publikováno v:
Journal of Orthopaedic Translation, Vol 48, Iss , Pp 133-145 (2024)
Background: Spinal cord injuries (SCIs) trigger a cascade of detrimental processes, encompassing neuroinflammation and oxidative stress (OS), ultimately leading to neuronal damage. Phillygenin (PHI), isolated from forsythia, is used in a number of bi
Externí odkaz:
https://doaj.org/article/37dfb9e365cd468697cbcac6c239a063