Zobrazeno 1 - 10
of 7 559
pro vyhledávání: '"NF‐kB"'
Publikováno v:
Clinical Immunology Communications, Vol 6, Iss , Pp 15-25 (2024)
Mutations in NF-κB-related molecules result in combined immunodeficiency characterized by recurrent infection. In this study, we aimed to investigate the association between mutations in NF-κB family members, RELA, RELB, and RELC, and regulatory T
Externí odkaz:
https://doaj.org/article/2ddb4da3ab984092ab6cf56b19509537
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Several Genome Wide linkage Studies on psoriasis performed to gain insight of genetic architecture of the disease. Caspase Recruitment Domain-containing family 14 (CARD14) also known as CARMA2 or BIMP2; cytogenic location: 17q25.3, is a scaf
Externí odkaz:
https://doaj.org/article/0b5f98d59c224ef0b764de68809f2375
Autor:
Atteia Hebatallah Husseini, Gharib Amal F., Asker Mervat El-Sayed, Arafa Manar Hamed, Sakr Amr Tawfik
Publikováno v:
Open Chemistry, Vol 22, Iss 1, Pp 1111-34 (2024)
Externí odkaz:
https://doaj.org/article/503fe8640aa74acda22fd80e57c14b86
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 9215-9233 (2024)
The thymus, a central lymphoid organ in animals, serves as the site for T cell development, differentiation and maturation, vital to adaptive immunity. The thymus is critical for maintaining tissue homeostasis to protect against tumors and tissue dam
Externí odkaz:
https://doaj.org/article/0050ab48368b47eb8fff14ce6dfc3439
Autor:
Jie Yu, Wenke Cai, Tao Zhou, Bo Men, Shunqiong Chen, Dong Tu, Wei Guo, Jicui Wang, Feipeng Zhao, Yan Wang
Publikováno v:
Biochemistry and Biophysics Reports, Vol 40, Iss , Pp 101833- (2024)
Background: Lung cancer causes significant mortality, with invasion and metastasis being the main features that cause most cancer deaths. Lymph node metastasis is the primary metastatic route in non-small cell carcinoma (NSCLC) and influences the sta
Externí odkaz:
https://doaj.org/article/177035ec3a55411084066e3e31fd4c9d
Autor:
Giovanni Musso, Mella Alberto, Filippo Mariano, Maurizio Cassader, Franco De Michieli, Antonella Riva, Giovanna Petrangolini, Stefano Togni, Silvia Pinach, Roberto Gambino
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
We investigate the role of homeostatic mechanisms involved in acute, postprandial nutrient metabolism and nutrient-induced systemic inflammation in CKD presence and progression in Metabolic dysfunction-associated steatohepatitis (MASH). We assessed p
Externí odkaz:
https://doaj.org/article/27aee9611363417ea5dc3b9b2ee08c80
Autor:
Ahmed Z. Alanazi, Mohammed Alqinyah, Abdullah S. Alhamed, Hanan Mohammed, Mohammad Raish, Khaldoon Aljerian, Jawza F. Alsabhan, Khalid Alhazzani
Publikováno v:
Redox Report, Vol 29, Iss 1 (2024)
As a consequence of chronic hyperglycemia, diabetes complications and tissue damage are exacerbated. There is evidence that natural phytochemicals, including resveratrol, a bioactive polyphenol, may be able to reduce oxidative stress and improve insu
Externí odkaz:
https://doaj.org/article/1e3760820f444731a5047665d3e31ba0
Autor:
Chenyu Zhang, Volodymyr Gerzanich, Ruth Cruz-Cosme, Jiantao Zhang, Orest Tsymbalyuk, Cigdem Tosun, Bhargava Teja Sallapalli, Dongxiao Liu, Kaspar Keledjian, John C. Papadimitriou, Cinthia B. Drachenberg, Mohamed Nasr, Yanjin Zhang, Qiyi Tang, J. Marc Simard, Richard Y. Zhao
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT The primary challenge posed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is COVID-19-related mortality, often exacerbated by additional medical complications, such as COVID-19-associated kidney injuries (CAKIs).
Externí odkaz:
https://doaj.org/article/900650a8a1e74d1dae1d954fd7e47921
Autor:
Maria Georgiadou, George Notas, Ioannis Tsomidis, Argyro Voumbouraki, Ioannis Drygiannakis, George Emmanouil, Elias Kouroumalis
Publikováno v:
Gastroenterology Insights, Vol 15, Iss 3, Pp 614-631 (2024)
The anti-tumoral activity of somatostatin has been demonstrated in both animal experiments and human tumors. Clinical trials have reported conflicting results. We therefore hypothesized that somatostatin might have different effects in various hepato
Externí odkaz:
https://doaj.org/article/2d9b837cf3594f3987a22456e3af7c6c
Autor:
Rahma Tharwat Sabra, Amany Abdlrehim Bekhit, Nourhan Tharwat Sabra, Nadia Ahmed Abd El-Moeze, Moustafa Fathy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Sepsis is a potential fetal organ destruction brought on through an overzealous immunologic reaction to infection, causing severe inflammation, septic shock, and damage to different organs. Although there has been progress in the identificat
Externí odkaz:
https://doaj.org/article/29ab80bce01e4e178f3beecc16fdbf5e