Zobrazeno 1 - 10
of 2 515
pro vyhledávání: '"NEURAL PROGENITORS"'
Autor:
Aaron Stahl, Johanna Heider, Richard Wüst, Andreas J. Fallgatter, Katja Schenke-Layland, Hansjürgen Volkmer, Markus F. Templin
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Schizophrenia (SCZ) is a severe psychiatric disorder associated with alterations in early brain development. Details of underlying pathomechanisms remain unclear, despite genome and transcriptome studies providing evidence for abe
Externí odkaz:
https://doaj.org/article/51489a1947494cdb8ff5ce2b001fdb76
Autor:
Arjun Rajan, Ryann M. Fame
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106550- (2024)
Bioenergetics describe the biochemical processes responsible for energy supply in organisms. When these changes become dysregulated in brain development, multiple neurodevelopmental diseases can occur, implicating bioenergetics as key regulators of n
Externí odkaz:
https://doaj.org/article/37d9a72a147f44d28555f3b5765a7bb4
Autor:
Marielle Cochet, François Piumi, Kamila Gorna, Noémie Berry, Gaëlle Gonzalez, Anne Danckaert, Nathalie Aulner, Odile Blanchet, Stéphan Zientara, Francesc Xavier Donadeu, Hélène Munier-Lehmann, Jennifer Richardson, Alexandra Benchoua, Muriel Coulpier
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-13 (2024)
Abstract Outbreaks of West Nile virus (WNV) occur periodically, affecting both human and equine populations. There are no vaccines for humans, and those commercialised for horses do not have sufficient coverage. Specific antiviral treatments do not e
Externí odkaz:
https://doaj.org/article/9abdc7c7e2dd41c3a67553e709f9713f
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
This review delves into the generation and therapeutic applications of mesenchymal stem cell-derived neural progenitors (MSC-NPs) in Multiple Sclerosis (MS), a chronic autoimmune disease characterized by demyelination, neuroinflammation, and progress
Externí odkaz:
https://doaj.org/article/1e8517aefd7743eebe6e3f1dd60d2f8d
Autor:
Yassine Messat, Marta Martin-Fernandez, Said Assou, Keshi Chung, Frederic Guérin, Csilla Gergely, Frederic Cuisinier, Azel Zine
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9115 (2024)
The degeneration of spiral ganglion neurons (SGNs), which convey auditory signals from hair cells to the brain, can be a primary cause of sensorineural hearing loss (SNHL) or can occur secondary to hair cell loss. Emerging therapies for SNHL include
Externí odkaz:
https://doaj.org/article/c1cf24eef4434631b9079e9bd1f81537
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Tissue growth and morphogenesis are interrelated processes, whose tight coordination is essential for the production of different cell fates and the timely precise allocation of stem cell capacities. The zebrafish embryonic brainstem, the hindbrain,
Externí odkaz:
https://doaj.org/article/98e9fabdd36d4e22854ac70c0b4e9ce1
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 12, Pp 6104-6116 (2022)
Researching the technology for in vitro differentiation of embryonic stem cells (ESCs) into neural lineages is very important in developmental biology, regenerative medicine, and cell therapy. Thus, studies on in vitro differentiation of ESCs into ne
Externí odkaz:
https://doaj.org/article/3d1d2dba34e5471aa424333051c640e5
Autor:
Gabriella Ferretti, Alessia Romano, Rossana Sirabella, Sara Serafini, Thorsten Jürgen Maier, Carmela Matrone
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Background Semaphorins (Sema) belong to a large family of repellent guidance cues instrumental in guiding axons during development. In particular, Class 3 Sema (Sema 3) is among the best characterized Sema family members and the only produce
Externí odkaz:
https://doaj.org/article/04b5148a2c8848eca02cf56c61f631a5
Autor:
Pragnya Chakraborty, Bipan Kumar Deb, Vikas Arige, Thasneem Musthafa, Sundeep Malik, David I Yule, Colin W Taylor, Gaiti Hasan
Publikováno v:
eLife, Vol 12 (2023)
Loss of endoplasmic reticular (ER) Ca2+ activates store-operated Ca2+ entry (SOCE) by causing the ER localized Ca2+ sensor STIM to unfurl domains that activate Orai channels in the plasma membrane at membrane contact sites (MCS). Here, we demonstrate
Externí odkaz:
https://doaj.org/article/cb7de2cdcce24cca9ec2a6b6302e1887