Zobrazeno 1 - 10
of 38
pro vyhledávání: '"NET, Neutrophil Extracellular Trap"'
Autor:
Hooman D. Poor
Publikováno v:
Chest
Coronavirus disease 2019 (COVID-19), the disease responsible for the devastating pandemic that began at the end of 2019, has been associated with a significantly increased risk of pulmonary thrombosis, even in patients receiving prophylactic anticoag
Autor:
Lorena Rodríguez-González, Cristina Serrano del Castillo, Javier Flandes, Iker Fernández, María López-Álvarez, Juan Martínez-Milla, Ana-Maria Ioan, Valentin Fuster, Borja Ibanez, Carlos Galán-Arriola, Sandra Gómez-Talavera, Arnoldo Santos, César Pérez-Calvo, Agustín Clemente-Moragón, Eduardo Oliver
Publikováno v:
Journal of the American College of Cardiology
Background Severe coronavirus disease-2019 (COVID-19) can progress to an acute respiratory distress syndrome (ARDS), which involves alveolar infiltration by activated neutrophils. The beta-blocker metoprolol has been shown to ameliorate exacerbated i
Publikováno v:
Cytokine & Growth Factor Reviews
Highlights • COVID-19-associated coagulopathy is a leading cause of patient morbidity and multisystem organ failure in COVID-19 patients. • The pathogenesis of COVID-19-associated coagulopathy be attributed to endotheliitis and vessel wall abnorm
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 321-333 (2021)
Drury, B, Hardisty, G, Gray, R D & Ho, G 2021, ' Neutrophil Extracellular Traps in Inflammatory Bowel Disease: Pathogenic Mechanisms and Clinical Translation ', Cellular and Molecular Gastroenterology and Hepatology . https://doi.org/10.1016/j.jcmgh.2021.03.002
Cellular and Molecular Gastroenterology and Hepatology
Drury, B, Hardisty, G, Gray, R D & Ho, G 2021, ' Neutrophil Extracellular Traps in Inflammatory Bowel Disease: Pathogenic Mechanisms and Clinical Translation ', Cellular and Molecular Gastroenterology and Hepatology . https://doi.org/10.1016/j.jcmgh.2021.03.002
Cellular and Molecular Gastroenterology and Hepatology
The Inflammatory Bowel Diseases (IBD), Ulcerative Colitis (UC) and Crohn’s Disease (CD) are characterised by chronic non-resolving gut mucosal inflammation involving innate and adaptive immune responses. Neutrophils, usually regarded as first respo
Publikováno v:
The Journal of Biological Chemistry
Various forms of fibrosis, comprising tissue thickening and scarring, are involved in 40% of deaths across the world. Since the discovery of scarless functional healing in fetuses prior to a certain stage of development, scientists have attempted to
Autor:
Alexey A. Martyanov, Anna E. Boldova, Maria G. Stepanyan, Olga I. An, Alexander S. Gur'ev, Darya V. Kassina, Alexey Y. Volkov, Alexandr V. Balatskiy, Andrei A. Butylin, Sergei S. Karamzin, Elena V. Filimonova, Sergei V. Tsarenko, Sergei A. Roumiantsev, Alexander G. Rumyantsev, Mikhail A. Panteleev, Fazoil I. Ataullakhanov, Anastasia N. Sveshnikova
Publikováno v:
Thrombosis Research
Introduction Defects of platelet functional responses in COVID-19 were reported, but their origin and pathophysiological significance are unclear. The objective of this study was to characterize the thrombocytopathy in COVID-19. Materials and methods
Publikováno v:
Molecular Aspects of Medicine
Neutrophils are versatile immune effector cells essential for mounting a first-line defense against invading pathogens. However, uncontrolled activation can lead to severe life-threatening complications. Neutrophils exist as a heterogeneous populatio
Autor:
Cuiting Luo, Calvin W. L. Chin, Michael R. Zile, Bo Bai, Weiping Han, Wan Ting Tay, Yanyun Fu, Yu Wang, Jayantha Gunaratne, Philip Lee, Wulin Yang, Hannah Lee Foon, Kangmin Yang, Carolyn S.P. Lam, Aimin Xu
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 924-937 (2019)
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 924-937 (2019)
Visual Abstract
Highlights • The lean diabetic SKO mouse represents a novel and validated murine model of HFpEF. • The SKO HFpEF mouse model recapitulates the cardiac structure and function abnormalities in lean diabetic HFpEF patients in As
Highlights • The lean diabetic SKO mouse represents a novel and validated murine model of HFpEF. • The SKO HFpEF mouse model recapitulates the cardiac structure and function abnormalities in lean diabetic HFpEF patients in As
Publikováno v:
Molecular Immunology
Highlights • Neutrophils play important roles throughout the metastatic process. • Tumour progression and invasion are influenced by infiltrating neutrophils. • Signalling from neutrophils can enhance survival of circulating tumour cells. • N
Autor:
Tarek Z Aridi, Ilker Tunc, Lam C. Tsoi, Elena Stansky, Mehdi Pirooznia, Joanna I Silverman, Marcus Y. Chen, Aditya A. Joshi, Kairong Cui, J. Philip McCoy, Joel M. Gelfand, Erin Stempinski, Charlotte L. Harrington, Martin P. Playford, Heather L. Teague, Andrew Keel, Nehal N. Mehta, Keji Zhao, Pradeep K. Dagur, Carmelo Carmona-Rivera, Justin A. Rodante, Gregory E. Sanda, Nevin J. Varghese, Johann E. Gudjonsson, Youssef A. Elnabawi, Jeffrey S. Berger, Michael S. Garshick, Mariana J. Kaplan, Amit K. Dey, Monica M. Purmalek, Yvonne Baumer, Fayaz Seifuddin
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 1-14 (2019)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • LDGs are a subset of neutrophils that were elevated in psoriasis and associated with the severity of disease. • In psoriasis, LDGs associated with noncalcified coronary plaque burden beyond cardiovascular risk fa
Highlights • LDGs are a subset of neutrophils that were elevated in psoriasis and associated with the severity of disease. • In psoriasis, LDGs associated with noncalcified coronary plaque burden beyond cardiovascular risk fa