Zobrazeno 1 - 10
of 29
pro vyhledávání: '"NES, Nuclear Export Signal"'
Publikováno v:
The Journal of Biological Chemistry
The aryl hydrocarbon receptor (AHR) is a transcription factor activated by exogenous halogenated polycyclic aromatic hydrocarbon compounds, including the environmental toxin TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and naturally occurring dietary a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e2b5476cf6c1e1f9ee2bcbc8cd8049
https://pubmed.ncbi.nlm.nih.gov/34146543
https://pubmed.ncbi.nlm.nih.gov/34146543
Autor:
Lizabeth A. Allison
Publikováno v:
The Journal of Biological Chemistry
A year ago, when I first contemplated writing this article, my intent was to provide a detailed review of the contributions of the diverse community of talented scientists in my lab to the nuclear receptor research field. In the throes of a deadly pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a776d1dd3fdfda25f9f6fc461644083
https://pubmed.ncbi.nlm.nih.gov/33887322
https://pubmed.ncbi.nlm.nih.gov/33887322
Publikováno v:
Kelly, V, Al-Rawi, A, Lewis, D, Kustatscher, G & Ly, T 2022, ' Low cell number proteomic analysis using in-cell protease digests reveals a robust signature for cell cycle state classification ', Molecular and Cellular Proteomics, vol. 21, no. 1, 100169 . https://doi.org/10.1016/j.mcpro.2021.100169
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Comprehensive proteome analysis of rare cell phenotypes remains a significant challenge. We report a method for low cell number MS-based proteomics using protease digestion of mildly formaldehyde-fixed cells in cellulo, which we call the “in-cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9f08dd143b45d961982ffdce6ad432
https://doi.org/10.1016/j.mcpro.2021.100169
https://doi.org/10.1016/j.mcpro.2021.100169
Autor:
Nopporn Chutiwitoonchai, Hironori Sato, Michinori Kakisaka, Takafumi Mano, Osamu Kotani, Yasumitsu Kondoh, Hirotaka Sato, Masaru Yokoyama, Yoko Aida, Hiroyuki Osada
Publikováno v:
Virology
An anti-influenza compound, DP2392-E10 based on inhibition of the nuclear export function of the viral nucleoprotein-nuclear export signal 3 (NP-NES3) domain was successfully identified by our previous high-throughput screening system. Here, we demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a415393a1d052d389fa759f3a5d22458
https://doi.org/10.1016/j.virol.2017.04.001
https://doi.org/10.1016/j.virol.2017.04.001
Publikováno v:
The Journal of Biological Chemistry
The nuclear pore complex is the sole gateway connecting the nucleoplasm and cytoplasm. In humans, the nuclear pore complex is one of the largest multiprotein assemblies in the cell, with a molecular mass of ∼110 MDa and consisting of 8 to 64 copies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9f9983e508bac0c97b5ff5b06fddd2
https://doi.org/10.1016/j.jbc.2021.100856
https://doi.org/10.1016/j.jbc.2021.100856
Autor:
Zhanggui Wang, Xinbing Sui, Liangkun You, Jiansheng Xie, Zhao Jing, Hongsen Li, Jiawei Shou, Hongming Pan, Weidong Han
Publikováno v:
Autophagy
Autophagy is an evolutionarily conserved process in eukaryotes that eliminates harmful components and maintains cellular homeostasis in response to a series of extracellular insults. However, these insults may trigger the downstream signaling of anot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7370b1766f56b7801df377b10de63140
https://doi.org/10.1080/15548627.2015.1017192
https://doi.org/10.1080/15548627.2015.1017192
Autor:
Paolo Pinton, Angela Bononi
Publikováno v:
Methods (San Diego, Calif.)
The tumor suppressor PTEN is a key regulator of a plethora of cellular processes that are crucial in cancer development. Through its lipid phosphatase activity PTEN suppresses the PI3K/AKT pathway to govern cell proliferation, growth, migration, ener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c001a26f52f4eb010d9bdaf2cd08d65
http://europepmc.org/articles/PMC4396696
http://europepmc.org/articles/PMC4396696
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 4, Iss C, Pp 683-688 (2014)
FEBS Open Bio, Vol 4, Iss C, Pp 683-688 (2014)
Highlights • To elucidate vRNP export, we investigated the interactions among Hsc70, M1, and NS2. • Hsc70 interacts with M1 more strongly than with NS2. • Hsc70 competes with NS2 for M1 binding. • These results suggest the involvement of Hsc7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3bdef3f7a27bb3022bc5e94be985939
http://hdl.handle.net/10069/34746
http://hdl.handle.net/10069/34746
Autor:
Sobhkhez, Mehrdad, Skjesol, Astrid, Thomassen, Ernst, Tollersrud, Linn Greiner, Iliev, Dimitar B., Sun, Baojian, Robertsen, Børre, Jørgensen, Jorunn B.
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 858-871 (2014)
FEBS Open Bio
FEBS Open Bio
Highlights • The transcription factors STAT2 and IRF9 from Atlantic salmon have been identified. • STAT2 co-expressed with STAT1 translocates to the nucleus upon IFN stimulation. • STAT2 are tyrosine phosphorylated upon type I IFN and IFNγ sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2fb36a1d7d4dc9ab8df587d745faee17
http://www.sciencedirect.com/science/article/pii/S2211546314000898
http://www.sciencedirect.com/science/article/pii/S2211546314000898
Publikováno v:
Biochemical Journal
The movement of proteins between the cytoplasm and nucleus mediated by the importin superfamily of proteins is essential to many cellular processes, including differentiation and development, and is critical to disease states such as viral disease an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a04fa0789c776f7b2016e8ada9d2062
https://doi.org/10.1042/bj20120150
https://doi.org/10.1042/bj20120150