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L-asparaginases (L-ASNase, EC 3.5.1.1) are amidohydrolases catalysing the conversion of L-Asn to L-Asp and ammonia and to a lower extent L-Gln to L-Glu (L-glutaminase activity, L-GLNase). This enzyme is exploited as an anti-neoplastic agent to treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d4f0554019a06854a65fdc67f548c69
https://doi.org/10.22541/au.166576507.74020437/v1
https://doi.org/10.22541/au.166576507.74020437/v1
Autor:
Sabt A; Chemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Institute, National Research Center, Dokki, Cairo, Egypt., Kitsos S; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Ebaid MS; Department of Chemistry, College of Science, Northern Border University, Arar, Saudi Arabia., Furlan V; Faculty of Chemistry and Chemical Engineering, University of Maribor, Maribor, Slovenia., Pantiora PD; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Tsolka M; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Elkaeed EB; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Diriyah, Saudi Arabia., Hamissa MF; Institute of Organic Chemistry and Biochemistry, Academy of Sciences, Prague, Czech Republic., Angelis N; Section of Animal and Human Physiology, Department of Biology, National and Kapodistrian University of Athens (NKUA), Athens, Greece., Tsitsilonis OE; Section of Animal and Human Physiology, Department of Biology, National and Kapodistrian University of Athens (NKUA), Athens, Greece., Papageorgiou AC; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland., Bren U; Faculty of Chemistry and Chemical Engineering, University of Maribor, Maribor, Slovenia.; Faculty of Mathematics, Natural Sciences and Information Technologies, University of Primorska, Koper, Slovenia.; Institute of Environmental Protection and Sensors, Maribor, Slovenia., Labrou NE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece.
Publikováno v:
PloS one [PLoS One] 2024 Aug 14; Vol. 19 (8), pp. e0306124. Date of Electronic Publication: 2024 Aug 14 (Print Publication: 2024).
Autor:
Tsouri S; Laboratory of Enzyme Technology, Department of Biotechnology, School Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece., Tselo E; Laboratory of Enzyme Technology, Department of Biotechnology, School Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece., Premetis GE; Laboratory of Enzyme Technology, Department of Biotechnology, School Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece., Furlan V; Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia., Pantiora PD; Laboratory of Enzyme Technology, Department of Biotechnology, School Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece., Mavroidi B; Institute of Biosciences & Applications, National Centre for Scientific Research 'Demokritos', 15310 Athens, Greece., Matiadis D; Institute of Biosciences & Applications, National Centre for Scientific Research 'Demokritos', 15310 Athens, Greece.; Department of Biomedical Sciences, University of West Attica, Egaleo Park Campus, 12243 Athens, Greece., Pelecanou M; Institute of Biosciences & Applications, National Centre for Scientific Research 'Demokritos', 15310 Athens, Greece., Papageorgiou AC; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20521 Turku, Finland., Bren U; Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia.; Faculty of Mathematics, Natural Sciences and Information Technologies, University of Primorska, Glagoljaška 8, SI-6000 Koper, Slovenia.; Institute of Environmental Protection and Sensors, Beloruska Ulica 7, SI-2000 Maribor, Slovenia., Sagnou M; Institute of Biosciences & Applications, National Centre for Scientific Research 'Demokritos', 15310 Athens, Greece., Labrou NE; Laboratory of Enzyme Technology, Department of Biotechnology, School Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece.
Publikováno v:
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2024 Mar 11; Vol. 17 (3). Date of Electronic Publication: 2024 Mar 11.
Autor:
Pantiora PD; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855, Athens, Greece., Georgakis ND; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855, Athens, Greece., Premetis GE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855, Athens, Greece., Labrou NE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855, Athens, Greece. lambrou@aua.gr.
Publikováno v:
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2024 Jan 22; Vol. 108 (1), pp. 163. Date of Electronic Publication: 2024 Jan 22.
Autor:
Axarli I; Laboratory of Enzyme Technology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855 Athens, Greece., Ataya F; Department of Biochemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia., Labrou NE; Laboratory of Enzyme Technology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855 Athens, Greece.
Publikováno v:
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2023 Dec 25; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 25.
Autor:
Varotsou C; Laboratory of Enzyme Technology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855 Athens, Greece., Ataya F; Department of Biochemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia., Papageorgiou AC; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20521 Turku, Finland., Labrou NE; Laboratory of Enzyme Technology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855 Athens, Greece.
Publikováno v:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 20; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 20.
Autor:
Mavrommatis A; Laboratory of Nutritional Physiology and Feeding, Department of Animal Science, School of Animal Biosciences, Agricultural University of Athens, 75 Iera Odos Str., GR-11855 Athens, Greece., Tsiplakou E; Laboratory of Nutritional Physiology and Feeding, Department of Animal Science, School of Animal Biosciences, Agricultural University of Athens, 75 Iera Odos Str., GR-11855 Athens, Greece., Zerva A; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Str., GR-11855 Athens, Greece., Pantiora PD; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Str., GR-11855 Athens, Greece., Georgakis ND; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Str., GR-11855 Athens, Greece., Tsintzou GP; Laboratory of Molecular Biology of Plants, School of Agricultural Sciences, University of Thessaly, GR-38221 Volos, Greece., Madesis P; Laboratory of Molecular Biology of Plants, School of Agricultural Sciences, University of Thessaly, GR-38221 Volos, Greece.; Institute of Applied Biosciences, CERTH, 6th km Charilaou-Thermis Road, P.O. Box 361, Thermi, GR-57001 Thessaloniki, Greece., Labrou NE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Str., GR-11855 Athens, Greece.
Publikováno v:
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2023 Oct 19; Vol. 12 (10). Date of Electronic Publication: 2023 Oct 19.
Autor:
Premetis GE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855 -Athens, Greece., Georgakis ND; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855 -Athens, Greece., Stathi A; Department of Microbiology, 'Aghia Sophia' Children's Hospital, 11527 Athens, Greece., Labrou NE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, GR-11855 -Athens, Greece. Electronic address: Lambrou@aua.gr.
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2023 Jul 01; Vol. 1871 (4), pp. 140918. Date of Electronic Publication: 2023 May 05.
Autor:
Varotsou C; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece., Premetis GE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece., Labrou NE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece.
Publikováno v:
International journal of molecular sciences [Int J Mol Sci] 2023 May 10; Vol. 24 (10). Date of Electronic Publication: 2023 May 10.
Autor:
Premetis GE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855, Athens, Greece., Stathi A; Department of Microbiology, 'Aghia Sophia' Children's Hospital, 11527, Athens, Greece., Papageorgiou AC; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20521, Turku, Finland., Labrou NE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855, Athens, Greece. Lambrou@aua.gr.
Publikováno v:
Scientific reports [Sci Rep] 2023 May 08; Vol. 13 (1), pp. 7450. Date of Electronic Publication: 2023 May 08.