Tribbles 2 pseudokinase confers enzalutamide resistance in prostate cancer by promoting lineage plasticity

Autor: Jitender Monga, Indra Adrianto, Craig Rogers, Shirish Gadgeel, Dhananjay Chitale, Joshi J. Alumkal, Himisha Beltran, Amina Zoubeidi, Jagadananda Ghosh

Publikováno v: The Journal of Biological Chemistry

Enzalutamide, a second-generation antiandrogen, is commonly prescribed for the therapy of advanced prostate cancer, but enzalutamide-resistant, lethal, or incurable disease invariably develops. To understand the molecular mechanism(s) behind enzaluta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8bb1662a1499b7161cd3cc524395ab
http://europepmc.org/articles/PMC8800106

Corrigendum to ‘Roles of alternative RNA splicing of the Bif-1 gene by SRRM4 during the development of treatment-induced neuroendocrine prostate cancer’. [EBioMedicine 31 (2018) 267–275>

Autor: Yinan Li, Yuxin Tang, Ning Xie, Jessica M. Lovnicki, Jiaoti Huang, Ahn R. Lee, Xuesen Dong, Xiang Chen, Zhi Long, Yu Gan

Publikováno v: EBioMedicine
EBioMedicine, Vol 54, Iss, Pp-(2020)

Treatment-induced neuroendocrine prostate cancer (t-NEPC) is an aggressive subtype of prostate cancer (PCa) that becomes more prevalent when hormonal therapy, chemotherapy, or radiation therapy is applied to patients with metastatic prostate adenocar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9182b62ef89de9c5ce14e30ae1f8490b
https://doi.org/10.1016/j.ebiom.2020.102741

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Reprogramming landscape highlighted by dynamic transcriptomes in therapy-induced neuroendocrine differentiation.

Autor: Asberry AM; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA., Liu S; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana University Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA., Nam HS; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA., Deng X; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA., Wan J; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana University Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA., Hu CD; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.; Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN, USA.

Publikováno v: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2022 Oct 27; Vol. 20, pp. 5873-5885. Date of Electronic Publication: 2022 Oct 27 (Print Publication: 2022).

Gross Findings of Widespread Visceral Metastasis of Prostatic Adenocarcinoma With Neuroendocrine Features: A Case Report.

Autor: Habibian DJ; Department of Urology, Winthrop University Hospital, Mineola, New York, USA., Dao AE; Department of Urology, Winthrop University Hospital, Mineola, New York, USA., Kumar S; Department of Pathology, Winthrop University Hospital, Mineola, New York, USA., Schiff J; Department of Urology, Winthrop University Hospital, Mineola, New York, USA., Kosinski KE; Department of Urology, Winthrop University Hospital, Mineola, New York, USA., Katz AE; Department of Urology, Winthrop University Hospital, Mineola, New York, USA.

Publikováno v: Urology case reports [Urol Case Rep] 2016 Jul 21; Vol. 8, pp. 49-51. Date of Electronic Publication: 2016 Jul 21 (Print Publication: 2016).