Poloxamer-chitosan-based Naringenin nanoformulation used in brain targeting for the treatment of cerebral ischemia

Autor: Aftab Alam, Abuzer Ali, Mohd Amir, Farhan Jalees Ahmad, Wasim Ahmad, Niyaz Ahmad, Rizwan Ahmad

Publikováno v: Saudi Journal of Biological Sciences, Vol 27, Iss 1, Pp 500-517 (2020)
Saudi Journal of Biological Sciences

Graphical abstract
Objective Here, the aim is to improve the bioavailability of Naringenin (NRG) in brain and to establish the highest remedial benefit from a novel anti-ischemic medicine i.e. NRG. Methods A novel Naringenin-loaded-nanoemulsion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbf9305501d6bea3502fb47e997e300
http://www.sciencedirect.com/science/article/pii/S1319562X19302402

Nanotechnological strategies for systemic microbial infections treatment: A review

Autor: Giovanna Capaldi Fortunato, Taís Maria Bauab, Karen Cristina dos Santos, Marlus Chorilli, Camila Fernanda Rodero, Luciani Gaspar de Toledo, Gabriel Davi Marena, Patrícia Bento da Silva, Matheus Aparecido dos Santos Ramos, Bruna Almeida Furquim de Camargo

Publikováno v: International Journal of Pharmaceutics

Graphical abstract
Systemic infections is one of the major causes of mortality worldwide, and a shortage of drug approaches applied for the rapid and necessary treatment contribute to increase the levels of death in affected patients. Several dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0264a079746e44cffe64f163a38fc24
https://doi.org/10.1016/j.ijpharm.2020.119780

Immunomodulation of TH2 biased immunity with mucosal administration of nanoemulsion adjuvant

Autor: Anna U. Bielinska, Jessica J. O’Konek, James R. Baker, Katarzyna W. Janczak

Publikováno v: Vaccine

Highlights • Nanoemulsion vaccine adjuvant induces robust antigen specific TH1-biased immunity. • Nanoemulsion vaccine adjuvant suppresses established TH2 immunity. • Efficacy of nanoemulsion vaccine in mice with pre-existing immunity to same a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4741d8dced5ae148a450e5dd326bbad0

Precise delivery of obeticholic acid via nanoapproach for triggering natural killer T cell-mediated liver cancer immunotherapy.

Autor: Ji G; Department of Gastrointestinal and Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China.; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China., Ma L; Department of Gastrointestinal and Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China., Yao H; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.; Key Laboratory of Zoonosis, Chinese Ministry of Education, College of Basic Medical Science, Jilin University, Changchun 130021, China., Ma S; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.; Jilin Biomedical Polymers Engineering Laboratory, Changchun 130022, China., Si X; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China., Wang Y; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.; Second Hospital of Shandong University, Jinan 250000, China., Bao X; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.; Second Hospital of Jilin University, Changchun 130041, China., Ma L; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.; Jilin Biomedical Polymers Engineering Laboratory, Changchun 130022, China., Chen F; Department of Gastrointestinal and Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China.; State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, China., Ma C; Department of Gastrointestinal and Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China., Huang L; Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Fang X; Department of Gastrointestinal and Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China.; State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, China., Song W; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.; Jilin Biomedical Polymers Engineering Laboratory, Changchun 130022, China.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Nov; Vol. 10 (11), pp. 2171-2182. Date of Electronic Publication: 2020 Sep 15.

Poloxamer-chitosan-based Naringenin nanoformulation used in brain targeting for the treatment of cerebral ischemia.

Autor: Ahmad N; Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.; Department of Pharmaceutical Chemistry, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Ahmad R; Department of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Ahmad FJ; Nanomedicine Lab, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, Hamdard Nagar, New Delhi, India., Ahmad W; Department of Pharmacy, Mohammad Al-Mana College for Medical Sciences, Safaa, Dammam-34222, Saudi Arabia., Alam MA; Department of Pharmaceutics, School of Medical and Allied Sciences, Galgotias University, Gautam Budh Nagar, Greater Noida 201310, India., Amir M; Department of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Ali A; College of Pharmacy, Taif University, Taif 21974, Saudi Arabia.

Publikováno v: Saudi journal of biological sciences [Saudi J Biol Sci] 2020 Jan; Vol. 27 (1), pp. 500-517. Date of Electronic Publication: 2019 Nov 22.