Zobrazeno 1 - 10
of 35
pro vyhledávání: '"ND, normal diet"'
Autor:
Tetsuo Takehara, Tomohide Tatsumi, Ryotaro Sakamori, Kumiko Shirai, Sadatsugu Sakane, Yuki Makino, Kenji Fukumoto, Takahiro Kodama, Yuta Myojin, Hayato Hikita, Youichi Sasaki, Ryoko Yamada, Yuki Tahata, Naoki Mizutani, Shinnosuke Kudo
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1683-1699 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Although nonalcoholic fatty liver disease (NAFLD) is closely associated with obesity, the role of adipose tissue in NAFLD is not well-understood. Because autophagy has been reported to be involved in the degradation of lipid droplet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1011f70ab32424b90b7306ec81dc0f77
https://doi.org/10.1016/j.jcmgh.2021.07.008
https://doi.org/10.1016/j.jcmgh.2021.07.008
Publikováno v:
Journal of Advanced Research, Vol 26, Iss, Pp 123-135 (2020)
Journal of Advanced Research
Journal of Advanced Research
Graphical abstract The map illustrating mechanisms associated with lncRNA HIF1A-AS2-mediated inflammation in the atherosclerosis. LncRNA HIF1A-AS2 forms a complex with USF1, which is recruited into the ATF2 promoter to elevate ATF2 expression, thus p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47972e7d0a5a67e00cdb998231298698
http://www.sciencedirect.com/science/article/pii/S2090123220301740
http://www.sciencedirect.com/science/article/pii/S2090123220301740
Autor:
Justine Gillard, Laure-Alix Clerbaux, Bart Staels, Anne Tailleux, Isabelle Leclercq, Laure B. Bindels, Maxime Nachit, Christine Sempoux
Publikováno v:
JHEP reports, vol. 4, no. 1, pp. 100387
JHEP Reports, Vol 4, Iss 1, Pp 100387-(2022)
JHEP reports, Vol. 4, no.1, p. 100387 [1-13] (2022)
JHEP Reports
JHEP Reports, Vol 4, Iss 1, Pp 100387-(2022)
JHEP reports, Vol. 4, no.1, p. 100387 [1-13] (2022)
JHEP Reports
Background & Aims Through FXR and TGR5 signaling, bile acids (BAs) modulate lipid and glucose metabolism, inflammation and fibrosis. Hence, BAs returning to the liver after enteric secretion, modification and reabsorption may contribute to the pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f803f3cd8976e73d533d8b1885ead5
https://serval.unil.ch/notice/serval:BIB_8BED7E41CA16
https://serval.unil.ch/notice/serval:BIB_8BED7E41CA16
Autor:
Nuria Pell, Marcos Fernandez-Alfara, Andre Franke, Karl P. Rheinwalt, Malte C. Rühlemann, Salvador Naranjo-Suarez, Clara Suñer, Alexandra Balvey, Raúl Méndez, Jonel Trebicka, Mercedes Fernandez, Julia Carbo, Corinna Bang, Louise B. Thingholm, Oscar Reina, Ester Garcia-Pras, Javier Gallego, Marta Ramirez-Pedraza, Veronica Chanes, Robert Schierwagen
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 54, Iss, Pp 101388-(2021)
Molecular Metabolism, Vol 54, Iss, Pp 101388-(2021)
Objective Obesity represents a growing health problem that is reaching pandemic dimensions and lacks effective cures, thus highlighting an urgent need for better mechanistic understanding and new therapeutic strategies. Unlike transcription, the func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ae7e360f96f5ac2a1a8c0ec2bedd48
http://europepmc.org/articles/PMC8711066
http://europepmc.org/articles/PMC8711066
Autor:
Yuki Matsushita, Hiroto Kinoshita, Keisuke Tateishi, Masahiro Hata, Nobumi Suzuki, Koji Uchino, Kazuhiko Koike, Hayato Nakagawa, Satoshi Kawamura, Yoshihiro Hirata, Tomoharu Yamada, Yuki Hayata, Mayo Tsuboi, Yoku Hayakawa, Takuma Nakatsuka, Shigeyuki Kurosaki, Yasuo Tanaka
Publikováno v:
JHEP Reports, Vol 3, Iss 4, Pp 100315-(2021)
JHEP Reports
JHEP Reports
Background & Aims Liver lobules are typically subdivided into 3 metabolic zones: zones 1, 2, and 3. However, the contribution of zonal differences in hepatocytes to liver regeneration, as well as to carcinogenic susceptibility, remains unclear. Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf48b03f7d575d64288fadbe4f171fb
http://www.sciencedirect.com/science/article/pii/S2589555921000914
http://www.sciencedirect.com/science/article/pii/S2589555921000914
Autor:
Jeremy D. Semrau, Roman S. Polishchuk, Andreas E. Kremer, Bipin S. Baral, Claudia Einer, Christine von Toerne, Gerald Denk, Hans Zischka, Sabine Borchard, Tamara Rieder, Josef Lichtmannegger, Karl Heinz Weiss, Stefanie M. Hauck, Alan A. DiSpirito, Jennifer-Christin Müller, Uwe Karst, Elena V. Polishchuk, Carola Eberhagen, Ralf Wimmer, Christin Leitzinger, Frauke Neff, Simon Hohenester, Bastian Popper
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 3, Pp 571-596 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cell. Mol. Gast. Hept. 7, 571-596 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cell. Mol. Gast. Hept. 7, 571-596 (2019)
Background & Aims In Wilson disease, ATP7B mutations impair copper excretion into bile. Hepatic copper accumulation may induce mild to moderate chronic liver damage or even acute liver failure. Etiologic factors for this heterogeneous phenotype remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0127ca524307588532a6af17ccfa54
http://www.sciencedirect.com/science/article/pii/S2352345X18301802
http://www.sciencedirect.com/science/article/pii/S2352345X18301802
Autor:
Masanobu Morita, Yu Yamaguchi, Fumitoshi Irie, Yu Mei, Ai Shimane, Kazuhiko Yanai, Takeo Yoshikawa, Rina Otsuka, Takuro Matsuzawa
Publikováno v:
The Journal of Biological Chemistry
Heparan sulfate (HS), a highly sulfated linear polysaccharide, is involved in diverse biological functions in various tissues. Although previous studies have suggested a possible contribution of HS to the differentiation of white adipocytes, there ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96a1800166fbc18d437ce1e6f65a7f4
https://pubmed.ncbi.nlm.nih.gov/34310946
https://pubmed.ncbi.nlm.nih.gov/34310946
Autor:
Bidault-Jourdainne, Valeska, Merlen, Grégory, Glénisson, Mathilde, Doignon, Isabelle, Garcin, Isabelle, Péan, Noémie, Boisgard, Raphaël, Ursic-Bedoya, José, Serino, Matteo, Ullmer, Christoph, Humbert, Lydie, Abdelrafee, Ahmed, Golse, Nicolas, Vibert, Eric, Duclos-Vallée, Jean-Charles, Rainteau, Dominique, Tordjmann, Thierry
Publikováno v:
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100214. ⟨10.1016/j.jhepr.2020.100214⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100214. ⟨10.1016/j.jhepr.2020.100214⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100214-(2021)
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100214. ⟨10.1016/j.jhepr.2020.100214⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100214. ⟨10.1016/j.jhepr.2020.100214⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100214-(2021)
Background & Aims As the composition of the bile acid (BA) pool has a major impact on liver pathophysiology, we studied its regulation by the BA receptor Takeda G protein coupled receptor (TGR5), which promotes hepatoprotection against BA overload. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bd93ad251fbdc56587d850b8c657ea9c
https://hal.sorbonne-universite.fr/hal-03148612
https://hal.sorbonne-universite.fr/hal-03148612
Autor:
Devyani Agarwal, Leila Eter, Kanakadurga Singer, Mita Varghese, Ravi Patel, Simin Abrishami, Maria Westerhoff, Perla Subbaiah, Jeremy Clemente, Cameron Griffin, Mohammed N. Islam, Layla Hak, Nicholas Lanzetta, Emily Bowers, Arianna Lerner
Publikováno v:
The Journal of Biological Chemistry
Men have a statistically higher risk of metabolic and cardiovascular disease than premenopausal women, but the mechanisms mediating these differences are elusive. Chronic inflammation during obesity contributes to disease risk and is significantly mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f224bd4472a9c78aae25e99d558471df
https://doi.org/10.1016/j.jbc.2021.101229
https://doi.org/10.1016/j.jbc.2021.101229
Autor:
Xin Tong, Lei Yin, Ram K. Menon, Colin L. Stewart, Min-Jung Park, Makayla J. Brunt, M. Bishr Omary, Raymond Kwan, Maria Brzozowski, Graham F. Brady, Sujith V.W. Weerasinghe, Hope Martin
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 3, Pp 365-383 (2017)
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 3, Pp 365-383 (2017)
Background & Aims Lamins are nuclear intermediate filament proteins that comprise the major components of the nuclear lamina. Mutations in LMNA, which encodes lamins A/C, cause laminopathies, including lipodystrophy, cardiomyopathy, and premature agi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60446073e37b69f0d71e80d0e0991cc
https://doi.org/10.1016/j.jcmgh.2017.06.005
https://doi.org/10.1016/j.jcmgh.2017.06.005