Piperine analog PGP-41 treatment overcomes paclitaxel resistance in NCI/ADR-RES ovarian cells by inhibition of MDR1

Autor: Sharma, Sadhana ^{a, b}, Choudhary, Sushil ^{a, b}, Kaur, Sukhleen ^{a, b}, Reddy, M. Venkat ^c, Thota, Niranjan ^{c, d}, Singh, Amarinder ^a, Koul, Surrinder ^c, Khan, Inshad Ali ^e, Ahmed, Zabeer ^{a, b, ∗∗}, Kumar, Ajay ^{a, b, ∗}

Publikováno v: In Chemico-Biological Interactions 25 August 2023 381

Modulation of selenium-dependent glutathione peroxidase activity enhances doxorubicin-induced apoptosis, tumour cell killing and hydroxyl radical production in human NCI/ADR-RES cancer cells despite high-level P-glycoprotein expression

Autor: James H. Doroshow, Agnes Juhasz

Publikováno v: Free Radic Res

To define the role of glutathione peroxidase (GPx) in modulating the oxygen radical-related cytotoxicity of doxorubicin and H(2)O(2) in cells that overexpress P-glycoprotein (Pgp), the GPx activity of NCI/ADR-RES cancer cells was altered by growth in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e1710b62a91c3cf1c5824fe102f4ae
https://doi.org/10.1080/10715762.2019.1641602

Evolutionary dynamics of cancer multidrug resistance in response to olaparib and photodynamic therapy

Autor: Yan Baglo, Aaron J. Sorrin, Cindy Liu, Jocelyn Reader, Dana M. Roque, Huang-Chiao Huang, Xiaocong Pu

Publikováno v: Translational Oncology
Translational Oncology, Vol 14, Iss 11, Pp 101198-(2021)

Highlights • Combination of olaparib and photodynamic therapy is effective in reducing the number and clonogenic survival of ovarian cancer cells. • Photodynamic therapy using a lipidated photosensitizer reduces the selective advantage of olapari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866ca31ee986ff0e2b20595aac813dc6
https://doi.org/10.1016/j.tranon.2021.101198

Transcriptional profiling of NCI/ADR-RES cells unveils a complex network of signaling pathways and molecular mechanisms of drug resistance

Autor: Jessica Castro, Anna Vert, Marc Ribó, Antoni Benito, Maria Vilanova

Publikováno v: OncoTargets and therapy
OncoTargets and Therapy, 2018, vol. 11, p. 221-237
Articles publicats (D-B)
DUGiDocs – Universitat de Girona
instname
Recercat. Dipósit de la Recerca de Catalunya

Anna Vert1,2 Jessica Castro,1,2 Marc Ribó,1,2 Maria Vilanova,1,2 Antoni Benito1,2 1Protein Engineering Laboratory, Department of Biology, Faculty of Sciences, Universitat de Girona, 2Biomedical Research Institute of Girona (IDIBGi), Girona, Spain Ba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c151c20f35c04e6d80d19be2bf399ede
http://europepmc.org/articles/PMC5757493

Decursin inAngelica gigasNakai (AGN) Enhances Doxorubicin Chemosensitivity in NCI/ADR-RES Ovarian Cancer Cells via Inhibition of P-glycoprotein Expression

Autor: Sung-Gook Cho, Min-Soo Kim, Ilhwan Kim, Hyeong Sim Choi, Seong-Gyu Ko, Seung Hee Moon, Min Kyoung Kim

Publikováno v: Phytotherapy Research. 30:2020-2026

Angelica gigas Nakai (AGN, Korean Dang-gui) is traditionally used for the treatment of various diseases including cancer. Here, we investigated multidrug-resistant phenotype-reversal activities of AGN and its compounds (decursin, ferulic acid, and no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd4b1dec044acec66b5a7d59a788a726
https://doi.org/10.1002/ptr.5708