In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole

Autor: Thilo Faber, Yann Pellequer, Marius Monschke, Alf Lamprecht, Karl G. Wagner, Anna K. Krome, Rafael D. Bachmaier, Edmont Stoyanov

Publikováno v: International Journal of Pharmaceutics: X, Vol 3, Iss, Pp 100076-(2021)
International Journal of Pharmaceutics: X

Using polymers as additives to formulate ternary amorphous solid dispersions (ASDs) has successfully been established to increase the bioavailability of poorly soluble drugs, when one polymer is not able to provide both, stabilizing the drug in the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7165733c3f1d02f1297718b7b99d0e1
https://doi.org/10.1016/j.ijpx.2021.100076

Pharmacokinetic aspects and in vitro-in vivo correlation potential for lipid-based formulations

Autor: Sivacharan Kollipara, Rajesh Kumar Gandhi

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 4, Iss 5, Pp 333-349 (2014)

Lipid-based formulations have been an attractive choice among novel drug delivery systems for enhancing the solubility and bioavailability of poorly soluble drugs due to their ability to keep the drug in solubilized state in the gastrointestinal trac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8801d2e3ffa86c6c9aa9536be6180bb
https://pubmed.ncbi.nlm.nih.gov/26579403

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In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole.

Autor: Bachmaier RD; Department of Pharmaceutical Technology and Biopharmaceutics, University of Bonn, 53121 Bonn, Germany., Monschke M; Department of Pharmaceutical Technology and Biopharmaceutics, University of Bonn, 53121 Bonn, Germany., Faber T; Department of Pharmaceutical Technology and Biopharmaceutics, University of Bonn, 53121 Bonn, Germany., Krome AK; Department of Pharmaceutical Technology and Biopharmaceutics, University of Bonn, 53121 Bonn, Germany., Pellequer Y; UFR Santé, Laboratoire de Pharmacie Galénique, 19, rue Ambroise Paré, 25000 Besancon, France., Stoyanov E; Nisso Chemical Europe GmbH, Berliner Allee 42, 40212 Düsseldorf, Germany., Lamprecht A; Department of Pharmaceutical Technology and Biopharmaceutics, University of Bonn, 53121 Bonn, Germany.; UFR Santé, Laboratoire de Pharmacie Galénique, 19, rue Ambroise Paré, 25000 Besancon, France., Wagner KG; Department of Pharmaceutical Technology and Biopharmaceutics, University of Bonn, 53121 Bonn, Germany.

Publikováno v: International journal of pharmaceutics: X [Int J Pharm X] 2021 Mar 17; Vol. 3, pp. 100076. Date of Electronic Publication: 2021 Mar 17 (Print Publication: 2021).