Zobrazeno 1 - 10
of 14
pro vyhledávání: '"NCBES"'
Autor:
Fitzgibbon, Marie
Interferon-α (IFN-α) is a pro-inflammatory cytokine used for the treatment of hepatitis B and C as well as various malignancies. However, therapy is often associated with neuropsychiatric side effects, including depression and anxiety (Schaefer et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::41c2a8fd030b9c53848ca63d0065d12e
http://hdl.handle.net/10379/5358
http://hdl.handle.net/10379/5358
Autor:
Jennings, Elaine
Pain represents a major unmet clinical need and affects a large number of individuals worldwide. Numerous studies indicate a very high prevalence of chronic pain comorbid with psychiatric disorders such as anxiety and depression. Mounting evidence su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::39e67b4b7faee27fa4b7a0db6eff58a5
http://hdl.handle.net/10379/5435
http://hdl.handle.net/10379/5435
Autor:
Lowe, Shane Alan
Functional ability describes a person's capability to perform those tasks that are necessary to live independently. It is a proven predictor of functional decline, the need for hospitalisation and institutionalisation and for morbidity and mortality.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::150dc8038c82fe945f140e96e85e6f70
http://hdl.handle.net/10379/4271
http://hdl.handle.net/10379/4271
Autor:
Rui, Yu
Over the past two decades, cancer research has produced tremendous advances in our understanding of the pathogenesis of cancer. Among the most important of these advances is the realization that apoptosis and the proteins involved in this process of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::6d85365f9dfe6d46bad5df9ff3600a29
http://hdl.handle.net/10379/3519
http://hdl.handle.net/10379/3519
Autor:
Ní Fhlathartaigh, Mary
Endoplasmic reticulum (ER) stress is a homeostatic signalling pathway, linked to many neurological diseases including multiple sclerosis (MS), which can lead to cell death when prolonged. Increasing evidence suggests that Calreticulin (CRT), a multif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::fadb3a9a44dab2e74d9e44f2d9ac89a2
http://hdl.handle.net/10379/3568
http://hdl.handle.net/10379/3568
Autor:
Duffy, Michelle M.
T-helper 17 (Th17) cells play a pathogenic role in multiple sclerosis, inflammatory bowel disease, psoriasis, acute kidney injury, glomerulonephritis and transplant rejection. Mesenchymal stem cells (MSCs) are immunosuppressive with potential to trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::0956198ab6bfcc7cb55a60eb1d06fa6b
http://hdl.handle.net/10379/3592
http://hdl.handle.net/10379/3592
Autor:
Alexander, Jennifer
A complete spatiotemporal profile of the mechanisms involved in the synthesis, processing, and transport of RNA will improve our understanding of cell function and behaviour under various biological cues, which could potentially advance the field of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::38209e939ca89fd0628301c3010ec365
http://hdl.handle.net/10379/3272
http://hdl.handle.net/10379/3272
Autor:
Wilk, Mieszko
Cornea transplantation (penetrating keratoplasty) is the most frequent form of allograft transplantation in humans with a 90 % success rate in the first 2 years, however, the rate of survival decreases over time and drops to approximately 62% after 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::854f41d78f95a053e1072cc02523a699
http://hdl.handle.net/10379/4971
http://hdl.handle.net/10379/4971
Background Dot1L, a histone methyltransferase that targets histone H3 lysine 79 (H3K79), has been implicated in gene regulation and the DNA damage response although its functions in these processes remain poorly defined. Methodology/Principal Finding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::aff855de10ff147c9ad9939c3db94eb5
http://hdl.handle.net/10379/1936
http://hdl.handle.net/10379/1936
Adult mesenchymal stem cells (MSCs) are non-hematopoietic cells with multi-lineage potential to differentiate into various tissues of mesodermal origin. They can be isolated from bone marrow and other tissues and have the capacity to extensively prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1513::8008fcf4a0b9dac9f2923e304204ec41
http://hdl.handle.net/10379/1126
http://hdl.handle.net/10379/1126