Zobrazeno 1 - 9
of 9
pro vyhledávání: '"NC, Normal chow"'
Autor:
N. Thao N. Galvan, Mercedes Barzi, John A. Goss, William R. Lagor, David D. Moore, Adam Dean, Neil J. McKenna, Pavel Sumazin, Barry Zorman, Diane Yang, Beatrice Bissig-Choisat, Karl-Dimiter Bissig, Xavier Legras, David E. Cohen, Robert Brian York, Malgorzata Borowiak, Michele Alves-Bezerra, Scott A. Ochsner
Publikováno v:
JHEP reports : innovation in hepatology, vol 3, iss 3
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100281-(2021)
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100281-(2021)
Background & Aims The accumulation of neutral lipids within hepatocytes underlies non-alcoholic fatty liver disease (NAFLD), which affects a quarter of the world’s population and is associated with hepatitis, cirrhosis, and hepatocellular carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b0393a5555874a5526c491b8421dfd
https://escholarship.org/uc/item/2hg8h2x9
https://escholarship.org/uc/item/2hg8h2x9
Autor:
Shaoping Guan, Xinping Liu, Richard W. Gross, Harold F. Sims, Beverly Gibson Dilthey, Sung Ho Moon
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100052-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100052-(2021)
High-fat (HF) diet–induced obesity precipitates multiple metabolic disorders including insulin resistance, glucose intolerance, oxidative stress, and inflammation, resulting in the initiation of cell death programs. Previously, we demonstrated muri
Autor:
Mizuko Osaka, Michiyo Deushi, Masayuki Yoshida, Jiro Aoyama, Akihito Ishigami, Tomoko Funakoshi
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Neutrophil adhesion to the vascular endothelium in the femoral artery of low-density lipoprotein receptor–null mice fed with HFD was significantly enhanced compared with wild-type mice fed with HFD or low-density
Highlights • Neutrophil adhesion to the vascular endothelium in the femoral artery of low-density lipoprotein receptor–null mice fed with HFD was significantly enhanced compared with wild-type mice fed with HFD or low-density
Autor:
Frédéric Lopez, Céline Pomié, Anthony Puel, Vincent Blasco-Baque, Lucile Garidou, Philippe Valet, Michael Courtney, Rémy Burcelin, Aurélie Waget, Jacques Amar, Vincent Azalbert, Benjamin Lelouvier, Florence Servant, Pascale Klopp, Simon Nicolas, Cédric Dray, Pascale Loubieres
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 5, Iss 6, Pp 392-403 (2016)
Molecular Metabolism, Vol 5, Iss 6, Pp 392-403 (2016)
Objective To demonstrate that glycemia and insulin resistance are controlled by a mechanism involving the adaptive immune system and gut microbiota crosstalk. Methods We triggered the immune system with microbial extracts specifically from the intest
Autor:
Osaka M; Department of Life Science and Bioethics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.; Department of Nutrition and Metabolism in Cardiovascular Disease, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Deushi M; Department of Life Science and Bioethics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Aoyama J; Department of Life Science and Bioethics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.; Department of Neurosurgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Funakoshi T; Research Team for Functional Biogerontology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.; Department of Physiology, Juntendo University Graduate School of Medicine, Tokyo, Japan., Ishigami A; Research Team for Functional Biogerontology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan., Yoshida M; Department of Life Science and Bioethics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Publikováno v:
JACC. Basic to translational science [JACC Basic Transl Sci] 2021 May 19; Vol. 6 (6), pp. 507-523. Date of Electronic Publication: 2021 May 19 (Print Publication: 2021).
Autor:
Bissig-Choisat B; Department of Pediatrics, Division of Medical Genetics, Duke University, Durham, NC, USA., Alves-Bezerra M; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA., Zorman B; Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Ochsner SA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Barzi M; Department of Pediatrics, Division of Medical Genetics, Duke University, Durham, NC, USA., Legras X; Department of Pediatrics, Division of Medical Genetics, Duke University, Durham, NC, USA., Yang D; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Borowiak M; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.; Institute for Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz Universtiy, Poznan, Poland., Dean AM; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., York RB; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Galvan NTN; Department of Surgery, Texas Children's Hospital, Houston, TX, USA., Goss J; Department of Surgery, Texas Children's Hospital, Houston, TX, USA., Lagor WR; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA., Moore DD; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Cohen DE; Joan & Sanford I. Weill Department of Medicine, Weill Cornell Medical College, New York, NY, USA., McKenna NJ; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Sumazin P; Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Bissig KD; Department of Pediatrics, Division of Medical Genetics, Duke University, Durham, NC, USA.; Y.T. and Alice Chen Pediatric Genetics and Genomics Research Center, Duke University, Durham, NC, USA.; Division of Gastroenterology, Department of Medicine, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.; Duke Cancer Institute, Duke University, Durham, NC, USA.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2021 Mar 21; Vol. 3 (3), pp. 100281. Date of Electronic Publication: 2021 Mar 21 (Print Publication: 2021).
Autor:
Pomié C; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Blasco-Baque V; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Klopp P; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Nicolas S; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Waget A; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Loubières P; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Azalbert V; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Puel A; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Lopez F; Groupe Protéomique Centre Recherche Cancer Toulouse, Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1037, 2 avenue Hubert Curien, CS 53717, 31037 Toulouse Cedex 1, France., Dray C; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 3: « Adipokines, obesity and associated Pathologies », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Valet P; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 3: « Adipokines, obesity and associated Pathologies », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Lelouvier B; VAIOMER SAS, 516 Rue Pierre et Marie Curie, 31670 Labège, France., Servant F; VAIOMER SAS, 516 Rue Pierre et Marie Curie, 31670 Labège, France., Courtney M; VAIOMER SAS, 516 Rue Pierre et Marie Curie, 31670 Labège, France., Amar J; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France., Burcelin R; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France. Electronic address: remy.burcelin@inserm.fr., Garidou L; Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France; Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Team 2: « Intestinal Risk Factors, Diabetes, Dyslipidemia », 1 avenue Jean Poulhès, BP 84225, F-31432 Toulouse Cedex 4, France. Electronic address: lucile.garidou@gmail.com.
Publikováno v:
Molecular metabolism [Mol Metab] 2016 Mar 28; Vol. 5 (6), pp. 392-403. Date of Electronic Publication: 2016 Mar 28 (Print Publication: 2016).
Autor:
Nakatsuji H; Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan., Kishida K; Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan., Sekimoto R; Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan., Funahashi T; Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan ; Department of Metabolism and Atherosclerosis, Graduate School of Medicine, Osaka University, Osaka, Japan., Shimomura I; Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.
Publikováno v:
FEBS open bio [FEBS Open Bio] 2014 Mar 12; Vol. 4, pp. 276-82. Date of Electronic Publication: 2014 Mar 12 (Print Publication: 2014).
Autor:
Patterson CM; Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48105, USA., Villanueva EC, Greenwald-Yarnell M, Rajala M, Gonzalez IE, Saini N, Jones J, Myers MG Jr
Publikováno v:
Molecular metabolism [Mol Metab] 2012 Jul 26; Vol. 1 (1-2), pp. 61-9. Date of Electronic Publication: 2012 Jul 26 (Print Publication: 2012).