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Modulation of Septo-Hippocampal Neural Responses in Anesthetized and Behaving Rats by Septal AMPA Receptor Mechanisms

Autor: Khairunisa Mohamad Ibrahim, Mohammed Zacky Ariffin, Sanjay Khanna

Publikováno v: Frontiers in Neural Circuits, Vol 15 (2021)

This study explored the effects of septal glutamatergic transmission on septal-hippocampal theta activity via intraseptal microinjection of antagonist at AMPA receptors (AMPAR). The current results showed that microinjection of AMPAR antagonist, NBQX

Externí odkaz: https://doaj.org/article/713db8f439584d46b36cbd5d06384f45

Antidepressant‐like effect of low dose of scopolamine in the H/Rouen genetic mouse model of depression

Autor: Stéphane Jamain, Malika El Yacoubi, Jean-Marie Vaugeois

Publikováno v: Fundamental & Clinical Pharmacology
Fundamental & Clinical Pharmacology, Wiley, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, Wiley, 2021, 35 (4), pp.645-649. ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 2021, 35 (4), pp.645-649. ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology, Wiley, 2020, ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology, Wiley, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, Wiley, 2020, ⟨10.1111/fcp.12639⟩

International audience; Rodent models of depression are useful for the investigation of cellular and neuronal mechanisms of antidepressant drugs and for the discovery of potential new targets. In this study, we examined the antidepressant-like effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611d863b7d985134ce6fae02ac9ac9ac
https://doi.org/10.1111/fcp.12639

Involvement of Hippocampal AMPA Receptors in Electroacupuncture Attenuating Depressive-Like Behaviors and Regulating Synaptic Proteins in Rats Subjected to Chronic Unpredictable Mild Stress

Autor: Li Jiang, Junhe Zhou, Le Luo, Nenggui Xu, Wei Yi, Peidong Huang, Hao Zhang, Xiaorong Tang, Jianhua Liu, Wenbin Fu

Publikováno v: World Neurosurgery. 139:e455-e462

Objective A large body of evidence has suggested that the disruptions of neural plasticity in the brain play a pivotal role in major depressive disorder (MDD). Electroacupuncture (EA) therapy has been shown to be an effective treatment modality for M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1f90ae41d644d7dbbca53f3d19f6e2
https://doi.org/10.1016/j.wneu.2020.04.042

Co-administration of cannabidiol and ketamine induces antidepressant-like effects devoid of hyperlocomotor side-effects

Autor: P.H. Gobira, Gregers Wegener, Ariandra G. Sartim, J. Marques, K.M. Silveira, Sâmia R.L. Joca, Francisco Silveira Guimarães

Publikováno v: Sartim, A G, Marques, J, Silveira, K M, Gobira, P H, Guimarães, F S, Wegener, G & Joca, S R 2021, ' Co-administration of cannabidiol and ketamine induces antidepressant-like effects devoid of hyperlocomotor side-effects ', Neuropharmacology, vol. 195, 108679 . https://doi.org/10.1016/j.neuropharm.2021.108679
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Background and Purpose Although useful as a rapid-acting antidepressant drug, ketamine is known to induce psychotomimetic effects, which may interfere with its therapeutic use. Cannabidiol (CBD) is a non-psychostimulant compound from Cannabis sativa,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57caf2bdb3ff52ca458fee4769bf6168
https://pure.au.dk/ws/files/274012168/1_s2.0_S0028390821002343_main.pdf