The effect of disodium cromoglycate and ketotifen on the excretion of histamine and N tau-methylimidazole acetic acid in urine of patients with mastocytosis

Autor: Malcolm W. Greaves, E Wong, P. Norris, NB Rendell, AI Mallet

Treatment of four mastocytosis patients with the mast cell stabilising drugs, disodium cromoglycate and ketotifen failed to alter significantly the urinary excretion levels of histamine or N tau-methylimidazole acetic acid. No clinical improvement wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851daeaf79250cf2a74dc7ef144324fb
https://europepmc.org/articles/PMC1379709/

Contactin-1 links autoimmune neuropathy and membranous glomerulonephritis.

Autor: Fehmi J; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom., Davies AJ; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom., Antonelou M; University College London Department of Renal Medicine, Royal Free Hospital, London, United Kingdom., Keddie S; Centre for Neuromuscular Disease, National Hospital of Neurology and Neurosurgery and Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London, United Kingdom., Pikkupeura S; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom., Querol L; Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain., Delmont E; Referral Centre for ALS and Neuromuscular Diseases, Hospital La Timone, Marseille, France., Cortese A; Centre for Neuromuscular Disease, National Hospital of Neurology and Neurosurgery and Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London, United Kingdom.; Department of Brain and Behaviour sciences, University of Pavia, Pavia, Italy., Franciotta D; IRCCS, Mondino Foundation, Pavia, Italy., Persson S; Faculty of Medicine, Department of Clinical Sciences Lund, Neurology, Lund University, Lund, Sweden., Barratt J; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom., Pepper R; University College London Department of Renal Medicine, Royal Free Hospital, London, United Kingdom., Farinha F; Centre for Rheumatology and Bloomsbury Rheumatology Unit, Division of Medicine, University College London, London, United Kingdom., Rahman A; Centre for Rheumatology and Bloomsbury Rheumatology Unit, Division of Medicine, University College London, London, United Kingdom., Canetti D; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, United Kingdom., Gilbertson JA; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, United Kingdom., Rendell NB; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, United Kingdom., Radunovic A; Barts Neuromuscular Diseases Centre, Royal London Hospital, London, United Kingdom., Minton T; Institute of Clinical Neurosciences, University of Bristol, Bristol, United Kingdom., Fuller G; Department of Neurology, Gloucestershire Royal Hospital, Gloucester, United Kingdom., Murphy SM; Department of Neurology, Tallaght University Hospital & Academic Unit of Neurology, Trinity College, Dublin, Ireland., Carr AS; Centre for Neuromuscular Disease, National Hospital of Neurology and Neurosurgery and Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London, United Kingdom., Reilly MR; Centre for Neuromuscular Disease, National Hospital of Neurology and Neurosurgery and Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London, United Kingdom., Eftimov F; Department of Neurology and Neurophysiology, Amsterdam Neuroscience, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands., Wieske L; Department of Neurology and Neurophysiology, Amsterdam Neuroscience, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands., Teunissen CE; Department of Neurology and Neurophysiology, Amsterdam Neuroscience, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands., Roberts ISD; Department of Cellular Pathology, John Radcliffe Hospital, Oxford, United Kingdom., Ashman N; Barts Renal Unit, The Royal London Hospital, London, United Kingdom., Salama AD; University College London Department of Renal Medicine, Royal Free Hospital, London, United Kingdom., Rinaldi S; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.

Publikováno v: PloS one [PLoS One] 2023 Mar 09; Vol. 18 (3), pp. e0281156. Date of Electronic Publication: 2023 Mar 09 (Print Publication: 2023).

C. elegans feed yolk to their young in a form of primitive lactation.

Autor: Kern CC; Institute of Healthy Ageing, and Research Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK., Townsend S; Institute of Healthy Ageing, and Research Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK.; Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Salzmann A; Institute of Healthy Ageing, and Research Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK., Rendell NB; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, NW3 2PF, UK., Taylor GW; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, NW3 2PF, UK., Comisel RM; Institute of Healthy Ageing, and Research Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK., Foukas LC; Institute of Healthy Ageing, and Research Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK., Bähler J; Institute of Healthy Ageing, and Research Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK., Gems D; Institute of Healthy Ageing, and Research Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK. david.gems@ucl.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2021 Oct 05; Vol. 12 (1), pp. 5801. Date of Electronic Publication: 2021 Oct 05.

Lysozyme amyloid: evidence for the W64R variant by proteomics in the absence of the wild type protein.

Autor: Moura A; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK., Nocerino P; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK., Gilbertson JA; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK., Rendell NB; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK., Mangione PP; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK.; Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy., Verona G; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK., Rowczenio D; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK., Gillmore JD; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK., Taylor GW; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK., Bellotti V; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK.; Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy., Canetti D; Wolfson Drug Discovery Unit and National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, UK.

Publikováno v: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis [Amyloid] 2020 Sep; Vol. 27 (3), pp. 206-207. Date of Electronic Publication: 2020 Feb 18.

The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis.

Autor: Rezk T; National Amyloidosis Centre, University College London, London, UK.; Department of Renal Medicine, University College London, London, UK., Gilbertson JA; National Amyloidosis Centre, University College London, London, UK., Mangione PP; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, Royal Free Campus, University College London, London, UK.; Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy., Rowczenio D; National Amyloidosis Centre, University College London, London, UK., Rendell NB; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, Royal Free Campus, University College London, London, UK., Canetti D; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, Royal Free Campus, University College London, London, UK., Lachmann HJ; National Amyloidosis Centre, University College London, London, UK., Wechalekar AD; National Amyloidosis Centre, University College London, London, UK., Bass P; Department of Renal Medicine, University College London, London, UK., Hawkins PN; National Amyloidosis Centre, University College London, London, UK., Bellotti V; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, Royal Free Campus, University College London, London, UK.; Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy., Taylor GW; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, Royal Free Campus, University College London, London, UK., Gillmore JD; National Amyloidosis Centre, University College London, London, UK.

Publikováno v: The journal of pathology. Clinical research [J Pathol Clin Res] 2019 Jul; Vol. 5 (3), pp. 145-153. Date of Electronic Publication: 2019 Apr 02.